Results 51 to 60 of about 53,095 (341)
Engineering an Optogenetic pH‐Modulator in Bacteria
Advanced Science, EarlyView.ABSTRACT Cells in many naturally occurring organisms routinely cooperate to control their extracellular pH in a dynamic and reversible manner, but this capability has been underexplored in synthetic biology. Here, we sought to engineer a microbial system that switches between two states —high and low extracellular pH— with minimal human intervention ...
Jenevieve Kuang +7 more
wiley +1 more source
Angewandte Chemie, EarlyView.This review highlights recent advances in integrating biocatalysis and chemocatalysis in continuous flow to create streamlined, sustainable processes. It examines chemo‐enzymatic cascades combining at least one enzymatic and one chemical step, discusses challenges such as enzyme immobilization, leaching, and reactor clogging, and presents solutions ...
Petros Siasiaridis +2 more
wiley +2 more sources
, 2003 Discussed are the pectin esterases. They comprise enzymes that hydrolyze the esters present in the pectin backbone. Currently three classes of esterases have been identified: the pectin methylesterases, the pectin acetylesterases and the ...
Alebeek, G.J.W.M., van +3 more
core +1 more source
Bioresources and Bioprocessing, 2018 Biological conversion of plant biomass into commercially valuable products is one of the highly studied subjects in the last two decades. Studies were continuously being conducted to understand and develop efficient enzymes for the breakdown and ...
Ayyappa Kumar Sista Kameshwar +1 more
doaj +1 more source
Advanced Science, EarlyView.This study systematically reveals a complex interactive network involving plants, microbes, and insects, elucidating the ecological and molecular mechanisms by which cotton enhances its resistance to aphids through the active recruitment of the beneficial soil bacterium Delftia tsuruhatensis.
Hui Xue +11 more
wiley +1 more source
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Angewandte Chemie, EarlyView.Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley +2 more sources
Insects, 2018 In ongoing screening research for edible plants, Petroselinum crispum essential oil was considered as a potential bioinsecticide with proven antimosquito activity against both the pyrethroid susceptible and resistant strains of Aedes aegypti.
Jitrawadee Intirach +10 more
doaj +1 more source
Hydrolysis of nonpolar n-Alkyl ferulates by feruloyl esterases
, 2016 Ferulic acid is one of the major phenolic acids in plants and can be found esterified to plant cell wall components, but also as long-chain n-alkyl and steryl esters.
Faulds, Craig +9 more
core +1 more source
Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles
Advanced Science, EarlyView.Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu +6 more
wiley +1 more source
Promiscuity‐Guided Enzyme Evolution via Substrate Multiplexed Screening
Angewandte Chemie, EarlyView.Through historical context and recent examples, this Minireview summarizes the strengths, limitations, and practical considerations for the implementation of substrate multiplexed screening (SUMS) in enzyme evolution. ABSTRACT An enzyme's ability to react with diverse substrates while maintaining high yield and selectivity, termed “substrate ...
Holly A. Weilbaker +3 more
wiley +2 more sources