Results 81 to 90 of about 4,462 (212)
This study investigates the phenolic profile, antioxidant capacity, antimicrobial effect, and antihemolytic activity of nettle leaves from Algerian species Urtica pilulifera and Urtica urens. Results show high levels of flavonoids, tannins, alkaloids, and terpenoids in the extracts.
Hasna Bouhenni +8 more
wiley +1 more source
Antiplatelet Activity of Coumarins: In Vitro Assays on COX-1
Atherosclerotic cardiovascular disease is the leading cause of death in developed countries. Therefore, there is an increasing interest in developing new potent and safe antiplatelet agents.
Cristina Zaragozá +3 more
doaj +1 more source
腸内菌由来Arylsulfate Sulfotransferaseに関する生化学的研究 [PDF]
硫酸抱合反応は,種々の水酸基を有する化合物の解毒の主な経路である。この硫酸化を触媒する酵素としてsulfotransferaseが知られており,この酵素は,arylamine,phenol,steroidやbile acidなどの基質の違いにより分類されている。この酵素は硫酸基を3\u27-phosphoadenosine-5\u27-phosphosulfate(PAPS)からアルコール性あるいはフェノール性水酸基に転移する反応を触媒する。最近,同様な酵素が植物,Flaveriaからも見つかっている ...
今村 理佐
core +1 more source
Endophytic fungi of P. auritum were evaluated for their ability to produce inhibitors of formation of advanced glycation end products (AGEs). Neopestalotiopsis sp. H2 and Diaporthe sp. H5 extracts were the most active. So, we performed their chemical profiling by untargeted and phenolics‐targeted metabolomic approaches to identify the potential ...
Lory Sthephany Rochín‐Hernández +3 more
wiley +1 more source
Oxidative stress-induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease [PDF]
BackgroundInflammation and oxidative stress play critical roles in patients with chronic obstructive pulmonary disease (COPD). Mitochondrial oxidative stress might be involved in driving the oxidative stress–induced pathology.ObjectiveWe sought to ...
Vestbo +46 more
core +1 more source
JAE demonstrates potent antioxidant activity and protects against radiation‐induced lung injury. Proteomic reveals JAE modulates apoptosis and oxidative stress pathways for radioprotection. JAE demonstrates broad cellular protection against UVC damage in lung and skin cell models.
Liping Wang +5 more
wiley +1 more source
Esculetin reduces leukotriene B4 level in plasma of rats with adjuvant-induced arthritis
Objectives : Esculetin (6,7-dihydroxycoumarin) is a natural coumarin with anti-oxidant, anti-inflammatory and anti-nociceptive activity. It acts as a potent inhibitor of lipoxygenases (5-LOX and 12-LOX) and decreases the production of matrix ...
Przemysław Rzodkiewicz +5 more
doaj +1 more source
An Efficient Methodology for the Synthesis of 3-Styryl Coumarins [PDF]
Regioselective and highly efficient Heck arylation of 3-vinyl-6,7-dimethoxycoumarin has been developed to afford 3-styryl coumarins in good to very high yields. The increase in conjugation reflects on the absorbance of the synthesized compounds revealing
Martins, Branco, P. S.
core
Composition variation in essential oils of Artemisia nilagirica and Artemisia capillaris, growing in India [PDF]
The present study was aimed to find out the chemical constituents of essential oils of Artemisia nilagirica (Clarke) Pamp. and Artemisia capillaris Thunb. of Asteraceae family, growing in Garhwal region of India. The essential oils were obtained by hydro-
Badoni, Ruchi +2 more
core +2 more sources
Macrophage GHSR‐Foxo1 axis regulates CCl4‐induced liver fibrosis by promoting inflammation and TGF‐β1‐mediated HSC activation. GHSR activates PKA‐dependent phosphorylation of Foxo1 at serine 273, promoting macrophage pro‐inflammatory polarization to enhance the production of pro‐inflammatory cytokines that damage hepatocytes, thereby inducing liver ...
Da Mi Kim +9 more
wiley +1 more source

