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Estrogen and estrogen receptors in kidney diseases [PDF]

open access: yesRenal Failure, 2021
Acute kidney injury (AKI) and chronic kidney disease (CKD) are posing great threats to global health within this century. Studies have suggested that estrogen and estrogen receptors (ERs) play important roles in many physiological processes in the kidney.
Hao-Yang Ma, Shuang Chen, Yang Du
openaire   +3 more sources

Cyclopia extracts act as selective estrogen receptor subtype downregulators in estrogen receptor positive breast cancer cell lines: Comparison to standard of care breast cancer endocrine therapies and a selective estrogen receptor agonist and antagonist

open access: yesFrontiers in Pharmacology, 2023
Breast cancer is the most diagnosed type of cancer amongst women in economically developing countries and globally. Most breast cancers express estrogen receptor alpha (ERα) and are categorized as positive (ER+) breast cancer. Endocrine therapies such as,
Folasade R. Olayoku   +2 more
doaj   +1 more source

Screening and characterization estrogen receptor ligands from Arnebia euchroma (Royle) Johnst. via affinity ultrafiltration LC-MS and molecular docking

open access: yesFrontiers in Plant Science, 2022
Arnebiae Radix (dried root of Arnebia euchroma (Royle) Johnst.) is a traditional Chinese medicine (TCM) used to treat macular eruptions, measles, sore throat, carbuncles, burns, skin ulcers, and inflammations.
Lian Zhu   +9 more
doaj   +1 more source

Effect of combining CBD with standard breast cancer therapeutics

open access: yesAdvances in Cancer Biology - Metastasis, 2022
Breast cancer is the most common malignancy in women worldwide. Sixty-five percent of breast cancers are estrogen and/or progesterone receptor positive.
Luka Dobovišek   +5 more
doaj   +1 more source

Significance of G Protein-Coupled Estrogen Receptor in the Pathophysiology of Irritable Bowel Syndrome, Inflammatory Bowel Diseases and Colorectal Cancer

open access: yesFrontiers in Endocrinology, 2020
The regulatory role of estrogens and nuclear estrogen receptors, i. e., estrogen receptor α and β has been reported in gastrointestinal diseases. However, the contribution of G protein-coupled estrogen receptor, the membrane-bound estrogen receptor, is ...
Damian Jacenik, Wanda M. Krajewska
doaj   +1 more source

Role of estrogen receptors in cancer: a special emphasis on the therapeutic potential of estrogen receptor β [PDF]

open access: yesPharmaceutical Sciences Asia, 2022
Estrogen receptors are nuclear receptors that play a major role in both physiology and pathology. Estrogen receptor subtypes are currently divided into three groups: estrogen receptor alpha (ERα), estrogen receptor beta (ERβ), and G protein-coupled ...
Emdormi Rymbai   +3 more
doaj   +1 more source

The rate of estrogen receptor‐conversion associated with tumor progression in estrogen receptor‐positive breast cancer patients following adjuvant Tamoxifen administration

open access: yesCancer Reports, 2022
Background Hormone Receptor (HR)‐discordance between primary breast cancer and metastasis is a known biological phenomenon. Discordance studies usually comprise a heterogeneous group of HR‐positive and negative patients and allow for the comparison of ...
Sirus Djahansouzi   +4 more
doaj   +1 more source

PARP7 and Mono-ADP-Ribosylation Negatively Regulate Estrogen Receptor α Signaling in Human Breast Cancer Cells

open access: yesCells, 2021
ADP-ribosylation is a post-translational protein modification catalyzed by a family of proteins known as poly-ADP-ribose polymerases. PARP7 (TIPARP; ARTD14) is a mono-ADP-ribosyltransferase involved in several cellular processes, including responses to ...
Marit Rasmussen   +8 more
doaj   +1 more source

Estrogen, Estrogen Receptor and Lung Cancer [PDF]

open access: yesInternational Journal of Molecular Sciences, 2017
Estrogen has been postulated as a contributor for lung cancer development and progression. We reviewed the current knowledge about the expression and prognostic implications of the estrogen receptors (ER) in lung cancer, the effect and signaling pathway of estrogen on lung cancer, the hormone replacement therapy and lung cancer risk and survival, the ...
Li-Han Hsu, Nei-Min Chu, Shu-Huei Kao
openaire   +2 more sources

Estrogen-Independent Activation of Estrogen Receptors [PDF]

open access: yesHypertension, 2011
See related article, pp 1161–1166 Sex differences showing a lower prevalence and better outcome after ischemic stroke in women have been described, differences that are abrogated by natural or surgical menopause.1,2 High levels of endogenous estrogens in premenopausal women have been associated with reduced risk for a number of diseases, such as ...
Matthias, Barton   +2 more
openaire   +2 more sources

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