Results 171 to 180 of about 4,462 (212)
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Microdetermination of esculetin in Nicotiana tabacum
Analytical Biochemistry, 1973Abstract A glc method has been described for the quantitative analysis of tobacco (and other plant tissue) for esculetin (as free esculetin and the glucosides esculin or cichoriin) which used tritium-foil electron-capture detection of as little as 15 ng esculetin.
T H, Vaughn, R A, Andersen
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Selective inhibition of platelet lipoxygenase by esculetin
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1982The effects of coumarin and its derivatives on rat platelet lipoxygenase and cyclooxygenase activities were studied. Esculetin (6,7-dihydroxycoumarin) was found to inhibit the lipoxygenase more strongly than the cyclooxygenase; its concentration for 50% inhibition (IC50) was 0.65 microM for platelet lipoxygenase and 0.45 mM for platelet cyclooxygenase.
K, Sekiya, H, Okuda, S, Arichi
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ESCULETIN PREVENTS LIVER DAMAGE INDUCED BY PARACETAMOL AND CCL4
Pharmacological Research, 1998Esculetin, a phenolic compound found in Cichorium intybus and Bougainvllra spectabillis was investigated for its possible protective effect against paracetamol and CCl4-induced hepatic damage. Paracetamol produced 100% mortality at the dose of 1 g kg-1 in mice while pre-treatment of animals with esculetin (6 mg kg-1) reduced the death rate to 40%. Oral
Gilani, A H, Janbaz, K H, Shah, B H
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Induction of apoptosis by esculetin in human leukemia cells
European Journal of Pharmacology, 2001Esculetin, a coumarin compound, has been shown to exhibit antioxidant and anti-inflammatory effects. In the present study, esculetin was found to inhibit the survival of human promyelocytic leukemia HL-60 cells in a concentration-dependent and time-dependent manner.
C Y, Chu +4 more
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Conversion of Caffeic Acid to Esculetin during Paper Chromatography
Nature, 1959ESCULETIN was found in an extract of plant tissue which contained caffeic acid. The esculetin was not a natural product but was formed from caffeic acid during the paper-chromatographic purification procedures. This conversion was confirmed by two-dimensional chromatography of authentic caffeic acid.
W L, BUTLER, H W, SIEGELMAN
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Esculetin induces mitochondria-mediated apoptosis in 3T3-L1 adipocytes
Apoptosis, 2006Adipose tissue mass is determined by the volume and the number of adipocytes and is subjected to homeostatic regulation involving cell death mechanisms. We investigated the effects of esculetin, a coumarin compound, on apoptotic signaling in 3T3-L1 adipocytes.
Jeong-Yeh, Yang +2 more
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Glucosylation of esculetin by plant cell suspension cultures
Plant Cell, Tissue and Organ Culture, 1984Cell suspension cultures of Lithospermum erythrorhizon, Gardenia jasminoides and Nicotiana tabacum were capable of glucosylating esculetin to esculin (7-hydroxycoumarin-6-O-β-D-glucoside). Especially, a culture strain of Lithospermum erythrorhizon was superior in the esculetin glucosylating capability; 40 to 50% of esculetin administered to the culture
M. Tabata +3 more
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ChemInform Abstract: Improved Synthesis of Esculetin.
ChemInform, 1995AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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Electrochemical Behavior of Esculetin on Glassy Carbon Electrode
ECS Transactions, 2010The electrochemical behavior of esculetin was investigated by cyclic voltammetry on glassy carbon electrode. The experimental conditions, such as supporting electrolyte and pH value, were tested for the electrochemical characterization of esculetin. It was shown that, in acetate buffer, the electrochemical behavior of esculetin had good reversibility.
Yatao Chen +5 more
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Protective effects of esculetin against ovary ischemia–reperfusion injury model in rats
Journal of Biochemical and Molecular Toxicology, 2023AbstractAimsOvarian ischemia–reperfusion (I/R) injury is a phenomenon that necessitates urgent intervention, which occurs as a result of ovarian torsion, and it is frequently seen in young women. A large amount of free radical and oxidative damage as a result of I/R plays a role in the cause of the incident.
Mehmet Güvenç +5 more
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