Results 81 to 90 of about 3,974,478 (339)

Explainable machine learning models for estimating daily dissolved oxygen concentration of the Tualatin River

Engineering Applications of Computational Fluid Mechanics
Monitoring the quality of river water is of fundamental importance and needs to be taken into consideration when it comes to the research into the hydrological field.
Shuguang Li, Sultan Noman Qasem, Shahab S. Band, Rasoul Ameri, Hao-Ting Pai, Saeid Mehdizadeh   +5 more
doaj   +1 more source

Early-stage cost estimation model for power generation project with limited historical data [PDF]

, 2021
Jin Gang Lee, Hyunsoo Lee, Moonseo Park, JoonOh Seo   +3 more
openalex   +1 more source

Hierarchical Estimator

Expert Systems with Applications, 2011
In this paper, a new machine learning solution for function approximation is presented. It combines many simple and relatively inaccurate estimators to achieve high accuracy. It creates - in incremental manner - hierarchical, tree-like structure, adapting it to the specific problem being solved.
Brodowski, Stanisław, Podolak, Igor
openaire   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Estimation of Annual Secondary Lung Cancer Deaths Using Various Adjuvant Breast Radiotherapy Techniques for Early-Stage Cancers [PDF]

, 2021
Jean‐Philippe Pignol, Nienke Hoekstra, Derek Wilke, Hannah Dahn, Maureen Nolan, Frank A. Vicini   +5 more
openalex   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Jointly estimating subnational mortality for multiple populations [PDF]

Demographic Research
BACKGROUND: Understanding patterns in mortality across subpopulations is essential for local health policy decision-making. One of the key challenges of subnational mortality rate estimation is the presence of small populations and zero or near zero ...
Ameer Dharamshi, Monica Alexander, Celeste Winant, Magali Barbieri   +3 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source