Results 11 to 20 of about 19,636 (235)

Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function inDrosophilaby efficient isolation of ESCRT mutants [PDF]

Journal of Cell Science, 2009
ESCRT proteins were initially isolated in yeast as a single functional set of conserved components controlling endosomal cargo sorting and multivesicular body (MVB) biogenesis. Recent work has suggested that metazoan ESCRT proteins might have more functionally diverse roles, but the limited availability of ESCRT mutants in species other than yeast has ...
T. Vaccari, T. E. Rusten, L. Menut, I. P. Nezis, A. Brech, H. Stenmark, D. Bilder   +6 more
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The ESCRT Pathway [PDF]

Developmental Cell, 2011
Multivesicular bodies (MVBs) deliver cargo destined for degradation to the vacuole or lysosome. The ESCRT (endosomal sorting complex required for transport) pathway is a key mediator of MVB biogenesis, but it also plays critical roles in retroviral budding and cytokinetic abscission.
Henne, William M., Buchkovich, Nicholas J., Emr, Scott D.   +2 more
openaire   +4 more sources

The ESCRT machinery [PDF]

Current Biology, 2012
The endosomal sorting complexes required for transport (ESCRT) assemble into a multisubunit machinery that performs a topologically unique membrane bending and scission reaction away from the cytoplasm. This evolutionarily highly conserved process is required for the multivesicular body (MVB) pathway, cytokinesis and HIV budding.
Schmidt, Oliver, Teis, David
openaire   +4 more sources

AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody. [PDF]

PLoS Genetics, 2021
To complete mitosis, the bridge that links the two daughter cells needs to be cleaved. This step is carried out by the endosomal sorting complex required for transport (ESCRT) machinery. AKTIP, a protein discovered to be associated with telomeres and the
Chiara Merigliano, Romina Burla, Mattia La Torre, Simona Del Giudice, Hsiangling Teo, Chong Wai Liew, Alexandre Chojnowski, Wah Ing Goh, Yolanda Olmos, Klizia Maccaroni, Maria Giubettini, Irene Chiolo, Jeremy G Carlton, Domenico Raimondo, Fiammetta Vernì, Colin L Stewart, Daniela Rhodes, Graham D Wright, Brian E Burke, Isabella Saggio   +19 more
doaj   +3 more sources

Dynamic Association of ESCRT-II Proteins with ESCRT-I and ESCRT-III Complexes during Phagocytosis of Entamoeba histolytica [PDF]

International Journal of Molecular Sciences, 2023
By their active movement and voraux phagocytosis, the trophozoites of Entamoeba histolytica constitute an excellent system to investigate the dynamics of the Endosomal Sorting Complex Required for Transport (ESCRT) protein interactions through phagocytosis. Here, we studied the proteins forming the E. histolytica ESCRT-II complex and their relationship
Mitzi Díaz-Hernández, Rosario Javier-Reyna, Diana Martínez-Valencia, Sarita Montaño, Esther Orozco   +4 more
openaire   +3 more sources

ESCRT-I Part II: Forming the Real ESCRT-I Complex [PDF]

Cell Host & Microbe, 2007
Many enveloped viruses hijack the cellular ESCRT machinery to catalyze their escape from host cells. One paper in a recent issue of Cell by Kostelansky et al. and another in this issue of Cell Host & Microbe by Morita et al. shed new light on the structure and function of ESCRT-I. Both papers focus on a fourth ESCRT-I component that shapes ESCRT-I into
Weissenhorn, Winfried, Göttlinger, Heinrich   +1 more
openaire   +4 more sources

ESCRT Requirements for Murine Leukemia Virus Release [PDF]

Viruses, 2016
The Murine Leukemia Virus (MLV) is a gammaretrovirus that hijack host components of the endosomal sorting complex required for transport (ESCRT) for budding.
Christina Bartusch, Reinhild Prange
doaj   +2 more sources

Diversity, origin, and evolution of the ESCRT systems [PDF]

mBio
Endosomal sorting complexes required for transport (ESCRT) play key roles in protein sorting between membrane-bounded compartments of eukaryotic cells.
Kira S. Makarova, Victor Tobiasson, Yuri I. Wolf, Zhongyi Lu, Yang Liu, Siyu Zhang, Mart Krupovic, Meng Li, Eugene V. Koonin   +8 more
doaj   +2 more sources

A relay race of ESCRT-III paralogs drives cell division in a hyperthermophilic archaeon [PDF]

mBio
Cell division is a fundamental process ensuring the perpetuation of all cellular life forms. Archaea of the order Sulfolobales divide using a simpler version of the eukaryotic endosomal sorting complexes required for transport (ESCRT) machinery, composed
Junfeng Liu, Mickaël Lelek, Yunfeng Yang, Audrey Salles, Christophe Zimmer, Yulong Shen, Mart Krupovic   +6 more
doaj   +2 more sources

ESCRT-II role in cell biology, development and disease [PDF]

, 2023
Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the Department of Microbiology, School of Life Sciences, Faculty of Science, Technology and Engineering, La Trobe University, Bundoora ...
Ilievska, Jasmina (14373663)
core   +3 more sources