Results 41 to 50 of about 79,234 (272)
FOXO1 regulates pentose phosphate pathway-mediated induction of developmental erythropoiesis
Frontiers in Cell and Developmental Biology, 2022 Primitive, neonatal and adult erythroid cells have been previously shown to have an active pentose phosphate pathway (PPP) that fuels various processes.
Anuntxi Monsalve +2 more
doaj +1 more source
A polymorphism at IGF1 locus is associated with anemia [PDF]
, 2017 In vitro and in vivo studies suggest that IGF-1 has a role in erythropoiesis. There is evidence that the rs35767 C/T polymorphism near IGF1 is associated with plasma IGF-1 levels.
Andreozzi F +5 more
core +1 more source
Transferrin Receptors in Erythropoiesis [PDF]
International Journal of Molecular Sciences, 2020 Erythropoiesis is a highly dynamic process giving rise to red blood cells from hematopoietic stem cells present in the bone marrow. Red blood cells transport oxygen to tissues thanks to the hemoglobin comprised of α- and β-globin chains and of iron-containing hemes.
Cyrielle Richard, Frédérique Verdier
openaire +3 more sources
Modelling hematopoiesis mediated by growth factors with applications to periodic hematological diseases [PDF]
, 2006 Hematopoiesis is a complex biological process that leads to the production and regulation of blood cells. It is based upon differentiation of stem cells under the action of growth factors.
Adimy, Mostafa +2 more
core +5 more sources
Blood, 1971 Abstract Rabbits were rendered anemic by phlebotomy, by parenteral administration of phenylhydrazine and by phlebotomy coupled with transfusion of nonviable erythrocytes. Measurements were made of the number and iron uptake of immature erythroid cells, and the size and hemoglobin content of the circulating erythrocytes.
Peter Jacobs, Clement A. Finch
openaire +3 more sources
Hepcidin secretion was not directly proportional to intracellular iron-loading in recombinant-TfR1 HepG2 cells: short communication [PDF]
, 2020 Hepcidin is the master regulator of systemic iron homeostasis and its dysregulation is observed in several chronic liver diseases. Unlike the extracellular iron-sensing mechanisms, the intracellular iron-sensing mechanisms in the hepatocytes that lead to
Busbridge Mark +7 more
core +2 more sources
International Journal of Integrated Health Sciences, 2021 Objective: To determine the mechanism of erythropoiesis that led to anemia using the Immature Reticulocyte Fraction (IRF) parameter in various clinical phases of dengue fever.
Amaylia Oehadian +5 more
doaj +1 more source
TAM receptors and the regulation of erythropoiesis in mice
Haematologica, 2009 Background TAM receptors (Tyro3, Axl and Mer) are expressed in hematopoietic tissues. The roles of the three receptors in hematopoiesis are, however, largely unknown.
Hongmei Tang +5 more
doaj +1 more source
Advanced Therapeutics, EarlyView.Hispidulin disrupts the KITENIN/ErbB4 oncogenic complex and inhibits KITENIN‐mediated AP‐1 activity, cell invasion, and aerobic glycolysis. It also suppresses the production of cancer‐associated metabolites and downregulates transcriptional regulators downstream of the KITENIN complex.
Mücahit Varlı +7 more
wiley +1 more source
Clinical Case Reports, 2022 Extramedullary hematopoiesis in the posterior mediastinum is rare. Our case interested a 28‐year‐old man with a history of eosinophilia with FIP1L1‐PDGFRA fusion gene who had a mediastinal mass surgically excised. Pathological examination concluded to an
Sassi Farah +6 more
doaj +1 more source