Results 31 to 40 of about 19,636 (235)
An ESCRT into the Endosome [PDF]
Molecular Cell, 2002 Multivesicular endosomes sort ubiquitinated membrane proteins for degradation by incorporating them into inwardly budding vesicles. The recent identification of two new oligomeric components of the sorting machinery gives us a detailed view of the complex protein-protein interactions driving this process.
openaire +2 more sources
Association of CHMP4B and autophagy with micronuclei : implications for cataract formation [PDF]
, 2014 Autophagy is a mechanism of cellular self-degradation that is very important for cellular homeostasis and differentiation. Components of the endosomal sorting complex required for transport (ESCRT) machinery are required for endosomal sorting and also ...
Nezis, Ioannis P. +2 more
core +1 more source
Multidimensional Analysis of CHMP Family Members in Hepatocellular Carcinoma
International Journal of General Medicine, 2022 Yu Guo,1 An Shang,1 Shuang Wang,2 Min Wang1 1Department of General Surgery, Jilin University Second Hospital, Changchun, Jilin, People’s Republic of China; 2Department of Dermatology, Jilin University Second Hospital, Changchun, Jilin, People’s Republic ...
Guo Y, Shang A, Wang S, Wang M
doaj
ESCRT machinery plays a role in microautophagy in yeast
BMC Molecular and Cell Biology, 2020 Background Microautophagy, which degrades cargos by direct lysosomal/vacuolar engulfment of cytoplasmic cargos, is promoted after nutrient starvation and the inactivation of target of rapamycin complex 1 (TORC1) protein kinase.
Shamsul Morshed +2 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 The endosomal sorting complex required for transport (ESCRT) is formed by ESCRT-0, ESCRT-I, ESCRT-II, ESCRT-III complexes, and accessory proteins. It conducts vesicular trafficking in eukaryotes through the formation of vesicles and membrane fission and ...
Ausencio Galindo +8 more
doaj +1 more source
Asgard ESCRT-III and VPS4 reveal conserved chromatin binding properties of the ESCRT machinery [PDF]
, 2023 The archaeal Asgard superphylum currently stands as the most promising prokaryotic candidate, from which eukaryotic cells emerged. This unique superphylum encodes for eukaryotic signature proteins (ESP) that could shed light on the origin of eukaryotes ...
Frohn, B. +12 more
core +1 more source
Resolving ESCRT-III Spirals at the Intercellular Bridge of Dividing Cells Using 3D STORM
Cell Reports, 2018 Summary: The ESCRT machinery mediates membrane fission in a variety of processes in cells. According to current models, ESCRT-III proteins drive membrane fission by assembling into helical filaments on membranes.
Inna Goliand +6 more
doaj +1 more source
ESCRT-I Protein Tsg101 Plays a Role in the Post-macropinocytic Trafficking and Infection of Endothelial Cells by Kaposi's Sarcoma-Associated Herpesvirus. [PDF]
, 2016 Kaposi's sarcoma-associated herpesvirus (KSHV) binding to the endothelial cell surface heparan sulfate is followed by sequential interactions with α3β1, αVβ3 and αVβ5 integrins and Ephrin A2 receptor tyrosine kinase (EphA2R).
Mohanan Valiya Veettil +17 more
core +1 more source
The ESCRT machinery: new roles at new holes [PDF]
, 2016 The ESCRT machinery drives a diverse collection of membrane remodeling events, including multivesicular body biogenesis, release of enveloped retroviruses and both reformation of the nuclear envelope and cytokinetic abscission during mitotic exit.
Carlton, J.G. +4 more
core +1 more source
Frontiers in Plant Science, 2011 The Endosomal Sorting Complex Required for Transport (ESCRT) consists of several multi-protein subcomplexes which assemble sequentially at the endosomal surface and function in multivesicular body (MVB) biogenesis.
Lynn eRichardson +6 more
doaj +1 more source