Results 21 to 30 of about 97,723 (266)

Genistein modulates the estrogen receptor and suppresses angiogenesis and inflammation in the murine model of peritoneal endometriosis

Journal of Traditional and Complementary Medicine, 2018
The purpose of this study was to investigate the effect of genistein administration on the modulation of the estrogen receptor, inhibition of inflammation and angiogenesis in the murine model of peritoneal endometriosis.
Sutrisno Sutrisno, Hardianti Aprina, Happy Marthalena Simanungkalit, Asti Andriyani, Wisnu Barlianto, Hidayat Sujuti, Sanarto Santoso, Pande Made Dwijayasa, Endang Sri Wahyuni, Edy Mustofa   +9 more
doaj   +1 more source

Characterization of an Estrogen Receptor α-Selective ¹⁸ F-Estradiol PET Tracer. [PDF]

World J Nucl Med
Objective: Conventional imaging of cancer with modalities such as computed tomography or magnetic resonance imaging provides little information about the underlying biology of the cancer and consequently little guidance for systemic treatment choices ...
Sluka P, Ackermann U, Rigopoulos A, Wardan H, Pezaro C, Burvenich IJG, Scott AM, Davis ID.   +7 more
europepmc   +2 more sources

Estrogen receptor beta and G protein-coupled estrogen receptor 1 are involved in the acute estrogenic regulation of arginine-vasopressin immunoreactive levels in the supraoptic and paraventricular hypothalamic nuclei of female rats [PDF]

, 2019
The ovarian hormone 17β-estradiol is known to regulate the release, expression and immunoreactivity of arginine-vasopressin (AVP) in the supraoptic and paraventricular hypothalamic nuclei of rodents.
Collado, Paloma, Panzica, Giancarlo, Marraudino, Marilena, Amorim, Miguel de, Pinos, Helena, Lagunas García, Luisa Natalia, García Segura, L. M., Grassi, Daniela, Garcia-Segura, Luis   +8 more
core   +1 more source

Xenoestrogens alter estrogen receptor (ER) α intracellular levels.

PLoS ONE, 2014
17β-estradiol (E2)-dependent estrogen receptor (ER) α intracellular concentration is a well recognized critical step in the pleiotropic effects elicited by E2 in several target tissues.
Piergiorgio La Rosa, Marco Pellegrini, Pierangela Totta, Filippo Acconcia, Maria Marino   +4 more
doaj   +1 more source

Epigenetic changes in the estrogen receptor α gene promoter: implications in sociosexual behaviors [PDF]

Frontiers in Neuroscience, 2014
Estrogen action through estrogen receptor α (ERα) is involved in the control of sexual and social behaviors in adult mammals. Alteration of ERα gene activity mediated by epigenetic mechanisms, such as histone modifications and DNA methylation, in particular brain areas appears to be crucial for determining the extents of these behaviors between the ...
openaire   +3 more sources

Estrogen: An Emerging Regulator of Insulin Action and Mitochondrial Function

Journal of Diabetes Research, 2015
Clinical trials and animal studies have revealed that loss of circulating estrogen induces rapid changes in whole body metabolism, fat distribution, and insulin action.
Anisha A. Gupte, Henry J. Pownall, Dale J. Hamilton   +2 more
doaj   +1 more source

Expression patterns of STAT3, ERK and estrogen-receptor α are associated with development and histologic severity of hepatic steatosis: a retrospective study

Diagnostic Pathology, 2018
Background Hepatic steatosis renders hepatocytes vulnerable to injury, resulting in the progression of preexisting liver disease. Previous animal and cell culture studies implicated mammalian target of rapamycin (mTOR), signal transducer and activator of
Euno Choi, Won Kim, Sae Kyung Joo, Sunyoung Park, Jeong Hwan Park, Yun Kyung Kang, So-Young Jin, Mee Soo Chang   +7 more
doaj   +1 more source

Predominant Role of Nuclear Versus Membrane Estrogen Receptor α in Arterial Protection: Implications for Estrogen Receptor α Modulation in Cardiovascular Prevention/Safety

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Although estrogen receptor α (ERα) acts primarily as a transcription factor, it can also elicit membrane‐initiated steroid signaling. Pharmacological tools and transgenic mouse models previously highlighted the key role of ERα membrane ...
Emmanuel Guivarc'h, Mélissa Buscato, Anne‐Laure Guihot, Julie Favre, Emilie Vessières, Linda Grimaud, Jamal Wakim, Nada‐Joe Melhem, Rana Zahreddine, Marine Adlanmerini, Laurent Loufrani, Claude Knauf, John A. Katzenellenbogen, Benita S. Katzenellenbogen, Jean‐Michel Foidart, Pierre Gourdy, Françoise Lenfant, Jean‐François Arnal, Daniel Henrion, Coralie Fontaine   +19 more
doaj   +1 more source

Estrogen-related receptor α (ERRα) : a novel target in type 2 diabetes [PDF]

, 2005
Recent studies have shown that reduced mitochondrial content and function in skeletal muscle are common features of type 2 diabetes. Here, we review the molecular mechanisms involved in the regulation of mitochondrial genes in skeletal muscle, focusing ...
Handschin, C., Mootha, V. K.
core   +1 more source

Estrogen receptor β exhibited anti-tumor effects on osteosarcoma cells by regulating integrin, IAP, NF-kB/BCL-2 and PI3K/Akt signal pathway

Journal of Bone Oncology, 2017
This study aimed to investigate the effects of Estrogen receptor β (ERβ) on osteosarcoma cells, and explore the regulatory mechanisms involved in this process. Osteosarcoma U2-OS cells consisted four groups, and treated by E2, E2 + LY294002 (ERβ agonists), E2 + ERβ siRNA, E2 + ERβ siRNA + LY294002, respectively.
Minfei Yang, Bing Liu, Libin Jin, Huimin Tao, Zhengming Yang   +4 more
openaire   +3 more sources