Results 81 to 90 of about 91,872 (258)

TREX1 D18N mice fail to process erythroblast DNA resulting in inflammation and dysfunctional erythropoiesis

Autoimmunity, 2018
Anaemia is commonly observed in chronic inflammatory conditions, including systemic lupus erythematosus (SLE), where ∼50% of patients display clinical signs of anaemia.
Stephen L. Rego, Scott Harvey, Sean R. Simpson, Wayne O. Hemphill, Zachariah A. McIver, Jason M. Grayson, Fred W. Perrino   +6 more
doaj   +1 more source

Transient but not genetic loss of miR-451 attenuates the development of pulmonary arterial hypertension [PDF]

, 2013
<b>Rationale:</b> MicroRNAs are small non-coding RNAs involved in the regulation of gene expression and have recently been implicated in the development of pulmonary arterial hypertension (PAH).
Baker, Andrew H., Dempsie, Yvonne, Grant, Jennifer S., MacLean, Margaret R., Morecroft, Ian, van Rooij, Eva   +5 more
core   +2 more sources

Nonparametric inference procedure for percentiles of the random effects distribution in meta-analysis

, 2010
To investigate whether treating cancer patients with erythropoiesis-stimulating agents (ESAs) would increase the mortality risk, Bennett et al. [Journal of the American Medical Association 299 (2008) 914--924] conducted a meta-analysis with the data from
Cai, Tianxi, Tian, Lu, Wang, Rui, Wei, L. J.   +3 more
core   +1 more source

The Italian Regulatory Guidelines for the implementation of Patient Blood Management [PDF]

, 2017
Comment in Towards the implementation of patient blood management across Europe.
Antonioli, Paola, Biancofiore, Gianni, Gentili, Sara, Liumbruno, Giancarlo M., Marano, Giuseppe, Pupella, Simonetta, Rafanelli, Daniela, Vaglio, Stefania, Velati, Claudio   +8 more
core   +1 more source

"Splenism" - the function of spleen, as the organ conducting the interrelation of the circulatory system and hematopoiesis

Patologìâ, 2013
On Wistar rats splenic involvement into the regulation of erythropoiesis was studied. Splenomegaly was reproduced for this both by ligation of splenic veins and transfusion of suspension of washed erythrocytes that leaded to the pronounced increase in ...
V.I. Filimonov, N.V. Stepanova, I.E. Sukhomlinova, M.A. Tikhonovskaya, G.I. Bessarab, D.A. Putilin, G.V. Pirtya   +6 more
doaj   +1 more source

Suppression of erythropoiesis by actinomycin D. 3. The effect of actinomycin D on the hemoglobin level of bone marrow erythrocytes and erythroblasts [PDF]

, 1969
For the purpose of revealing whether or not hemoglobin synthesis is inhibited by the AMD, the author estimated the hemoglobin level of AMD treated anilmals by microspectrophotometer, and found that the hemoglobin levels of all the developmental stages of
Okada, Shigeru
core   +1 more source

Delineation of erythropoietic intermediates by flow cytometry

Frontiers in Hematology
Erythropoiesis occurs through specification from multipotent progenitors to erythroid restricted potential, expansion of erythroid progenitors, and terminal maturation of precursors to red blood cells.
Kathleen E. McGrath
doaj   +1 more source

A Shift in Myeloid Cell Phenotype via Down Regulation of Siglec-1 in Island Macrophages of Bone Marrow Is Associated With Decreased Late Erythroblasts Seen in Anemia of Critical Illness

Frontiers in Medicine, 2019
Burn injury has been shown to significantly dampen erythropoiesis in both burn patients and in murine models. Our previous findings elucidated the erythropoietin independent defects in red cell development stages involving erythroid progenitor production
Shirin Hasan, Shirin Hasan, Maria Camargo Johnson, Maria Camargo Johnson, Ameet R. Kini, Anthony J. Baldea, Kuzhali Muthumalaiappan, Kuzhali Muthumalaiappan   +7 more
doaj   +1 more source

Bench-to-bedside review: Erythropoietin and its derivatives as therapies in critical care [PDF]

, 2012
Author can archive publisher's pdf. Free via Creative Commons: CC-BENCHTOBEDSIDE-2.0.
Nandra, KK, Patel, NSA, Thiemermann, C
core   +1 more source

NFAT-mediated defects in erythropoiesis cause anemia in Il2-/- mice. [PDF]

, 2018
The role of NFAT family transcription factors in erythropoiesis is so far unknown, although their involvement has been suggested previously. We have shown recently that Il2-/- mice develop severe anemia due to defects in KLF1 activity during BM ...
Alt, Berberich-Siebelt, Bieker, Bierer, Bommhardt, Castro, Chuvpilo, Costantini, Crispino, Crompton, Fried, Glimcher, Grosveld, Horak, Ingber, Karur, Khachigian, Kim, Koretzky, Krammer, Leonard, Lodish, Lodish, Lodish, Lodish, Lodish, Lopez-Botet, Lux, Macian, Mak, Mak, Olson, Olson, Orkin, Orkin, Orkin, Orkin, Orkin, Palis, Patra, Patra, Patra, Rao, Roifman, Rudensky, Schmitt, Serfling, Shivdasani, Soreq, Sprent, Stoeckert, Toker   +51 more
core   +2 more sources