KMT2C mediates the estrogen dependence of breast cancer through regulation of ERα enhancer function [PDF]
, 2018 Estrogen receptor alpha (ER alpha) is a ligand-activated nuclear receptor that directs proliferation and differentiation in selected cancer cell types including mammary-derived carcinomas.
Abdel-Wahab, Omar +13 more
core +2 more sources
Immunoekspresi Reseptor α pada Poket Periodontal Lebih Banyak daripada Reseptor Estrogen β
Journal of Dentistry Indonesia, 2013 Studies have been reported on the association between menopause and periodontal disease related to estrogen deficiency. Although the estrogen receptor has been demonstrated on some oral tissues, the presence of estrogen receptors on periodontal pockets ...
Yuliana Mahdiyah Da’at Arina
doaj +1 more source
Frontiers in Endocrinology, 2023 While estrogens are well known for their pivotal role in the female reproductive system, they also play a crucial function in regulating physiological processes associated with learning and memory in the brain. Moreover, they have neuroprotective effects
Kaoru Sato +3 more
doaj +1 more source
Exposure to Endocrine Disruptors and Nuclear Receptors Gene Expression in Infertile and Fertile Men from Italian Areas with Different Environmental Features [PDF]
, 2015 Internal levels of selected endocrine disruptors (EDs) (i.e., perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), di-2-ethylhexyl-phthalate (DEHP), mono-(2-ethylhexyl)-phthalate (MEHP), and bisphenol A (BPA)) were analyzed in blood/serum of ...
Bergamasco B +14 more
core +2 more sources
Journal of Traditional and Complementary Medicine, 2018 The purpose of this study was to investigate the effect of genistein administration on the modulation of the estrogen receptor, inhibition of inflammation and angiogenesis in the murine model of peritoneal endometriosis.
Sutrisno Sutrisno +9 more
doaj +1 more source
Advances in breast cancer treatment and prevention: preclinical studies on aromatase inhibitors and new selective estrogen receptor modulators (SERMs). [PDF]
, 2003 Intensive basic and clinical research over the past 20 years has yielded crucial molecular understanding into how estrogen and the estrogen receptor act to regulate breast cancer and has led to the development of more effective, less toxic, and safer ...
Brown, Powel H +2 more
core +2 more sources
Molecular Mechanisms of Endocrine Resistance in Estrogen-Receptor-Positive Breast Cancer
Frontiers in Endocrinology, 2021 The estrogen receptor is a vital receptor for therapeutic targets in estrogen receptor-positive breast cancer. The main strategy for the treatment of estrogen receptor-positive breast cancers is blocking the estrogen action on estrogen receptors by ...
Esmael Besufikad Belachew +2 more
doaj +1 more source
Effect of cyclosporine on hepatic cytosolic estrogen and androgen receptor levels before and after partial hepatectomy [PDF]
, 1990 Estrogen and androgen receptors within the liver have been reported to modulate the hepatic regenerative response to partial hepatectomy. Moreover, cyclosporine has several untoward effects that might occur as a consequence of alterations in sex hormone ...
A Francavilla +33 more
core +1 more source
Archives of Pathology & Laboratory Medicine, 2011 Abstract Context—A new class of estrogen receptors was discovered in 1996 and named estrogen receptor β (ER-B); the traditional estrogen receptor, which until a little more than 10 years ago was thought of as the only estrogen receptor in existence, is now called estrogen receptor α. Estrogen receptor β has at least 5 isoforms, which may
Mamoun, Younes, Naoko, Honma
openaire +2 more sources
Activation of an Estrogen/ Estrogen Receptor Signaling by BIG3 Through Its Inhibitory Effect on Nuclear Transport of PHB2/REA in Breast Cancer [PDF]
, 2009 Breast cancer is known to be a hormone-dependent disease, and estrogens through an interaction with estrogen receptor (ER) enhance the proliferative and metastatic activity of breast tumor cells.
Arata Shimo +10 more
core +2 more sources