Results 31 to 40 of about 144,316 (318)
Kidney International, 1999 Serum ferritin concentration is most informative in estimating the amount of storage iron available for a particular individual. The serum transferrin receptor concentration, in contrast to serum ferritin, provides direct information about any deficit in the adequacy of iron supply to the erythropoiesis.
Kaltwasser, Joachim P. +1 more
openaire +2 more sources
Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway [PDF]
, 2003 Objective. Erythropoietin (EPO) is a key regulator of erythropoiesis, playing a role in both the proliferation and differentiation of erythroid cells.
Bieber +36 more
core +1 more source
Serum erythropoietin levels, breast cancer and breast cancer-initiating cells
Breast Cancer Research, 2019 Background Cancer is frequently associated with tumor-related anemia, and many chemotherapeutic agents impair hematopoiesis, leading to impaired quality of life for affected patients.
Kruttika Bhat +11 more
doaj +1 more source
Effect of erythropoietin administration on proteins participating in iron homeostasis in Tmprss6-mutated mask mice. [PDF]
PLoS ONE, 2017 Tmprss6-mutated mask mice display iron deficiency anemia and high expression of hepcidin. The aim of the study was to determine the effect of erythropoietin administration on proteins participating in the control of iron homeostasis in the liver and ...
Jana Frýdlová +5 more
doaj +1 more source
PLoS ONE, 2015 BackgroundAlthough erythropoietin has been used for decades in the treatment of anemia, data regarding endogenous levels in the general population are scarce.
Niels Grote Beverborg +9 more
doaj +1 more source
Identification of erythroferrone as an erythroid regulator of iron metabolism. [PDF]
, 2014 Recovery from blood loss requires a greatly enhanced supply of iron to support expanded erythropoiesis. After hemorrhage, suppression of the iron-regulatory hormone hepcidin allows increased iron absorption and mobilization from stores.
Ganz, Tomas +5 more
core +1 more source
Definition of a family of tissue-protective cytokines using functional cluster analysis: a proof-of-concept study [PDF]
, 2014 The discovery of the tissue-protective activities of erythropoietin (EPO) has underlined the importance of some cytokines in tissue-protection, repair, and remodeling.
Annenkov, Alexander +4 more
core +3 more sources
Purification of Erythropoietin [PDF]
Proceedings of the National Academy of Sciences, 1971 Erythropoietin, the hormone that is the primary regulator of erythrocyte production, has been purified from anemic-sheep plasma, with a purification factor of more than 1 million. Gel electrophoresis shows that the major contaminant is desialated erythropoietin.
E, Goldwasser, C K, Kung
openaire +2 more sources
Use of Recombinant Human Erythropoietin in Renal Anemia in Children
Bangabandhu Sheikh Mujib Medical University Journal, 2009 Erythropoietin is a hormone highly effective as like as natural erythropoietin to maintain target hemoglobin and hematocrit level in renal anemia. Its advantage over blood transfusion has been proved by improving the quality of life and decreasing ...
Habibur Rahman +4 more
doaj +1 more source
Disease Models & Mechanisms, 2013 SUMMARY There is limited evidence that the tissue-protective effects of erythropoietin are mediated by a heterocomplex of the erythropoietin receptor and the β-common receptor (‘tissue-protective receptor’), which is pharmacologically distinct from the ...
Areeg I. Khan +8 more
doaj +1 more source