Results 141 to 150 of about 19,636 (235)
Journal of VirologyThe endosomal sorting complex required for transport (ESCRT) is a protein machine mediating membrane scission. In intraluminal vesicle (ILV) formation, ESCRT-0 targets cargoes and recruits ESCRT-I/-II to create membrane invagination, whereas ESCRT-III ...
Xiaorong Yue +5 more
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Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.Acute myeloid leukemia (AML) is a disease characterized by uncontrolled proliferation and blocked maturation of hematopoietic stem and progenitor cells. Despite progress in its clinical management, many patients continue to relapse or show limited response to standard therapies, emphasizing the need for novel, safe, and more effective targeted ...
Rongrong Hu, Zaker Ataullev, Luping Lou
wiley +1 more source
MedComm, Volume 7, Issue 8, August 2026.Mycobacterium tuberculosis–host interactions and infection outcomes. Following initial infection, alveolar macrophages phagocytose the pathogen, prompting the recruitment of innate immune cells including neutrophils, NK cells, and interstitial macrophages.
Xiaojuan Zhang +3 more
wiley +1 more source
New Phytologist, Volume 251, Issue 3, Page 1329-1343, August 2026.Overview of the results. Phylogenetic analyses of 36 assembly factors of photosystem II (PSII) and 13 proteins involved in membrane dynamics summarized in Siebenaller & Schneider (2023) were performed to investigate the taxonomic distributions and structural differences between the thylakoid‐less Gloeobacterales and the Phycobacteria. Summary Thylakoid
Louise Hambücken +2 more
wiley +1 more source
Membrane‐Associated Biomolecules for Synthetic Cell Signalling
ChemBioChem, Volume 27, Issue 13, 14 July 2026.Membrane‐associated proteins and nucleic acids are transforming synthetic cell communication, unlocking applications in biosensing, therapeutics, and tissue engineering. This review explores how these biomolecules enable complementary strategies for cell tethering, vesicle generation and fusion, signal transmission, and signal transduction.
Chelsea Dack +3 more
wiley +1 more source
Nature Cell Biology, 2020 In this issue of Nature Cell Biology, Mercier et al. show that acute changes in membrane tension may be a physiological trigger for ESCRT assembly, which drives membrane scission, luminal vesicle budding, and a wide array of other membrane remodelling events throughout the cell.
openaire +3 more sources
Genomic Tagging of Endogenous Human ESCRT-I Complex Preserves ESCRT-mediated Membrane-remodeling Functions [PDF]
, 2019 The endosomal sorting complexes required for transport (ESCRT) machinery drives membrane scission for diverse cellular functions that require budding away from the cytosol, including cell division and transmembrane receptor trafficking and degradation ...
Hoffman, Huxley K. +4 more
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NucleusThe ESCRT machinery plays a pivotal role in membrane-remodeling events across multiple cellular processes including nuclear envelope repair and reformation, nuclear pore complex surveillance, endolysosomal trafficking, and neuronal pruning.
Olivia Keeley, Alyssa N. Coyne
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Preserving Genome Integrity: Unveiling the Roles of ESCRT Machinery
CellsThe endosomal sorting complex required for transport (ESCRT) machinery is composed of an articulated architecture of proteins that assemble at multiple cellular sites. The ESCRT machinery is involved in pathways that are pivotal for the physiology of the
Mattia La Torre +2 more
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Investigating the role of the ESCRT proteins in cytokinesis [PDF]
, 2014 Endosomal sorting complex required for transport (ESCRT) proteins are conserved between Archaea, yeast and mammalian cells. ESCRT proteins mediate membrane scission events in the downregulation of ubiquitin-labelled receptors via the multivesicular body (
Bhutta, Musab Saeed
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