Results 91 to 100 of about 39,453 (284)
FEBS Letters, 1983 A non‐specific esterase activity of hen lysozyme (c‐type) has previously been described: histidine was claimed to be involved in this activity. The present letter reports that a histidine‐less lysozyme from the duck egg‐white (c‐type) as well as a goose lysozyme (g‐type) possess such an esterase activity determined using p‐nitrophenylacetate.
Jollès, Jacqueline, Jollès, Pierre
openaire +2 more sources
Sensing and Degradation of Organophosphorus Compounds by Exploitation of Heat-Loving Enzymes
ChemosensorsThe increasing incidence of organophosphate (OP) pesticide poisoning and the use of OP chemical warfare agents (CWA) in conflicts and terrorist acts need sustainable methods for sensing, decontamination, and detoxification of OP compounds.
Giuseppe Manco +5 more
doaj +1 more source
Application of regio-selective esterases to nucleoside modification. [PDF]
Six esterases, PCLD420CE1, PCLD1E1, PETase075, PCLD3E2, PCLDK29_3, PCLD5BE1, were analysed in this work, which were selected from ground samples after preparation of metogenomic or genomic libraries by scientists of the Department of Molecular ...
Čekanauskas, Kipras,
core
Comparative In silico Analysis of Enzymatic Degradation Resistance in Resin-matrix Ceramics
Biomedical and Biotechnology Research JournalBackground: Resin-matrix ceramics (RMCs) are commonly used in prosthetic dentistry due to their ability to closely replicate the optical and mechanical characteristics of natural teeth.
Özay Önöral +2 more
doaj +1 more source
Trimethyl Lock: A Stable Chromogenic Substrate for Esterases
, 2008 p-Nitrophenyl acetate is the most commonly used substrate for detecting thecatalytic activity of esterases, including those that activate prodrugs in human cells. Thissubstrate is unstable in aqueous solution, limiting its utility.
Luke D. Lavis +2 more
core +1 more source
Safety and pharmacokinetics of inhaled aloxistatin: A first‐in‐human phase 1 dose escalation trial
British Journal of Clinical Pharmacology, EarlyView.Aims Aloxistatin (E64d) is a membrane‐permeable cysteine protease inhibitor prodrug that is converted by esterases to the active metabolite E64c (loxistatin). This first‐in‐human study evaluated the safety, tolerability and pharmacokinetics of single ascending doses of inhaled E64d in healthy volunteers.
Sebastian Fähndrich +24 more
wiley +1 more source
Novel esterases and uses thereof
, 2022 The present invention relates to novel esterase, more particularly to esterase variants having improved thermostability compared to the esterase of SEQ ID No 1 and the uses thereof for degrading polyester containing material, such as plastic products ...
André, Isabelle +7 more
core +1 more source
Feruloyl esterases - Evaluation of their potential for biotechnological applications [PDF]
, 2019 Owing to the current efforts to find sustainable alternatives to petrochemical based industries and technologies, enzymatic degradation and valorization of plant biomass has been attracting interest.
Bonzom, Cyrielle
core
British Journal of Clinical Pharmacology, EarlyView.Aim This study aimed to describe the pharmacokinetics (PK) of levetiracetam (LEV) in term neonates treated for neonatal seizures secondary to hypoxic–ischemic encephalopathy (HIE). Methods Fifteen neonates were included and received a loading dose ranging from 30 to 60 mg/kg followed by eight maintenance doses corresponding to one‐fourth of the loading
Léo Mimram +9 more
wiley +1 more source