Results 21 to 30 of about 79,234 (272)

Adrenergic Modulation of Erythropoiesis After Trauma

Frontiers in Physiology, 2022
Severe traumatic injury results in a cascade of systemic changes which negatively affect normal erythropoiesis. Immediately after injury, acute blood loss leads to anemia, however, patients can remain anemic for as long as 6 months after injury. Research
Jennifer A. Munley, Lauren S. Kelly, Alicia M. Mohr   +2 more
doaj   +1 more source

Oxidation and erythropoiesis

Current Opinion in Hematology, 2019
Purpose of review Erythropoiesis is a complex multistep process going from committed erythroid progenitors to mature red cells. Although recent advances allow the characterization of some components of erythropoiesis, much still remains to be investigated particularly on stress erythropoiesis.
Matte A., De Franceschi L.
openaire   +3 more sources

Hepcidin as a predictive factor and therapeutic target in erythropoiesis-stimulating agent treatment for anemia of chronic disease in rats

Haematologica, 2014
Anemia of chronic disease is a multifactorial disorder, resulting mainly from inflammation-driven reticuloendothelial iron retention, impaired erythropoiesis, and reduced biological activity of erythropoietin.
Milan Theurl, Manfred Nairz, Andrea Schroll, Thomas Sonnweber, Malte Asshoff, David Haschka, Markus Seifert, Wolfgang Willenbacher, Doris Wilflingseder, Wilfried Posch, Anthony T. Murphy, Derrick R. Witcher, Igor Theurl, Günter Weiss   +13 more
doaj   +1 more source

Mechanisms controlling anaemia in Trypanosoma congolense infected mice. [PDF]

, 2009
Trypanosoma congolense are extracellular protozoan parasites of the blood stream of artiodactyls and are one of the main constraints on cattle production in Africa.
A Kobayashi, A Shamseddine, AI Su, AJ Nok, Andy Brass, B Mertens, B Stijlemans, B Stijlemans, B Vanhollebeke, Birgit Rathkolb, BM Bolstad, C Beaumont, C Li, CA Facer, CA Schaer, Delnaz Roshandel, DM Wrighting, E Nemeth, E Nemeth, E Nemeth, Eckard Wolf, Fuad Iraqi, G Weiss, Gd Haan, Gordon Langsley, Harry A. Noyes, HC Greenblatt, Helen Hulme, Helmut Fuchs, HH Kazazian, J Naessens, J Naessens, J Naessens, J Naessens, Jan Naessens, JCM Trail, KAN Esievo, KC Corbit, LY Shih, M Murray, M Murray, M Shi, M Shi, M Sileghem, M Sileghem, Martin Hrabé de Angelis, Mohammad H. Alimohammadian, Morris Agaba, MR Rifkin, N Mabbott, O Van Assendaelft, PM Kristjanson, R Ferreira, RC Gregory, RH Wang, RKG Assoku, RM Ngure, S Kemp, S Kierstein, S Magez, S Magez, S Taniguchi, SH Goh, SJ Kemp, SK Moestrup, Stephen Kemp, T Sato, TC Cheng, Valerie Gailus-Durner, VO Anosa, W Morrison, W Morrison, W Zumkeller, Y Liang, Y Nakamura   +74 more
core   +3 more sources

Decoding erythropoiesis [PDF]

Blood, 2017
In this issue of Blood, Alvarez-Dominguez et al reveal the strategies used to achieve precise but highly dynamic translational control of protein synthesis during red blood cell development.
openaire   +3 more sources

Molecular mechanisms of regulation of erythropoiesis and stress erythropoiesis [PDF]

Medicinski Podmladak
Erythropoiesis under basal conditions involves the continuous production of new erythrocytes at a constant rate. During the adult period, erythropoiesis takes place primarily in the bone marrow and has a substantial capacity.
Momčilović Sanja, Bogdanović Andrija, Vignjević-Petrinović Sanja   +2 more
doaj   +1 more source

LYVE1 Marks the Divergence of Yolk Sac Definitive Hemogenic Endothelium from the Primitive Erythroid Lineage. [PDF]

, 2016
The contribution of the different waves and sites of developmental hematopoiesis to fetal and adult blood production remains unclear. Here, we identify lymphatic vessel endothelial hyaluronan receptor-1 (LYVE1) as a marker of yolk sac (YS ...
Ghorbanian, Yasamine, Inlay, Matthew A, Kim, Yeon Joo, Lee, Lydia K, Mikkola, Hanna KA, Wang, Wenyuan, Wang, Yanling, Weissman, Irving L   +7 more
core   +1 more source

A Model of the Cellular Iron Homeostasis Network Using Semi-Formal Methods for Parameter Space Exploration [PDF]

EPTCS 92, 2012, pp. 42-57, 2012
This paper presents a novel framework for the modeling of biological networks. It makes use of recent tools analyzing the robust satisfaction of properties of (hybrid) dynamical systems. The main challenge of this approach as applied to biological systems is to get access to the relevant parameter sets despite gaps in the available knowledge.
arxiv   +1 more source

Control of globin gene expression by Kruppel-like factors [PDF]

, 2014
Kruppel-like factors (KLFs) are a family of seventeen proteins designated KLF1 to KLF17. KLFs are transcriptional factors that bind GC-rich sequences such as CACCC elements. The DNA binds to KLFs via three carboxyl-terminal Cys-2/His-2 zinc fingers. KLFs
Borg, Joseph, Grech, Laura
core   +1 more source

Nonparametric inference procedure for percentiles of the random effects distribution in meta-analysis [PDF]

Annals of Applied Statistics 2010, Vol. 4, No. 1, 520-532, 2010
To investigate whether treating cancer patients with erythropoiesis-stimulating agents (ESAs) would increase the mortality risk, Bennett et al. [Journal of the American Medical Association 299 (2008) 914--924] conducted a meta-analysis with the data from 52 phase III trials comparing ESAs with placebo or standard of care.
arxiv   +1 more source