Integrative transcriptomic profiling reveals subtype-specific therapeutic vulnerabilities and resistance mechanisms in prostate cancer. [PDF]
Liu W +10 more
europepmc +1 more source
International meeting: new diagnostic tests are urgently needed to treat patients with Chaga's disease [PDF]
Campaign for Access to Essential Medicines +1 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Acaricidal and synergistic activity of essential oils, their binary combinations, and nanoemulsions against larvae and unfed adult stages of brown dog tick Rhipicephalus sanguineus (Acari: Ixodidae). [PDF]
Abdel-Ghany HSM +5 more
europepmc +1 more source
Developing 21st Century Essential Life Skills: Supporting self-regulation in 3-4 year olds [PDF]
Barbour, Laura
core
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
How the MDGs gave up on measuring access to medicines
Dzintars Gotham +2 more
doaj +1 more source
Chemical Profiling and Multimodal Anti-Inflammatory Activity of <i>Eugenia pyriformis</i> Leaves Essential Oil. [PDF]
Ribeiro LS +10 more
europepmc +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Antifungal effects of essential oils on the preservation of historical monuments: A sustainable approach. [PDF]
Acar HY, Sert HB.
europepmc +1 more source

