Results 111 to 120 of about 119,219 (330)
Factors associated to Amblyomma variegatum presence on farms in Nevis and determination of high risks TBR areas [PDF]
, 2012 Tropical Bont Tick (TBT), Amblyomma variegatum, is an invasive tick species of ruminants present in 10 Caribbean islands. TBT and the associated disease dermatophilosis, have been a challenge to livestock development in Nevis, Northern West Indies, for ...
Alfred, S. +9 more
core
ProTides for Antiviral Activity Beyond Liver Cells
Chemistry – A European Journal, EarlyView.A strategy for obtaining prodrugs of antiviral nucleotides with broad tissue activity is presented that relies on cycloalkyl or cycloalkylalkyl esters, improving uptake and esterase cleavage, and producing nanomolar inhibitors in kidney, colon, and lung cells.
Felix Goebel +5 more
wiley +1 more source
Journal of Vector Borne Diseases, 2017 Background & objectives: Increase in prevalence and intensity of insecticide-resistance in vectors of vector-borne diseases is a major threat to sustainable disease control; and, for their effective management, studies on resistance mechanisms are ...
Kona Madhavinadha Prasad +4 more
doaj +1 more source
Esterases computational study [PDF]
, 2017 In our project, we are focusing on two different esterases called LAE6 and LAE5. LAE6 is very promiscuous since it presents activity towards a wide range of different substrates, whereas LAE5 presents activity towards few substrates. This promiscuity can
Cañadas, Ruben +2 more
core
Cancer Nexus, EarlyView.ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han +5 more
wiley +1 more source
Revista Colombiana de Biotecnología, 2010 Las lipasas son enzimas con propiedades funcionales muy interesantes que permiten su utilización práctica en diversos campos de las industrias agroquímica, farmacéutica, de detergentes y alimentaria, así como en química fina.
Jorge González-Bacerio +2 more
doaj +2 more sources
Sensing and Degradation of Organophosphorus Compounds by Exploitation of Heat-Loving Enzymes
ChemosensorsThe increasing incidence of organophosphate (OP) pesticide poisoning and the use of OP chemical warfare agents (CWA) in conflicts and terrorist acts need sustainable methods for sensing, decontamination, and detoxification of OP compounds.
Giuseppe Manco +5 more
doaj +1 more source
Acta Scientiarum: Biological Sciences, 2012 Total proteins and esterases from silk gland extracts of Bombyx mori silkworm were characterized and compared with electrophoretic profiles of prepared extracts with silkworm glands infected with nucleopolyhedrovirus (BmNPV).
Juliana Bueno Ruiz +3 more
doaj +1 more source
Environmental Toxicology and Chemistry, EarlyView.Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers +10 more
wiley +1 more source