Results 51 to 60 of about 79,234 (272)

Effects of the Zanzibar School-Based Deworming Program on Iron Status of Children. [PDF]

, 1998
We evaluated the effects of the Zanzibar school-based deworming program on the iron status of primary school children. Parasitologic and nutritional assessments were carried out at baseline, 6 mo, and 12 mo in 4 nonprogram schools (n = 1002), 4 schools ...
Albonico, M, Chwaya, H M, Savioli, L, Schulze, K J, Stoltzfus, R J, Tielsch, J M   +5 more
core   +1 more source

Phylogeny and Ontogeny of Erythropoiesis [PDF]

BioMed Research International, 2015
Erythrocytes are essential for survival of vertebrates due to their ability to take up, bind, and transport oxygen. Recent study clarified that the number of cells in adult human is ~3.7 × 1013 cells and about 2/3 are erythrocytes (Bianconi et al. (2013) Ann Hum Biol. 40: 463).
Małgorzata Witeska, Wataru Nunomura, Takashi Kato, Ritsuko Shimizu, Aurora M. Cianciarullo, Aurora M. Cianciarullo   +5 more
openaire   +3 more sources

KLF1 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through Regulation of Wnt/β‐Catenin Signaling Pathway

Advanced Science, EarlyView.
In KLF1‐on (neonatal and Klf1 overexpression hearts) models, KLF1 regulates Wnt/β‐catenin signaling pathway and the expression of cell proliferation‐related genes via transcriptional and epigenetic mechanisms, which induces cardiomyocyte proliferation and cardiac regeneration in mice after myocardial infarction.
Yanglin Hao, Xi Zhang, Shuan Ran, Yuan Li, Weicong Ye, Song Wang, Xiaohan Li, Zilong Luo, Jiulu Zhao, Junjie Zong, Kexiao Zheng, Ran Li, Han Zhang, Longyong Lai, Pinyan Huang, Zifeng Zou, Wang Zhan, Zhang Yue, Jie Wu, Jiahong Xia   +19 more
wiley   +1 more source

Is There any Relationship Between the Repeated Complications of Sickle Cell Disease and the Potential Development of Acute Leukemia?

Oncology and Therapy
Sickle cell disease (SCD) is a severe monogenic hereditary hemoglobinopathy that is characterized by repeated clinical and biological manifestations able to generate stress erythopoiesis.
Giovanna Cannas, Mohamed Elhamri, Xavier Thomas   +2 more
doaj   +1 more source

Iron Loading and Overloading due to Ineffective Erythropoiesis

Advances in Hematology, 2010
Erythropoiesis describes the hematopoietic process of cell proliferation and differentiation that results in the production of mature circulating erythrocytes.
Toshihiko Tanno, Jeffery L. Miller
doaj   +1 more source

Rac1 and Rac2 GTPases are necessary for early erythropoietic expansion in the bone marrow but not in the spleen

Haematologica, 2010
Background The small Rho GTPases Rac1 and Rac2 have both overlapping and distinct roles in actin organization, cell survival, and proliferation in various hematopoietic cell lineages. The role of these Rac GTPases in erythropoiesis has not yet been fully
Theodosia A. Kalfa, Suvarnamala Pushkaran, Xiaoling Zhang, James F. Johnson, Dao Pan, Deidre Daria, Hartmut Geiger, Jose A. Cancelas, David A. Williams, Yi Zheng   +9 more
doaj   +1 more source

Only complete rejoining of DNA strand breaks after UVC allows K562 cell proliferation and DMSO induction of erythropoiesis [PDF]

, 2008
DNA strand breaks are early intermediates of the repair of UVC-induced DNA damage, however, since they severely impair cellular activities, their presence should be limited in time.
AVALLONE, BICE, FORESTI, MAGDA
core   +1 more source

Inhibition of Ferroptosis Delays Aging and Extends Healthspan Across Multiple Species

Advanced Science, EarlyView.
This study identifies ferroptosis as a key driver of cellular senescence, with its inhibition delaying aging and extending healthspan across species. During senescence, ferroptosis worsens, increasing oxidative stress and lipid peroxidation, which accelerate aging.
Hai‐Jun Fu, Xing‐Yue Zhou, Da‐Lian Qin, Qan Qiao, Qiao‐Zhi Wang, Shi‐Ying Li, Yun‐Fei Zhu, Ya‐Ping Li, Jiang‐Min Zhou, Hui Cai, Fei‐Hong Huang, Lu Yu, Long Wang, An‐Guo Wu, Jian‐Ming Wu, Xiao‐Gang Zhou   +15 more
wiley   +1 more source

Effect of Neopterin on Splenic Erythropoiesis in Mice

Pteridines, 2010
Neopterin is produced by monocytes and is a biomarker for inflammation. We recently found that neopterin induces stromal cells to produce cytokines that suppress erythropoiesis in the bone marrow of mice.
Tsuboi Isao, Harada Tomonori, Oshima Hideki, Aizawa Shin   +3 more
doaj   +1 more source

Assembly of Protein 4.1 during Chicken Erythroid Differentiation [PDF]

, 1986
Protein 4.1 is a peripheral membrane protein that strengthens the actin-spectrin based membrane skeleton of the red blood cell and also serves to attach this structure to the plasma membrane. In avian erythrocytes it exists as a family of closely related
Lazarides, Elias, Staufenbiel, Matthias
core   +1 more source