Results 51 to 60 of about 136,514 (310)
Identification of erythroferrone as an erythroid regulator of iron metabolism. [PDF]
, 2014 Recovery from blood loss requires a greatly enhanced supply of iron to support expanded erythropoiesis. After hemorrhage, suppression of the iron-regulatory hormone hepcidin allows increased iron absorption and mobilization from stores.
Ganz, Tomas +5 more
core +1 more source
Biotechnology Progress, EarlyView.Abstract The production of disulfide‐containing recombinant proteins often requires refolding of inclusion bodies before purification. A pre‐refolding purification step is crucial for effective refolding because impurities in the inclusion bodies interfere with refolding and subsequent purification.
Shuichiro Kimura +4 more
wiley +1 more source
Acta Pharmaceutica, 2018 Oral delivery of protein drugs is greatly limited by low hydrophobicity, an important determinant for intestinal epithelial permeation and bioavailability.
Miklavžin Ana +3 more
doaj +1 more source
EFFECT OF ERYTHROPOIETIN ON CYTOKINE PRODUCTION BY STEM CELLS
Медицинская иммунология, 2019 Erythropoietin (EPO) is mainly used to stimulate erythropoiesis. Its cytoprotective effects upon other cells of the human body and animals were recently shown, in particular, anti-apoptotic effect was observed.
A. P. Lykov +6 more
doaj +1 more source
Erythropoietin blockade inhibits the induction of tumor angiogenesis and progression. [PDF]
PLoS ONE, 2007 The induction of tumor angiogenesis, a pathologic process critical for tumor progression, is mediated by multiple regulatory factors released by tumor and host cells.
Matthew E Hardee +8 more
doaj +1 more source
Contemporary Perspectives on Chronic Renal Disorders
Chronic Diseases and Translational Medicine, EarlyView.ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok +5 more
wiley +1 more source
Haematologica, 2018 The effects of erythropoietin on osteoblasts and bone formation are controversial. Since patients with myelodysplastic syndromes often display excessively high erythropoietin levels, we aimed to analyze the effect of erythropoietin on osteoblast function
Ekaterina Balaian +9 more
doaj +1 more source
Drug Testing and Analysis, EarlyView.Trends in adverse analytical findings (AAFs) for erythropoietin Receptor Agonist (ERAs) we examined to assess the impact of ERA testing and detection on athlete behavior. It was observed that the largest fraction of ERA AAFs occurs on the first sample ever taken from an athlete (43.2%), and that the ERA AAFs rates decline steadily as athletes continue ...
Tristan Equey +3 more
wiley +1 more source
Drug Testing and Analysis, EarlyView.Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario Thevis +2 more
wiley +1 more source
AMB Express, 2020 In this study, we evaluated the combined therapeutic efficacy of erythropoietin (a hematopoietic hormone produced by the fetal liver and kidney in response to inflammation and apoptosis) and sesame oil (from Sesamum indicum L.) on ischemic kidney injury ...
Liyu Ye +8 more
doaj +1 more source