Results 141 to 150 of about 33,348 (245)

Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation

Nature Communications, 2020
ESCRT-III complexes assemble in vivo inside membrane structures with a negative Gaussian curvature, but how membrane shape influences ESCRT-III polymerization remains unclear.
Aurélie Bertin, Nicola de Franceschi, Eugenio de la Mora, Sourav Maity, Maryam Alqabandi, Nolwen Miguet, Aurélie di Cicco, Wouter H. Roos, Stéphanie Mangenot, Winfried Weissenhorn, Patricia Bassereau   +10 more
doaj   +1 more source

Q&A: What are exosomes, exactly? [PDF]

, 2016
Exosomes are extracellular vesicles first described as such 30 years ago and since implicated in cell–cell communication and the transmission of disease states, and explored as a means of drug discovery.
Edgar, James R
core   +1 more source

Comparative Analysis of Extracellular Vesicle Isolation From Equine Serum and Plasma Using Two Isolation Methods With Structural and Proteomic Validation

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Schematic workflow of plasma‐ and serum‐derived extracellular vesicle (EV) analysis in horses, including sample preparation, EV isolation using size‐exclusion chromatography (SEC) and ultracentrifugation (UC), vesicle characterization by nanoparticle tracking analysis (NTA) and transmission electron microscopy (TEM), and comparative proteomic profiling
Dominika Milczek‐Haduch, Magdalena Żmigrodzka, Paula Kiełbik, Bianka Świderska, Jacek Olędzki, Olga Witkowska‐Piłaszewicz   +5 more
wiley   +1 more source

Identification of Human MVB12 Proteins as ESCRT-I Subunits that Function in HIV Budding [PDF]

, 2007
Eiji Morita, Virginie Sandrin, Steven L. Alam, Debra M. Eckert, Steven P. Gygi, Wesley I. Sundquist   +5 more
openalex   +1 more source

Origin of eukaryotic-like Vps23 shapes an ancient functional interplay between ESCRT and ubiquitin system in Asgard archaea [PDF]

, 2023
Zhongyi Lu, Siyu Zhang, Yang Liu, Runyue Xia, Meng Li   +4 more
openalex   +1 more source

ESCRT-I Protein Tsg101 Plays a Role in the Post-macropinocytic Trafficking and Infection of Endothelial Cells by Kaposi's Sarcoma-Associated Herpesvirus.

PLoS Pathogens, 2016
Kaposi's sarcoma-associated herpesvirus (KSHV) binding to the endothelial cell surface heparan sulfate is followed by sequential interactions with α3β1, αVβ3 and αVβ5 integrins and Ephrin A2 receptor tyrosine kinase (EphA2R).
Binod Kumar, Dipanjan Dutta, Jawed Iqbal, Mairaj Ahmed Ansari, Arunava Roy, Leela Chikoti, Gina Pisano, Mohanan Valiya Veettil, Bala Chandran   +8 more
doaj   +1 more source

Regulation of CHMP4/ESCRT-III Function in Human Immunodeficiency Virus Type 1 Budding by CC2D1A [PDF]

, 2012
Yoshiko Usami, С. В. Попов, Eric R. Weiss, Christie Vriesema-Magnuson, Arianna Calistri, Heinrich G. Göttlinger   +5 more
openalex   +1 more source

ESCRT may function as a tumor biomarker, transitioning from pan-cancer analysis to validation within breast cancer

Frontiers in Immunology
BackgroundStudies have shown that ESCRT genes affect cell aging, immune environment, and tumors. BRCA was used to explore its effects on tumor prognosis and therapy.MethodsThe data sets of Cancer Genome Atlas (TCGA), Genome-Tissue Expression Plan (GTEX),
Xiao-rui Chen, Xiao-rui Chen, Xue-ying Tan, Zong-liang Zhang, Jiang-shui Yuan, Wei-qing Song, Wei-qing Song   +6 more
doaj   +1 more source

Lem2p (LEM2) and Cmp7p (CHMP7) function in ESCRT-dependent nuclear envelope remodeling in fission yeast [PDF]

, 2016
ESCRT‐III proteins have been implicated in sealing the nuclear envelope in mammals, both during nuclear assembly and following mechanical disruption. This sealing process requires the ESCRT‐II/ESCRT‐ III hybrid protein CHMP7 and the AAA ATPase VPS4.
Bjorkman, P. J., Chen, O. S., Frost, A., Gu, M., Ladinsky, M. S., Sundquist, W. I.   +5 more
core  

Wnt-inducible Lrp6-APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway [PDF]

, 2020
Gabriele Colozza, Yasaman Jami‐Alahmadi, Alyssa Dsouza, Nydia Tejeda‐Muñoz, Lauren V. Albrecht, Eric Sosa, James A. Wohlschlegel, Edward M. De Robertis   +7 more
openalex   +1 more source