Results 191 to 200 of about 2,198,676 (277)

Comprehensive Characterization of Acer truncatum Leaf Extract: Identification of Systemic Metabolites and Effects on Performance, Antioxidant Status, and Intestinal Microbiota in Laying Hens

Animal Research and One Health, EarlyView.
Dietary A. truncatum leaf extract is absorbed and improves laying performance in aged hens by enhancing systemic antioxidant capacity and modulating the gut microbiota. ABSTRACT The demand for natural feed additives is considerably increasing in the antibiotic‐free feed era.
Kailong Qin, Jiantao Yang, Minglu Gao, Xiaozhao Tao, Xin Yang, Yanli Liu, Xiaojun Yang   +6 more
wiley   +1 more source

Investigation of variants in estrogen receptor genes and perinatal depression

, 2018
Ene-Choo Tan,1,2 Hwee-Woon Lim,1 Tze-Ern Chua,2,3 Hui-San Tan,1 Theresa MY Lee,2,3 Helen Y Chen2,3 1KK Research Centre, KK Women’s and Children’s Hospital, Singapore, Singapore; 2Paediatrics Academic Clinical Programme, SingHealth Duke-NUS ...
Lim HW, Chua TE, Chen HY, Tan HS, Tan EC, Lee TMY   +5 more
core  

ERβ-Score: An Interpretable Machine Learning-Based Scoring Function and Web Server for Estrogen Receptor β-Guided Drug Discovery in Triple-Negative Breast Cancer. [PDF]

Int J Mol Sci
Khan A, Zahid MA, Kouidri W, Mohamed OA, Gharaibeh AM, Mohamed LI, Al-Mansori AA, Elsayed MH, Mohammad A, Al-Jabiry A, Shkoor M, Al-Zoubi RM, Agouni A.   +12 more
europepmc   +1 more source

Estrogen Receptor β Expression and Its Clinical Implication in Breast Cancers: Favorable or Unfavorable? [PDF]

J Breast Cancer, 2022
Choi Y.
europepmc   +1 more source

Immune Complexes Shape the Pathogenicity of Autoantibodies in Systemic Autoimmune Diseases: Insights From an FcγRIIIA‐Reporter Assay

Arthritis &Rheumatology, EarlyView.
Objective Immune complexes (ICs), formed by autoantigen and autoantibody, play a pathogenic role in systemic autoimmune diseases through stimulation of Fcγ receptors (FcγR). However, studies investigating bioactivity of circulating ICs across various diseases remain limited.
Koji Suzuki, Masaru Takeshita, Yuki Imai, Hiroyuki Fukui, Kazunori Furuhashi, Kotaro Matsumoto, Jun Kikuchi, Keiko Yoshimoto, Yuko Kaneko   +8 more
wiley   +1 more source

Extracellular Acidosis Differentially Regulates Estrogen Receptor β-Dependent EMT Reprogramming in Female and Male Melanoma Cells. [PDF]

Int J Mol Sci, 2022
Peppicelli S, Ruzzolini J, Lulli M, Biagioni A, Bianchini F, Caldarella A, Nediani C, Andreucci E, Calorini L.   +8 more
europepmc   +1 more source

The Nuclear Receptor Testicular Receptor 4 Orchestrates Cytoskeletal Organization in a G Protein Subunit Alpha 12/Rho‐Associated Protein Kinase–Dependent Manner to Promote Myofibroblast Differentiation and Tissue Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang, Lichong Shen, Junhui Zheng, Gisela Baur, Dilidaer Yasen, Honglin Zhu, Yi‐Nan Li, Xianyi Meng, Thuong Trinh‐Minh, Tim Filla, Debomita Chakraborty, Andrea‐Hermina Györfi, Christina Bergmann, Adam Reich, Alexander Kreuter, Georg Schett, Jörg H. W. Distler   +16 more
wiley   +1 more source

Estrogen receptor β target gene expression reveals novel repressive functions in aggressive breast cancer. [PDF]

NPJ Breast Cancer
Tastsoglou S, Karagounis IV, Miliotis M, Nagandla H, Zambo KDA, Liousia M, Ueno N, Maity A, Hatzigeorgiou AG, Thomas C.   +9 more
europepmc   +1 more source

Estrogen Acts Through Estrogen Receptor-β to Promote Mannan-Induced Psoriasis-Like Skin Inflammation. [PDF]

Front Immunol, 2022
Wu H, Zeng L, Ou J, Wang T, Chen Y, Nandakumar KS.   +5 more
europepmc   +1 more source

CD248/Endosialin regulates synovial fibroblast state to control coupling of inflammation and bone damage in murine models of immune‐mediated inflammatory arthritis and ageing

Arthritis &Rheumatology, Accepted Article.
Objective Synovial fibroblasts directly contribute to inflammation and damage in immune‐mediated inflammatory arthritis. CD248/Endosialin is expressed by fibroblasts in the synovium, is highly upregulated during inflammation and has been proposed as a potential therapeutic target.
Samuel Kemble, Corinna Wehmeyer, James M. Brown, Charlotte G. Smith, Holly R. Adams, Eva Crombie, Ellie Northall, Maryam Imran, Paulynn Chin, Harris R. Perlman, Christopher D. Buckley, Adam P. Croft, Amy J. Naylor   +12 more
wiley   +1 more source