Results 71 to 80 of about 91,872 (258)
eLife, 2015 NCOA4 is a selective cargo receptor for the autophagic turnover of ferritin, a process critical for regulation of intracellular iron bioavailability. However, how ferritinophagy flux is controlled and the roles of NCOA4 in iron-dependent processes are ...
Joseph D Mancias +9 more
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Intravascular Large B-Cell Lymphoma Presenting as Dementia and Hemolytic Anemia [PDF]
, 2010 Background: Intravascular lymphoma (IVL) is an uncommon disease characterized by atypical lymphoid cells growing inside the lumina of small vessels. The diversity of clinical presentation due to possible involvement of multiple organs often complicates ...
Ahle, Guido +6 more
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Erythropoiesis in Fanconi's anemia [PDF]
Blood, 1991 Abstract Fanconi's anemia (FA) is an autosomal recessive condition in which greater than 90% of the homozygotes develop aplastic anemia. To determine the relation between erythroid progenitors and clinical status, blood and marrow mononuclear cells were cultured in methyl cellulose with erythropoietin, plus other hematopoietic growth ...
Blanche P. Alter +2 more
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Frontiers in Cell and Developmental Biology, 2020 Erythropoiesis is the most robust cellular differentiation and proliferation system, with a production of ∼2 × 1011 cells per day. In this fine-tuned process, the hematopoietic stem cells (HSCs) generate erythroid progenitors, which proliferate and ...
Alvaro M. Gonzalez-Ibanez +11 more
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Studies on erythropoiesis II. In vitro studies on red cell proliferation under varied oxygen tension [PDF]
, 1964 For the purpose to reveal the mechanism of the stimulated erythropoiesis in anemic condition, the author observed the numerical changes of the erythroblasts from normal rabbit bone marrow cultured under the environment of varied oxygen tensions, and ...
Shibata, Takashi
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Erythropoiesis: Development and Differentiation [PDF]
Cold Spring Harbor Perspectives in Medicine, 2013 Through their oxygen delivery function, red blood cells are pivotal to the healthy existence of all vertebrate organisms. These cells are required during all stages of life--embryonic, fetal, neonatal, adolescent, and adult. In the adult, red blood cells are the terminally differentiated end-product cells of a complex hierarchy of hematopoietic ...
Elaine Dzierzak, Sjaak Philipsen
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Blood, 2009 AbstractMultisubunit complexes containing molecular chaperones regulate protein production, stability, and degradation in virtually every cell type. We are beginning to recognize how generalized and tissue-specific chaperones regulate specialized aspects of erythropoiesis.
Mitchell J, Weiss, Camila O, dos Santos
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Advances in the generation of erythrocytes from stem cells in vitro
HematologyRed blood cell transfusion is the main treatment to improve anemia caused by many reasons and has important clinical application value. However, the supply of red blood cells at home and abroad is currently very tight.
Yating Ling +4 more
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The Keio Journal of Medicine, 1977 Various culture systems are now available to study erythropoiesis in vitro. These include suspension and cloning culture techniques. Suspension culture techniques are frequently used for studying biochemical changes in erythroid cells, while cloning culture techniques are suited for investigating the nature of erythroid stem cells.
Junzo Kaneko, Junzo Kaneko
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Hematology, Transfusion and Cell TherapyBackground: Anemia-associated chronic kidney disease increases in more advanced stages with a subsequent acceleration in renal impairment progressing to end-stage renal disease. Although hepcidin and erythroferrone have been described as novel biomarkers
Salwa Bakr +6 more
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