Results 51 to 60 of about 187,553 (368)

Adding epoetin alfa to intense dose-dense adjuvant chemotherapy for breast cancer : randomized clinical trial [PDF]

open access: yes, 2013
BACKGROUND: The AGO-ETC trial compared 5-year relapse-free survival of intense dose-dense (IDD) sequential chemotherapy with epirubicin (E), paclitaxel (T), and cyclophosphamide (C) (IDD-ETC) every 2 weeks vs conventional scheduled epirubicin ...
Bois, Andreas du   +13 more
core   +1 more source

Erythropoietin attenuates cardiac dysfunction in experimental sepsis in mice via activation of the β-common receptor

open access: yesDisease Models & Mechanisms, 2013
SUMMARY There is limited evidence that the tissue-protective effects of erythropoietin are mediated by a heterocomplex of the erythropoietin receptor and the β-common receptor (‘tissue-protective receptor’), which is pharmacologically distinct from the ...
Areeg I. Khan   +8 more
doaj   +1 more source

A radioimmunoassay for erythropoietin [PDF]

open access: yesBlood, 1979
Abstract We describe the development of a radioimmunoassay (RIA) for erythropoietin. Antisera were raised in rabbits with an impure human urinary erythropoietin preparation used as immunogen, but with pure human erytropoietin serving as the labeled antigen in the RIA and as a primary standard.
Eugene Goldwasser, Judith B. Sherwood
openaire   +4 more sources

Inhibition of gentamicin–induced renal tubular cell necrosis [PDF]

open access: yesJournal of Nephropathology, 2012
Gentamicin nephrotoxicity limit its usage against gram negative bacteria. Most researches showed that antioxidant agents improved gentamicin nephrotoxicity.
Majid Tavafi
doaj   +1 more source

GDF15 Ameliorates Deoxynivalenol‐Induced Anemia by Resolving Ribosomal Stress–Mediated Erythropoietic Arrest

open access: yesAdvanced Science, EarlyView.
Deoxynivalenol induces anemia by disrupting hematopoietic homeostasis and impairing erythroid lineage commitment and differentiation via ribosomal stress–mediated G1/S cell cycle arrest. GDF15 supplementation alleviates this arrest through the β‐catenin–Myc–p21 signaling axis, highlighting GDF15 as a potential therapeutic target for DON‐induced ...
Yan Li   +12 more
wiley   +1 more source

Neopterin-induced Suppression of Erythropoietin Production In Vitro

open access: yesPteridines, 1995
The production of neopterin increases in several diseases with activation of the ceIlular immune response. As previously shown serum concentrations of neopterin are inversely correlated with blood hemoglobin concentrations in the anemia of hematological ...
Schobersberger W.   +5 more
doaj   +1 more source

EFFECT OF ERYTHROPOIETIN ON CYTOKINE PRODUCTION BY STEM CELLS

open access: yesМедицинская иммунология, 2019
Erythropoietin (EPO) is mainly used to stimulate erythropoiesis. Its cytoprotective effects upon other cells of the human body and animals were recently shown, in particular, anti-apoptotic effect was observed.
A. P. Lykov   +6 more
doaj   +1 more source

Prevention of acute kidney injury and protection of renal function in the intensive care unit : update 2017 [PDF]

open access: yes, 2017
Background: Acute kidney injury (AKI) in the intensive care unit is associated with significant mortality and morbidity. Objectives: To determine and update previous recommendations for the prevention of AKI, specifically the role of fluids, diuretics ...
Druml, W   +8 more
core   +3 more sources

Osmotically Tunable Microdroplets Enable Amplification‐Free CRISPR Detection of Gene Doping

open access: yesAdvanced Science, EarlyView.
A novel amplification‐free clustered regularly interspaced short palindromic repeats/CRISPR‐associated protein (CRISPR/Cas) 12a assay is integrated with osmotically shrinkable double emulsion droplets for the rapid and ultrasensitive detection of gene doping.
Jihun Han   +6 more
wiley   +1 more source

Erythropoietin level in normal and abnormal human seminal fluid

open access: yesАндрология и генитальная хирургия, 2021
Background. There are not enough publications devoted to the study of erythropoietin in human sperm. According to the results of these studies, the erythropoietin takes part in the regulation of spermatogenesis, affecting the synthesis of hormones, in ...
D. Yu. Sosnin   +2 more
doaj   +1 more source

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