Results 141 to 150 of about 39,453 (284)

Rapid evolution and genetic basis of spinetoram resistance in Phthorimaea absoluta: evidence from six years of monitoring and laboratory selection

open access: yesPest Management Science, EarlyView.
Resistance to spinetoram in Phthorimaea absoluta is rapidly selected and functionally recessive at field‐relevant concentrations. Metabolic detoxification contributes partially, while cross‐resistance to spinosad and increased susceptibility to diamides and isoxazolines highlight practical options for resistance monitoring and insecticide rotation ...
Teófilo P. Langa   +3 more
wiley   +1 more source

Proteo‐transcriptomic insights into the venom composition of the ectoparasitoid Eupelmus urozonus

open access: yesPest Management Science, EarlyView.
Integrated venom‐gland transcriptomics and venom proteomics of Eupelmus urozonus identified 316 venom proteins, including 75 secreted candidates, revealing diverse hydrolases, proteases/inhibitors and many uncharacterized effectors. Abstract BACKGROUND Ectoparasitoid venoms are ‘cocktails’ of bioactive molecules injected during oviposition to paralyze ...
Federica De Stefano   +7 more
wiley   +1 more source

Temporal variation in susceptibility of Euschistus heros (Hemiptera: Pentatomidae) to pyrethroids and neonicotinoids, and spatial patterns of control failure likelihood in southern Brazil

open access: yesPest Management Science, EarlyView.
Monitoring of Euschistus heros populations in Rio Grande do Sul, Brazil, from 2017 to 2026 revealed declining susceptibility to pyrethroids and neonicotinoids. Reduced susceptibility to λ‐cyhalothrin and acetamiprid persisted, whereas declines in susceptibility to bifenthrin, imidacloprid and certain pre‐formulated mixtures emerged more recently ...
Luiz F Warpechowski   +7 more
wiley   +1 more source

Agricultural practices drive multifactorial pyrethroid resistance in Anopheles coluzzii populations from southern Benin. [PDF]

open access: yesTrop Med Health
Boko MP   +15 more
europepmc   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai   +6 more
wiley   +1 more source

A Cytoplasmic pH Sensor Redefines Gating in Bacterial Urea Channels and Acid Resistance

open access: yesSmall, EarlyView.
Bacterial survival in acidic environments requires pH‐gated urea channels. Utilizing complementary approaches, we identify a conserved cytoplasmic glutamic acid residue as a pH sensor in UreI channels. Whereas Gram‐positive bacteria rely solely on this sensor, Gram‐negative bacteria employ a dual‐sensor mechanism with periplasmic residues, revealing a ...
Anna Stoib   +10 more
wiley   +1 more source

Designable Nanozymes for Site‐Selective Amide/Ester Hydrolysis

open access: yesSmall, EarlyView.
Enzymes involved in posttranslational modifications of proteins routinely perform site‐selective catalysis, regardless of the intrinsic reactivities of the myriad of functional groups present. Synthetic mimics of these enzymes are created through molecular imprinting, with catalytic groups positioned precisely near the targeted amide or ester bonds ...
Shashank Singh, Rasmita Barik, Yan Zhao
wiley   +1 more source

Reverse prediction of carbohydrate esterase polysaccharide targets. [PDF]

open access: yesBiotechnol Biofuels Bioprod
Barrett K, Holck J, Meyer AS.
europepmc   +1 more source

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