Results 1 to 10 of about 2,366,821 (49)
A Basic Review on Estrogen Receptor Signaling Pathways in Breast Cancer
International Journal of Molecular Sciences, 2023 Breast cancer is the most common cancer and the deadliest among women worldwide. Estrogen signaling is closely associated with hormone-dependent breast cancer (estrogen and progesterone receptor positive), which accounts for two-thirds of tumors. Hormone
Léa Clusan +3 more
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Estrogen receptor signaling in the immune system.
Endocrine reviews, 2022 The immune system functions in a sexually dimorphic manner with females exhibiting more robust immune responses than males. However, how female sex hormones affect immune function in normal homeostasis and in autoimmunity is poorly understood.
Binita Chakraborty +5 more
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Estrogen and Progesterone Receptor Testing in Breast Cancer: ASCO/CAP Guideline Update.
Journal of Clinical Oncology, 2020 PURPOSE To update key recommendations of the American Society of Clinical Oncology/College of American Pathologists estrogen (ER) and progesterone receptor (PgR) testing in breast cancer guideline. METHODS A multidisciplinary international Expert Panel
K. Allison +21 more
semanticscholar +1 more source
Interaction of Estrogenic Chemicals and Phytoestrogens with Estrogen Receptor β.
Endocrinology, 1998 The rat, mouse and human estrogen receptor (ER) exists as two subtypes, ERα and ERβ, which differ in the C-terminal ligand-binding domain and in the N-terminal transactivation domain.
G. Kuiper +7 more
semanticscholar +1 more source
Estrogen-Receptor Expression and Function in Female Reproductive Disease
Cells, 2019 Estrogen receptors (ER) include ER alpha, ER beta and new membrane receptor G protein-coupled receptor 30 (GPR30). Estrogen receptors are key receptors to maintain ovarian granulosa cell differentiation, follicle and oocyte growth and development, and ...
Zi-Run Tang +4 more
semanticscholar +1 more source
Mechanisms for estrogen receptor expression in human cancer
Experimental Hematology & Oncology, 2018 Estrogen is a steroid hormone that has critical roles in reproductive development, bone homeostasis, cardiovascular remodeling and brain functions. However, estrogen also promotes mammary, ovarian and endometrial tumorigenesis.
H. Hua +3 more
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International Journal of Molecular Sciences, 2014 It has become increasingly apparent that the pain threshold of females and males varies in an estrogen dependent manner. To investigate the modulation of pain by estrogen and the molecular mechanisms involved in this process.
Guanghui An +3 more
semanticscholar +1 more source
A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling
Science, 2005 The steroid hormone estrogen regulates many functionally unrelated processes in numerous tissues. Although it is traditionally thought to control transcriptional activation through the classical nuclear estrogen receptors, it also initiates many rapid ...
C. Revankar +4 more
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Molecular mechanism of estrogen–estrogen receptor signaling
Reproductive Medicine and Biology, 2016 17β‐Estradiol (E2), as the main circulating estrogen hormone, regulates many tissue and organ functions in physiology. The effects of E2 on cells are mediated by the transcription factors and estrogen receptor (ER)α and ERβ that are encoded by distinct ...
Pelin Yaşar +4 more
semanticscholar +1 more source
The Intestinal Microbiome and Estrogen Receptor-Positive Female Breast Cancer.
Journal of the National Cancer Institute, 2016 The huge communities of residential microbes, including bacteria, viruses, Archaea, and Eukaryotes, that colonize humans are increasingly recognized as playing important roles in health and disease.
M. Kwa +3 more
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