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Estrogen, Estrogen Receptor and Lung Cancer [PDF]
Estrogen has been postulated as a contributor for lung cancer development and progression. We reviewed the current knowledge about the expression and prognostic implications of the estrogen receptors (ER) in lung cancer, the effect and signaling pathway of estrogen on lung cancer, the hormone replacement therapy and lung cancer risk and survival, the ...
Li-Han Hsu, Nei-Min Chu, Shu-Huei Kao
openaire +4 more sources
Molecular mechanism of estrogen–estrogen receptor signaling [PDF]
Abstract17β‐Estradiol (E2), as the main circulating estrogen hormone, regulates many tissue and organ functions in physiology. The effects of E2 on cells are mediated by the transcription factors and estrogen receptor (ER)α and ERβ that are encoded by distinct genes.
Yasar, Pelin +4 more
openaire +5 more sources
A Basic Review on Estrogen Receptor Signaling Pathways in Breast Cancer
Breast cancer is the most common cancer and the deadliest among women worldwide. Estrogen signaling is closely associated with hormone-dependent breast cancer (estrogen and progesterone receptor positive), which accounts for two-thirds of tumors. Hormone
Léa Clusan +3 more
semanticscholar +1 more source
Osteoporosis is a serious health issue among aging postmenopausal women. The majority of postmenopausal women with osteoporosis have bone loss related to estrogen deficiency. The rapid bone loss results from an increase in bone turnover with an imbalance
Chui H Cheng, Li-Ru Chen, Kuo-Hu Chen
semanticscholar +1 more source
Rescue of Pressure Overload-Induced Heart Failure by Estrogen Therapy. [PDF]
BackgroundEstrogen pretreatment has been shown to attenuate the development of heart hypertrophy, but it is not known whether estrogen could also rescue heart failure (HF).
Bopassa, Jean C +12 more
core +1 more source
The binding of estrogen and estrogen antagonists to the estrogen receptor
The model of the estrogen receptor as a dimer of identical, interacting subunits and data obtained by Sasson and Notides (1988, Mol. Endocrinol. 2, 307-312) were used to find the standard free energy changes that describe the binding of estradiol and 4-hydroxytamoxifen to the estrogen receptor.
Shlomo Sasson +2 more
openaire +3 more sources
Erythema nodosum as a result of estrogen patch therapy for prostate cancer: a case report. [PDF]
© 2015 Coyle et al.Introduction: Erythema nodosum is often associated with a distressing symptomatology, including painful subcutaneous nodules, polyarthropathy, and significant fatigue.
Abel, P +3 more
core +2 more sources
Effect of soybean supplementation on the memory of alprazolam-induced amnesic mice
Soybean, Glycine max (L.) Merr. (Leguminoseae), is known as golden bean. It contains vegetable protein, oligosaccharide, dietary fiber, vitamins, isoflavones and minerals.
Nitin Bansal, Milind Parle
doaj +1 more source
rLOAD: does sex mediate the effect of acute antiplatelet loading on stroke outcome. [PDF]
BackgroundBiologic sex can influence response to pharmacologic therapy. The purpose of this proof-of-concept study was to evaluate the medicating effects of estrogen in the efficacy of acute antiplatelet loading therapy on stroke outcome in the rabbit ...
Compton, M Peggy +4 more
core +3 more sources
Aromatase Derived Estradiol Within the Thalamus Modulates Pain Induced by Varicella Zoster Virus
Herpes zoster or shingles is the result of varicella zoster virus (VZV) infection and often results in chronic pain that lasts for months after visible symptoms subside. Testosterone often attenuates pain in males.
Phillip R. Kramer +5 more
doaj +1 more source

