Results 61 to 70 of about 141,634 (350)

High survivin expression as a risk factor in patients with anal carcinoma treated with concurrent chemoradiotherapy [PDF]

, 2012
Purpose: To investigate the prognostic value of survivin expression in pretreatment specimens from patients with anal cancer treated with concurrent 5-FU and mitomycin C-based chemoradiation (CRT).
Distel, Luitpold Valentin Rudolf, Falk, Stefan, Fraunholz, Ingeborg, Kohler, Daniela, Rave-Fränk, Margret, Rödel, Claus, Rödel, Franz   +6 more
core   +2 more sources

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

Advanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu, Yingjie Dong, Jianghui Tong, Jingxuan Xia, Longhao Zhao, Zi Geng, Yingxin Lin, Jinghe Zhang, Xinyi Liu, Manqi Fang, Xi Jin, Yujing Bi, Guangwei Liu   +12 more
wiley   +1 more source

Biomass fuel as a risk factor for esophageal squamous cell carcinoma: a systematic review and meta-analysis

Environmental Health, 2019
Background The link between use of solid biomass fuel (wood, charcoal, coal, dung, and crop residues) for cooking and/or heating and esophageal squamous cell carcinoma (ESCC) is inconclusive.
Samson Okello, Suzan Joan Akello, Emmanuel Dwomoh, Emmanuel Byaruhanga, Christopher Kenneth Opio, Ruyang Zhang, Kathleen E. Corey, Winnie R. Muyindike, Ponsiano Ocama, David D. Christiani   +9 more
doaj   +1 more source

Difference in Intestinal Flora Among Patients with Esophageal Squamous Cell Carcinoma and Normal Population

Zhongliu Fangzhi Yanjiu, 2023
Objective To investigate the difference in intestinal flora among patients with esophageal squamous cell carcinoma and normal population and to provide a basis for the early diagnosis of esophageal squamous cell carcinoma as a marker.
CAO Yanzhen, TUSUNAYI·Wumaier, HU Jiajie, YANG Lili, FANG Xinzhi   +4 more
doaj   +1 more source

Clinical significance of VEGF-A, -C and -D expression in esophageal malignancies [PDF]

, 2005
Vascular endothelial growth factors ( VEGF)- A, - C and - D are members of the proangiogenic VEGF family of glycoproteins. VEGF-A is known to be the most important angiogenic factor under physiological and pathological conditions, while VEGF-C and VEGF-D
Ahn MJ, Baatar D, Banks RE, Berse B, Boucher Y, Coia LR, Dirix LY, Du JR, Gu ZP, Guo WZ, Hefler L, Hickey K, Hironaka S, Isaka N, Ishikawa M, Karpanen T, Kato H, Kitadai Y, Kitamura K, Koide N, Koukourakis MI, Kukk E, Kumar H, Lackey VL, Lewis CE, Li Z, Maniwa Y, Millikan KW, Mobius C, Nagata J, Nguyen M, Noguchi T, Nor JE, Ohtsu A, Roberts WG, Rockwell S, Roder JD, Salven P, Shih CH, Spence GM, Suit HD, Theunissen PH, Uchida S, Vogel SB, Wallner G, Weingartner K, Yamamoto Y, Yang B, Yeo KT   +48 more
core   +1 more source

PDIA3 Inhibition Facilitates Sensitivity of IKE‐Induced Ferroptosis via STAT3/LCN2 Axis to Improve Glioblastoma Therapy

Advanced Science, EarlyView.
In this manuscript, protein disulfide isomerase A3 (PDIA3) is identified as a key factor mediating the susceptibility of ferroptosis in GBM. Inhibition of PDIA3 enhances IKE or cystine starvation‐induced ferroptosis in GBM cells by resulting in the accumulation of lipid peroxidation and a reduction in GSH level.
Jie Zhang, Wei Wang, Xin Liu, Peifen Lu, Xinjing Liu, Qiucheng Nie, Siyuan Xin, Hong Li, Donglin Yu, Xinyue Zhang, Kailong Li, Xiaomin Han, Shuping Zhang, Wei Chong, Lili Sun, Wei Li, Tao Xin, Jin Jiao, Qiang Ma, Yiju Wei   +19 more
wiley   +1 more source

The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer. [PDF]

, 2016
A better understanding of the dynamics of molecular changes occurring during the early stages of oral tumorigenesis may help refine prevention and treatment strategies.
Bertolus, Chloé, Caulin, Carlos, Chabaud, Sylvie, Foy, Jean-Philippe, Goudot, Patrick, Hong, Waun Ki, Lachuer, Joël, Lang, Wenhua, Lavergne, Emilie, Le Texier, Vincent, Lippman, Scott M, Perol, David, Saintigny, Pierre, Thomas, Emilie, Tortereau, Antonin   +14 more
core   +1 more source

Spatio‐Temporal Proteomic Landscape Reveals Early Warning Signals of Esophageal Squamous Cell Carcinoma Progression

Advanced Science, EarlyView.
This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li, Jie Yuan, Min Gao, Jibin Liu, Qinqin Wang, Yaqi Zhang, Mingtao Cao, Xiaolin Hu, Hui Yang, Jun Li, Chen Li, Xiaoguang Li, Hui Wang   +12 more
wiley   +1 more source

The significance of CD4+ and CD8+ T lymphocyte infiltration in esophageal squamous cell carcinoma

Indian Journal of Pathology and Microbiology
Purpose: To investigate the relationship between the abundance of CD4+ and CD8+ T cells in the tumor microenvironment and the prognosis of patients with esophageal squamous cell carcinoma, and to analyze their correlation and explore its clinical value ...
Jiang Y. Zhao, Xiaojun Pang, Jiao Peng, Jingtao Liu, Qiang Deng, Shunhai Jian   +5 more
doaj   +1 more source

Impact of Radiotherapy, Chemotherapy and Surgery in Multimodal Treatment of Locally Advanced Esophageal Cancer [PDF]

, 2011
Objectives: It was the aim of this study to assess our institutional experience with definitive chemoradiation (CRT) versus induction chemotherapy followed by CRT with or without surgery (C-CRT/S) in esophageal cancer.
Adams R, Annina Lemminger, Bedenne L, Berger B, Bernhard Berger, Claus Belka, Cooper JS, Delcambre C, Denham JW, Herskovic A, Katharina Stahlberg, Malthaner RA, Martin Bleif, Michael Bamberg, Minsky BD, Mizumoto M, Rades D, Sarraf M, Seung SK, Shi XH, Stahl M, Tepper J, Wolf M, Zhang Z   +23 more
core   +1 more source