Results 71 to 80 of about 8,065 (240)

Modulating Calcium Homeostasis via a Biomimetic Scaffold to Rescue Diabetic Ischemic Wounds

open access: yesAdvanced Science, EarlyView.
This strategy addresses impaired microcirculation and loss of extracellular matrix (ECM) guidance in diabetic wound healing. Musc@CP, a nanofibrous dressing combining an ECM‐mimetic chitosan‐pullulan scaffold with muscone, enhances perfusion by attenuating intracellular Ca2+ overload‐associated endothelial dysfunction.
Xiang Zheng   +14 more
wiley   +1 more source

Human Foetal Neuroblasts Exhibit BK Channel‐Dependent Membrane Voltage Oscillations upon Depolarization

open access: yesAdvanced Science, EarlyView.
Primary cultures of neuroblasts isolated from the nucleus basalis of Meynert of 12‐weeks‐old human foetuses were prepared. Whole‐cell patch‐clamp recordings were performed by injecting a depolarizing stimulus current (+500 pA; 500 ms), and the membrane voltage recorded; this stimulus current evoked periodic‐like oscillations in membrane voltage ...
Elisabetta Coppi   +9 more
wiley   +1 more source

A Study of Rabbit Microsomal Esterases

open access: yes, 1973
1. The microsomal fraction of rabbit liver and kidney preparations (and probably intestinal mucosa) contained a high proportion of the total esterase activity of these organs. All the substrates used confirmed this conclusion. 2.
Turner, John Charles
core   +1 more source

Biochemical biomarkers of Glyphodes pyloalis Walker (Lepidoptera: Pyralidae) in exposure to TiO2 nanoparticles

open access: yesInvertebrate Survival Journal, 2014
Biochemical biomarkers and bioassays, due to their assumed immediate response after acute exposure of the organism to the stressor, are useful tools to gauging anthropogenic impacts. The toxicity of TiO2-nanoparticles (TiO2-NPs) on the Glyphodes pyloalis
N Memarizadeh   +3 more
doaj  

LEAF-CUTTING ANTS Acromyrmex niger SMITH, 1858 (HYMENOPTERA; FORMICIDAE) USED AS BIOINDICATORS OF AGROTOXICS RESIDUES

open access: yesActa Biológica Colombiana, 2014
Despite the condition of leaf-cutting ant pests in agroecosystems, it is undeniable the benefits they can bring in certain situations or environments.
Liriana Belizário Cantagalli   +3 more
doaj   +1 more source

Characterization of Esterases of Tamarindus Indica Seeds [PDF]

open access: yes, 2014
Germinating seeds of Tamarindus indicasynthesizes various enzymes which are required for the degradation of seedreserves such as xyloglucans, fatty acid esters and proteins.
Siddalinga Murthy, K.R., Kantharaju, S.
core   +1 more source

Promiscuous Esterases Counterintuitively Are Less Flexible than Specific Ones

open access: yes, 2022
Understanding mechanisms of promiscuity is increasingly important from a fundamental and application point of view. As to enzyme structural dynamics, more promiscuous enzymes generally have been recognized to also be more flexible.
Nutschel, Christina   +6 more
core   +1 more source

Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor‐Associated Macrophages

open access: yesAdvanced Science, EarlyView.
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley   +1 more source

New Enantioselective Microbial Esterases

open access: yes, 2005
The major goal of our research is the development of synthetically useful selective biotransformations using “new” microbial enzymes by combining natural and non-natural conditions. Enantioselective hydrolysis of chiral or prochiral esters can be used in
F. Molinari
core   +2 more sources

Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States

open access: yesAdvanced Science, EarlyView.
Manipulation of intranuclear divalent cation concentrations rapidly and reversibly remodels chromatin packing domains in living cells. Magnesium depletion disrupts domain compaction, heterochromatin organization, and transcriptional regulation, whereas magnesium loading promotes more compact and stable domains.
Cody L. Dunton   +13 more
wiley   +1 more source

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