Results 51 to 60 of about 1,230,897 (338)
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
LA PROBLÉMATIQUE DE L’EFFECTIVITÉ DE L’ACTION PUBLIQUE EN DROIT DU TRAVAIL CONGOLAIS [PDF]
Cahiers Africains des Droits de l’Homme et de la Démocratie ainsi que du Développement Durable, 2022 Le code du travail mentionne les infractions du travail. Mais le législateur n’a ni organisé la procédure applicable pour l’infliction de la peine ni la juridiction compétente.
André VANGU MAKUALA
doaj
Selective Nitro Reduction of Ester Substituted Nitroarenes by NaBH4-FeCl2
Pharmaceutical Fronts, 2022 This work aimed to explore a novel protocol for selective reduction of the nitro group on the aromatic ring while remaining the ester group unaffected. In this study, NaBH4-FeCl2 was disclosed as a key reductant in the process.
Zi-Hong Zhou +5 more
doaj +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2015 The title compound, C14H15FN2O2S, crystallizes with two molecules in the asymmetric unit. In each molecule, the pyrimidine ring adopts a sofa conformation with the sp3-hybridized C atom forming the flap and the fluoro-substituted ring in an axial ...
M. S. Krishnamurthy, Noor Shahina Begum
doaj +1 more source
Phthalate esters: occurrence, toxicity, bioremediation, and advanced oxidation processes [PDF]
, 2023 Madhu Kumari, Mrudula Pulimi
openalex +1 more source
A Comparative Study of Physicochemical, Dielectric and Thermal Properties of Pressboard Insulation Impregnated with Natural Ester and Mineral Oil [PDF]
, 2011 Natural ester is considered to be a substitute of mineral oil in the future. To apply natural ester in large transformers safely, natural ester impregnated solid insulation should be proved to have comparable dielectric strength and thermal stability to ...
Chen, George +4 more
core +1 more source
Advanced Functional Materials, EarlyView.PBTTT‐OR‐R, a C14‐alkoxy/alkyl‐PBTTT polymer derivative, is of substantial interest for optoelectronics due to its specific fullerene intercalation behavior and enhanced charge‐transfer absorption. Comparing this polymer with (S) and without (O) homocoupling defects reveals that PBTTT‐OR‐R(O) forms stable co‐crystals with PC61BM, while PBTTT‐OR‐R(S ...
Zhen Liu +14 more
wiley +1 more source