Results 1 to 10 of about 94,345 (348)
Identification of erythroferrone as an erythroid regulator of iron metabolism. [PDF]
, 2014 Recovery from blood loss requires a greatly enhanced supply of iron to support expanded erythropoiesis. After hemorrhage, suppression of the iron-regulatory hormone hepcidin allows increased iron absorption and mobilization from stores.
Ganz, Tomas +5 more
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Erythropoiesis: insights into pathophysiology and treatments in 2017
Molecular Medicine, 2018 Erythropoiesis is a tightly-regulated and complex process originating in the bone marrow from a multipotent stem cell and terminating in a mature, enucleated erythrocyte.
Andrea Zivot +3 more
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Haematologica, 2023 Enhancer of zeste homolog 2 (EZH2) is the lysine methyltransferase of polycomb repressive complex 2 (PRC2) that catalyzes H3K27 tri-methylation. Aberrant expression and loss-of-function mutations of EZH2 have been demonstrated to be tightly associated ...
Mengjia Li +13 more
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MIF contributes to Trypanosoma brucei associated immunopathogenicity development [PDF]
, 2014 African trypanosomiasis is a chronic debilitating disease affecting the health and economic well-being of many people in developing countries. The pathogenicity associated with this disease involves a persistent inflammatory response, whereby M1-type ...
Beschin, Alain +11 more
core +4 more sources
Frontiers in Physiology, 2018 RASA3 is a Ras GTPase activating protein that plays a critical role in blood formation. The autosomal recessive mouse model scat (severe combined anemia and thrombocytopenia) carries a missense mutation in Rasa3.
Emily S. Hartman +8 more
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Blood, 2017 In this issue of Blood, Alvarez-Dominguez et al reveal the strategies used to achieve precise but highly dynamic translational control of protein synthesis during red blood cell development.
openaire +3 more sources
Research advances in erythrocyte regeneration sources and methods in vitro
Cell Regeneration, 2018 Erythrocytes (red blood cells, RBCs) facilitate gas exchange in the lungs and transport oxygen to the tissues. The human body must maintain erythrocyte regeneration to support metabolically active cells and tissues.
Shuming Sun, Yuanliang Peng, Jing Liu
doaj +1 more source
Regulation of erythropoiesis: emerging concepts and therapeutic implications
Hematology, 2023 The process of erythropoiesis is complex and involves the transfer of cells from the yolk sac to the fetal hepar and, ultimately, to the bone marrow during embryonic development.
Pu Tang, Huaquan Wang
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Effects of the Zanzibar School-Based Deworming Program on Iron Status of Children. [PDF]
, 1998 We evaluated the effects of the Zanzibar school-based deworming program on the iron status of primary school children. Parasitologic and nutritional assessments were carried out at baseline, 6 mo, and 12 mo in 4 nonprogram schools (n = 1002), 4 schools ...
Albonico, M +5 more
core +1 more source
Blood, 2009 AbstractMultisubunit complexes containing molecular chaperones regulate protein production, stability, and degradation in virtually every cell type. We are beginning to recognize how generalized and tissue-specific chaperones regulate specialized aspects of erythropoiesis.
Mitchell J, Weiss, Camila O, dos Santos
openaire +3 more sources