STAT1 activation in association with JAK2 exon 12 mutations [PDF]
La inclusión de la perspectiva de género en la actividad jurisdiccional es una demanda sostenida de los colectivos feministas y de mujeres, dado que las sentencias tienen un poder performativo y envían un mensaje a la sociedad: “[…] tienen un poder ...
Godfrey, A.L. +33 more
core +4 more sources
The Prevalence and Implications of Polypharmacy in Individuals With Type 1 Diabetes
Polypharmacy is increasingly recognized as a relevant issue in diabetes care, but its prevalence and clinical relevance in individuals with type 1 diabetes remain underexplored. This study aimed to determine the prevalence of polypharmacy and to identify associated clinical and psychological factors. Participants were recruited from a tertiary diabetes
Namam Ali +4 more
wiley +1 more source
Erythrocytes and Erythropoietin [PDF]
This special issue focuses on erythrocytes and erythropoietin including original research and review articles on the cellular physiology of erythrocytes and of erythrocyte-associated disorders. Moreover, the special issue includes papers on the action of erythropoietin and hypoxia-inducible factors on a cellular level.
Michael Föller +3 more
openaire +3 more sources
CERA Detection and Stability in Blood Versus Urine
This study presents comparative data on CERA detection in serum and urine samples, highlighting adverse analytical findings (AAFs) in serum that were undetected in corresponding urine samples. This shift would significantly improve the efficiency and sensitivity of CERA detection in doping control, ensuring more effective doping control programs ...
Olivier Salamin +4 more
wiley +1 more source
Erythropoietin blockade inhibits the induction of tumor angiogenesis and progression. [PDF]
The induction of tumor angiogenesis, a pathologic process critical for tumor progression, is mediated by multiple regulatory factors released by tumor and host cells.
Matthew E Hardee +8 more
doaj +1 more source
Toxicity Analysis in the ADEBAR Trial: Sequential Anthracycline-Taxane Therapy Compared with FEC120 for the Adjuvant Treatment of High-Risk Breast Cancer [PDF]
Background: Data from meta-analyses have shown taxane-containing therapies to be superior to anthracycline-based treatments for high-risk breast cancer. Patients and Methods: The ADEBAR trial was a multicenter phase Ill trial in which patients with lymph
Aivazova-Fuchs, Viktoria +16 more
core +1 more source
Improvement of EPO Transgene Detection From Polymeric Dried Blood Spots for Antidoping Application
This article presents an optimized protocol for gene doping detection. Starting from one spot DBS (20 μL), concentrated DNA was obtained and real‐time PCR parameters were adjusted for increased detection. Robust detection of 5000 copies/mL of transgene was validated for polymeric device TASSO M‐20.
Alexandre Marchand +2 more
wiley +1 more source
Influence of hemoglobin level and dose of administered recombinant human beta erythropoietin on survival of hemodialysis patients [PDF]
Background/Aim. In patients with end-stage renal disease, treatment with erythropoietin lowers cardiovascular morbidity, improves quality of life and patient survival.
Knežević Violeta +5 more
doaj +1 more source
Role of selenium in the pathophysiology of cardiorenal anaemia syndrome
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai +2 more
wiley +1 more source
Analysis of the publications devoted to the structure, functions, mechanism of action of erythropoietin is given in the article. Erythropoietin preparations derived from recombinant DNA technology are a mixture of isoforms with different biological ...
A. K. Yakovlev +9 more
doaj +1 more source

