Results 41 to 50 of about 378,407 (392)

Delineating the early transcriptional specification of the mammalian trachea and esophagus

eLife, 2020
The genome-scale transcriptional programs that specify the mammalian trachea and esophagus are unknown. Though NKX2-1 and SOX2 are hypothesized to be co-repressive master regulators of tracheoesophageal fates, this is untested at a whole transcriptomic ...
Akela Kuwahara, Ace E Lewis, Coohleen Coombes, Fang-Shiuan Leung, Michelle Percharde, Jeffrey O Bush   +5 more
doaj   +1 more source

Multiple myeloma with esophageal involvement: A rare case

DEN Open, 2022
A 77‐year‐old man presented with a spinal cord tumor at the cervical 7/thoracic 1 level and pain and weakness in the right hand. Blood tests revealed anemia, renal dysfunction, and hyperproteinemia.
Misako Tohata, Yorimasa Yamamoto, Hiroshi Harada, Erika Yoshida, Yuichi Takano, Kuniyo Gomi, Masatsugu Nagahama, Hiroshi Takahashi   +7 more
doaj   +1 more source

Alterations to the Esophageal Microbiome Associated with Progression from Barrett's Esophagus to Esophageal Adenocarcinoma

Cancer Epidemiology, Biomarkers and Prevention, 2019
Background: The incidence of esophageal adenocarcinoma has risen dramatically over the past half century, and the underlying reasons are incompletely understood. Broad shifts to the upper gastrointestinal microbiome may be partly responsible. The goal of
Erik J. Snider, Griselda Compres, D. Freedberg, Hossein Khiabanian, Y. Nobel, Stephania Stump, A. Uhlemann, C. Lightdale, J. Abrams   +8 more
semanticscholar   +1 more source

Risk factors and prediction models for severe radiation-induced oral mucositis in patients with nasopharyngeal carcinoma undergoing chemoradiotherapy

Discover Oncology
Objective This study aimed to investigate the factors associated with severe radiation-induced oral mucositis (SRIOM) in nasopharyngeal carcinoma (NPC) patients undergoing chemoradiotherapy (CRT) and to establish a prediction model for SRIOM.
Yi Liang, XiaoQin Wang, XunRen Shi, XinXiong Fei   +3 more
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Incidence of adenocarcinoma among patients with Barrett's esophagus.

New England Journal of Medicine, 2011
BACKGROUND Accurate population-based data are needed on the incidence of esophageal adenocarcinoma and high-grade dysplasia among patients with Barrett's esophagus.
F. hvid-Jensen, L. Pedersen, A. Drewes, H. Sørensen, P. Funch-Jensen   +4 more
semanticscholar   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Substance use and esophageal neuroendocrine neoplasm: A case–control study

Kaohsiung Journal of Medical Sciences, 2022
Esophageal neuroendocrine neoplasms (NEN) are extremely rare and little is known about their risk factors. To identify the potential risk factors, we evaluated whether the history of substance use, including alcohol, tobacco and areca nut consumption was
Yao‐Kuang Wang, Hsiang‐Yao Shih, Yin‐Yi Chu, Chao‐Hung Kuo, Yi‐Hsun Chen, Chen‐Shuan Chung, Cho‐Lun Tsai, Jung‐Chun Lin, Hsiu‐Po Wang, I‐Chen Wu   +9 more
doaj   +1 more source

Radiofrequency ablation in Barrett's esophagus with dysplasia.

New England Journal of Medicine, 2009
BACKGROUND Barrett's esophagus, a condition of intestinal metaplasia of the esophagus, is associated with an increased risk of esophageal adenocarcinoma.
N. Shaheen, Prateek Sharma, B. Overholt, H. Wolfsen, R. Sampliner, Kenneth K Wang, J. Galanko, M. Bronner, J. Goldblum, A. Bennett, B. Jobe, G. Eisen, M. Fennerty, J. Hunter, D. Fleischer, V. Sharma, R. Hawes, B. Hoffman, R. Rothstein, S. Gordon, H. Mashimo, K. Chang, V. Muthusamy, S. Edmundowicz, S. Spechler, A. Siddiqui, R. Souza, A. Infantolino, G. Falk, M. Kimmey, R. Madanick, A. Chak, C. Lightdale   +32 more
semanticscholar   +1 more source

The esophagogastric junctional adenocarcinoma an increasing disease [PDF]

, 2017
Identifying and defining the esophagogastric junctional adenocarcinoma (EGJA) as an independent disease apart from gastric cancer (GC) and esophagus cancer (EG) it has always been a difficult issue entailing doubts about the appropriate therapeutic ...
Andreetti, Claudio, Ibrahim, Mohsen, Menna, Cecilia, Pastina, Monica   +3 more
core   +1 more source