Results 51 to 60 of about 441,851 (391)

The Effect of Different Doses of Zearalenone in Feed on the Bioavailability of Zearalenone and Alpha-Zearalenol, and the Concentrations of Estradiol and Testosterone in the Peripheral Blood of Pre-Pubertal Gilts

Toxins, 2020
The objective of this study was to determine the effect of long-term (48 days), per os administration of specific zearalenone (ZEN) doses (20 and 40 μg ZEN/kg BW in experimental groups EI and EII, which were equivalent to 200% and 400% of the upper ...
Łukasz Zielonka, Magdalena Gajęcka, Sylwia Lisieska-Żołnierczyk, Michał Dąbrowski, Maciej T. Gajęcki   +4 more
doaj   +1 more source

Comparison of Short-Term Estrogenicity Tests for Identification of Hormone-Disrupting Chemicals [PDF]

, 1999
The aim of this study was to compare results obtained by eight different short-term assays of estrogenlike actions of chemicals conducted in 10 different laboratories in five countries. Twenty chemicals were selected to represent direct-acting estrogens,
Ana M. Soto, Anette Møller, Anita Oles-Karasko, Anna-Maria Andersson, Bigsby RM, Birgitte Gissel, Bodil Korsgaard, Carlos Sonnenschein, Eva Bonefeld Jørgensen, Farzad Pakdel, Helle Raun Andersen, Henrik Leffers, Herman Autrup, Jesper Bo Nielsen, John McLachlan, John P. Sumpter, Klotz DM, Knud L. Pedersen, Korach KS, Kuiper GGJM, Levin W, Lisette B. Christiansen, Marianne Barfoed, Nicola A. Beresford, Nicolas Olea, Niels Erik Skakkebœk, Philippe Grandjean, Pilar Perez, Poul Bjerregaard, Remy Le Guevel, René Hummel, Soto AM, Soto AM, Steven F. Arnold, Susan M. Thorpe   +34 more
core   +2 more sources

Breast Density and Estradiol Are Major Determinants for Soluble TNF-TNF-R Proteins in vivo in Human Breast Tissue

Frontiers in Immunology, 2022
High mammographic density and exposure to sex steroids are independent risk factors for breast cancer by yet unknown mechanisms. Inflammation is one hallmark of cancer and the tumor necrosis factor family of proteins (TNFSFs) and receptors (TNFRSFs) are ...
Jimmy Ekstrand, Jimmy Ekstrand, Maja Zemmler, Maja Zemmler, Annelie Abrahamsson, Annelie Abrahamsson, Peter Lundberg, Peter Lundberg, Peter Lundberg, Mikael Forsgren, Mikael Forsgren, Mikael Forsgren, Charlotta Dabrosin, Charlotta Dabrosin   +13 more
doaj   +1 more source

Estradiol metabolism in cirrhosis [PDF]

Journal of Clinical Investigation, 1968
Abnormal estrogen metabolism has been found in cirrhosis after administration of intravenous tracers of estradiol-(3)H to 6 patients and 23 healthy controls. The major abnormalities observed involved estrogen metabolites other than the 3 "classic" ones, i.e., estrone (E1), estradiol (E2), and estriol (E3).
Jack Fishman, Leon Hellman, T. F. Gallagher, Barnett Zumoff   +3 more
openaire   +3 more sources

Restoration of serum estradiol and reduced incidence of miscarriage in patients with low serum estradiol during pregnancy: a retrospective cohort study using a multifactorial protocol including DHEA

Frontiers in Reproductive Health
BackgroundLow serum estradiol in early pregnancy is associated with an elevated risk of miscarriage. We sought to determine whether efforts to restore low blood estradiol via estradiol or dehydroepiandrosterone (DHEA) supplementation would reduce the ...
Phil Boyle, Phil Boyle, Karolina Andralojc, Karolina Andralojc, Susanne van der Velden, Shahpar Najmabadi, Theun de Groot, Theun de Groot, Craig Turczynski, Craig Turczynski, Joseph B. Stanford, Joseph B. Stanford   +11 more
doaj   +1 more source

Androgen Regulation of the Mesocorticolimbic System and Executive Function

Frontiers in Endocrinology, 2018
Multiple lines of evidence indicate that androgens, such as testosterone, modulate the mesocorticolimbic system and executive function. This review integrates neuroanatomical, molecular biological, neurochemical, and behavioral studies to highlight how ...
Daniel J. Tobiansky, Daniel J. Tobiansky, Kathryn G. Wallin-Miller, Stan B. Floresco, Stan B. Floresco, Ruth I. Wood, Kiran K. Soma, Kiran K. Soma, Kiran K. Soma   +8 more
doaj   +1 more source

Association of Sex Hormones and Sex Hormone-Binding Globulin Levels With Bone Mineral Density in Adolescents Aged 12–19 Years

Frontiers in Endocrinology, 2022
BackgroundSex hormones are recognized to play a significant role in increasing bone mineral density (BMD) and promoting bone maturation during adolescence.
Ke Xu, Ke Xu, Yicheng Fu, Buzi Cao, Mingyi Zhao   +4 more
doaj   +1 more source

Monitoring of stimulated cycles in assisted reproduction (IVF and ICSI) [PDF]

, 2014
Acknowledgements: We are grateful to Marian Showell for her help in updating the search strategy and carrying out the literature search; to Anne Lethaby for translating the Spanish paper and extracting data; and in particular to Helen Nagels and Jane ...
Bhattacharya, Siladitya, Kang, Angela, Kwan, Irene, Woolner, Andrea   +3 more
core   +3 more sources

Low-dose estradiol and the serotonin-norepinephrine reuptake inhibitor venlafaxine for vasomotor symptoms: a randomized clinical trial.

JAMA Internal Medicine, 2014
IMPORTANCE Estrogen therapy is the gold standard treatment for hot flashes and night sweats, but some women are unable or unwilling to use it because of associated risks.
H. Joffe, K. Guthrie, A. LaCroix, S. Reed, K. Ensrud, J. Manson, K. Newton, E. Freeman, G. Anderson, J. Larson, J. Hunt, J. Shifren, K. Rexrode, B. Caan, B. Sternfeld, J. Carpenter, L. Cohen   +16 more
semanticscholar   +1 more source

Estradiol Inhibits ER Stress-Induced Apoptosis in Chondrocytes and Contributes to a Reduced Osteoarthritic Cartilage Degeneration in Female Mice

Frontiers in Cell and Developmental Biology, 2022
Gender differences are a common finding in osteoarthritis (OA). This may result from a differential response of males and females to endoplasmic reticulum (ER) stress in articular chondrocytes.
Rita Dreier, Thomas Ising, Markus Ramroth, Yvonne Rellmann   +3 more
doaj   +1 more source