Results 71 to 80 of about 39,453 (284)
Advanced Science, EarlyView.A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song +6 more
wiley +1 more source
Angewandte Chemie, EarlyView.A meso‐carboxamide‐substituted BODIPY fluorescent probe reports myeloperoxidase (MPO) activity via electrophilic chlorination by MPO‐derived HOCl, generating a highly emissive chlorinated product with a ca. 40 nm bathochromic shift. Applications in quantitative MPO assays, cellular imaging of MPO‐derived HOCl, redox‐dependent discrimination of cancer ...
Siyoung Cho +3 more
wiley +2 more sources
Invertebrate Survival Journal, 2014 Biochemical biomarkers and bioassays, due to their assumed immediate response after acute exposure of the organism to the stressor, are useful tools to gauging anthropogenic impacts. The toxicity of TiO2-nanoparticles (TiO2-NPs) on the Glyphodes pyloalis
N Memarizadeh +3 more
doaj
Acta Biológica Colombiana, 2014 Despite the condition of leaf-cutting ant pests in agroecosystems, it is undeniable the benefits they can bring in certain situations or environments.
Liriana Belizário Cantagalli +3 more
doaj +1 more source
Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2
Advanced Science, EarlyView.Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang +15 more
wiley +1 more source
, 2003 Discussed are the pectin esterases. They comprise enzymes that hydrolyze the esters present in the pectin backbone. Currently three classes of esterases have been identified: the pectin methylesterases, the pectin acetylesterases and the ...
Alebeek, G.J.W.M., van +3 more
core
SEPARATION AND RELATIVE QUANTITATION OF MOUSE PLASMA ESTERASES WITH DISC ELECTROPHORESIS
, 1965 A technique for the qualitative and quantitative study of mouse plasma esterases using disc electrophoresis in acrylamide gel is described. This technique has been employed to study substrate specificity and quantitative relationships among various ...
R. C. ALLEN, D. J. MOORE, R. A. POPP
core +1 more source
Advanced Science, EarlyView.A dual‐transmembrane Bicephali CAR‐T platform simultaneously targets CD276 and NKG2D ligands to address antigen heterogeneity in non‐small cell lung cancer. By improving immune synapse formation, mitochondrial fitness, antioxidant capacity, and stem‐like persistence, this design enhances durable tumor control and provides a versatile strategy to ...
Lina Wang +8 more
wiley +1 more source
Classification and Catalytic Properties of Esterases Reacting with Organophosphorus Compounds [PDF]
, 1995 The classification, molecular structure and substrate specificity of serine esterases and phosphoric triester hydrolases is described. Human serum cholinesterase (EC 3.1.1.8) and paraoxonase (EC 3.1.8.1) are described in more detail.
Reiner, Elsa +2 more
core +1 more source
Memorias do Instituto Oswaldo Cruz, 2009 In order to establish the insecticide susceptibility status for Anopheles darlingi in Colombia, and as part of the National Network on Insecticide Resistance Surveillance, five populations of insects from three Colombian states were evaluated ...
Idalyd Fonseca-González +3 more
doaj +1 more source