Results 1 to 10 of about 288,777 (270)

17β-estradiol mediates sex-biased progesterone receptor expression via estrogen receptor α in chicken pituitary [PDF]

Poultry Science
Sex-biased in gene expression is a pervasive biological phenomenon in animals and plays critical roles in sex-dependent physiological activities. While previous studies have identified numerous genes displaying sex-biased expression at pre- or post ...
Guixian Bu, Shasha Guo, Li Guo, Yaling Wang, Jingyi Lin, Xinchun Li, Lingyang Li, Linyan Huang, Xianyin Zeng, Jing Feng, Caiyun Sun, Fengyan Meng   +11 more
doaj   +2 more sources

Estrogen deprivation and estrogen receptor α antagonism decrease DSS colitis in female mice [PDF]

Pharmacology Research & Perspectives
The association of hormonal contraception with increased risk of inflammatory bowel disease (IBD) observed in females suggests involvement of ovarian hormones, such as estradiol, and the estrogen receptors in the progression of intestinal inflammation ...
Anja Hjelt, Santeri Anttila, Anu Wiklund, Anne Rokka, Darin Al‐Ramahi, Diana M. Toivola, Lauri Polari, Jorma Määttä   +7 more
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Progranulin deficiency associates with postmenopausal osteoporosis via increasing ubiquitination of estrogen receptor α [PDF]

Genes and Diseases
Estrogen deficiency is considered the most important cause of postmenopausal osteoporosis. However, the underlying mechanism is still not completely understood.
Guangfei Li, Aifei Wang, Wei Tang, Wenyu Fu, Qingyun Tian, Jinlong Jian, Michal Lata, Aubryanna Hettinghouse, Yuanjing Ding, Jianlu Wei, Xiangli Zhao, Mingyong Wang, Qirong Dong, Chuanju Liu, Youjia Xu   +14 more
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Expression of estrogen receptors alpha (ERs α) and folliculogenesis profile in ovary of the rats ovarian hypofunction model [PDF]

Jurnal Ilmu-Ilmu Peternakan, 2021
Ovarian hypofunction is one of the reproductive disorders that occur due to a decrease in ovarian function that causes animals to not experience heat. The purpose of this study was to determine the effect of GnRH antagonist hormone interventions on ovarian hypofunction model rats by looking at the expression of alpha ERs (ERs α) and the profile of ...
Aulia Firmawati, Mitra Artha Kurnia Hutabarat, Herlina Pratiwi, Alibiruni Haryo   +3 more
openaire   +2 more sources

PARP7 and Mono-ADP-Ribosylation Negatively Regulate Estrogen Receptor α Signaling in Human Breast Cancer Cells

Cells, 2021
ADP-ribosylation is a post-translational protein modification catalyzed by a family of proteins known as poly-ADP-ribose polymerases. PARP7 (TIPARP; ARTD14) is a mono-ADP-ribosyltransferase involved in several cellular processes, including responses to ...
Marit Rasmussen, Susanna Tan, Venkata S. Somisetty, David Hutin, Ninni Elise Olafsen, Anders Moen, Jan H. Anonsen, Denis M. Grant, Jason Matthews   +8 more
doaj   +1 more source

The effect of Vigna unguiculata on the estrogen receptor-α expression and the endometrial thickness in rats treated with depot medroxyprogesterone acetate (DMPA)

Healthcare in Low-resource Settings, 2023
Depot medroxyprogesterone acetate (DMPA) is a contraceptive method that prevents ovulation and reduces endometrial thickness. This study aimed to investigate the influence of Vigna unguiculata (VU) on estrogen receptor-α expression and endometrial ...
Rizki Fitrianingtyas, Indah Christiana, Ririn Handayani, Ernawati Anggraeni, Zaida Mauludiyah, Sholihatil Hidayati   +5 more
doaj   +1 more source

Tie2-Cre–Induced Inactivation of Non-Nuclear Estrogen Receptor-α Signaling Abrogates Estrogen Protection Against Vascular Injury

JACC: Basic to Translational Science, 2023
Summary: Using the Cre-loxP system, we generated the first mouse model in which estrogen receptor-α non-nuclear signaling was inactivated in endothelial cells. Estrogen protection against mechanical vascular injury was impaired in this model. This result
Pang-Yen Liu, MD, PhD, Nobuaki Fukuma, MD, PhD, Yukio Hiroi, MD, PhD, Akiko Kunita, PhD, Hiroyuki Tokiwa, MD, PhD, Kazutaka Ueda, MD, PhD, Taro Kariya, MD, PhD, Genri Numata, MD, PhD, Yusuke Adachi, MD, PhD, Miyu Tajima, MD, PhD, Masayuki Toyoda, MD, PhD, Yuxin Li, MD, PhD, Kensuke Noma, MD, PhD, Mutsuo Harada, MD, PhD, Haruhiro Toko, MD, PhD, Tetsuo Ushiku, MD, PhD, Yoshimitsu Kanai, MD, PhD, Eiki Takimoto, MD, PhD, James K. Liao, MD, Issei Komuro, MD, PhD   +19 more
doaj   +1 more source

Screening and characterization estrogen receptor ligands from Arnebia euchroma (Royle) Johnst. via affinity ultrafiltration LC-MS and molecular docking

Frontiers in Plant Science, 2022
Arnebiae Radix (dried root of Arnebia euchroma (Royle) Johnst.) is a traditional Chinese medicine (TCM) used to treat macular eruptions, measles, sore throat, carbuncles, burns, skin ulcers, and inflammations.
Lian Zhu, Lian Zhu, Sheng-jun Ma, Ming-juan Liu, Kai-lin Li, Shuai E, Zi-ming Wang, Sha-ni Li, Sheng-lan Zhang, Wei Cai   +9 more
doaj   +1 more source

Estrogen Biosynthesis and Signal Transduction in Ovarian Disease

Frontiers in Endocrinology, 2022
Estrogen mainly binds to estrogen receptors (ERs) to regulate menstrual cycles and reproduction. The expression of ERalpha (ERα), ERbeta (ERβ), and G-protein-coupled estrogen receptor (GPER) mRNA could be detected in ovary, suggesting that they play an ...
Xue-Ling Xu, Zheng-Yuan Huang, Kun Yu, Jun Li, Xiang-Wei Fu, Shou-Long Deng   +5 more
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Mitochondria-targeted triphenylphosphonium-based compounds do not affect estrogen receptor α [PDF]

PeerJ, 2020
Background Targeting negatively charged mitochondria is often achieved using triphenylphosphonium (TPP) cations. These cationic vehicles may possess biological activity, and a docking study indicates that TPP-moieties may act as modulators of signaling ...
Ludmila A. Zinovkina, Alina K. Galivondzhyan, Anastasia S. Prikhodko, Ivan I. Galkin, Roman A. Zinovkin   +4 more
doaj   +2 more sources