Results 131 to 140 of about 2,035,370 (389)
The effect of supplementation of essential amino acid combinations in a low crude protein diet on growth performance in weanling pigs [PDF]
Michael O Wellington +5 more
openalex +1 more source
Purpose of Review: Sarcopenia (skeletal muscle wasting with aging) is thought to underlie a number of serious age-related health issues. While it may be seen as inevitable, decreasing this gradual loss of muscle is vital for healthy aging.
Hayes, Alan, Cribb, Paul J
core
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Background/Objectives: The quality and composition of dietary proteins are crucial during growth, particularly in children who follow vegetarian diets. Branched-chain amino acids (BCAAs: leucine, isoleucine, and valine) and lysine play essential roles in
Jadwiga Ambroszkiewicz +6 more
core +1 more source
Essential amino acids of the prawn.
The essential amino acids of the prawn Penaeus japonicus were investigated by a radio-isotopic method using [3H] acetate, the incorporation of radioactivity into the constituent amino acids of protein fraction was examined by column chromatography on Amberlite IR-120, followed by the radioactivity measurement.
KANAZAWA, Akio, TESHIMA, Shin-ichi
openaire +2 more sources
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Silicon-induced root nodulation and synthesis of essential amino acids in a legume is associated with higher herbivore abundance [PDF]
Ecologists have become increasingly aware that silicon uptake by plants, especially the Poaceae, can have beneficial effects on both plant growth and herbivore defence.
Frew, Adam +22 more
core +1 more source
Background: Amino acids and cell Ca2+ are potent regulators of autophagy that are thought to act independently of each other. Results: Withdrawal of essential amino acids increases cytosolic Ca2+ and subsequently activates autophagy via a CaMKK-β-AMPK ...
G. Ghislat +3 more
semanticscholar +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Essential amino-acids of some tropical cereal millets [PDF]
N. G. Baptist, B. P. M. Perera
openalex +1 more source

