Mitochondria-targeted triphenylphosphonium-based compounds do not affect estrogen receptor α [PDF]
PeerJ, 2020 Background Targeting negatively charged mitochondria is often achieved using triphenylphosphonium (TPP) cations. These cationic vehicles may possess biological activity, and a docking study indicates that TPP-moieties may act as modulators of signaling ...
Ludmila A. Zinovkina +4 more
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Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes. [PDF]
, 2012 BACKGROUND The intricate interactions between the immune, endocrine and central nervous systems shape the innate immune response of the brain. We have previously shown that estradiol suppresses expression of immune genes in the frontal cortex of ...
Nicole Berchtold +15 more
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The Effect of Sambiloto Extract on the Expression of β Estrogen Receptors in Ovaries and Lust Cycle in Mice Model PCOS - Insulin Resistance [PDF]
Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery), 2021 Infertility was a serious problem in the reproductive period, one of the caused of infertility were common in women of childbearing age group is Polycystic Ovary Syndrome (PCOS).Sambiloto (Andrographis paniculata Nees), had been already known contain flavonoid and lactones.
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Reporter cell lines to evaluate the selectivity of chemicals for human and zebrafish estrogen and peroxysome proliferator activated γ receptors [PDF]
Frontiers in Neuroscience, 2015 Zebrafish is increasingly used as an animal model to study the effects of environmental nuclear receptors (NRs) ligands. As most of these compounds have only been tested on human NRs, it is necessary to measure their effects on zebrafish NRs. Estrogen receptors (ER) α and β and peroxysome proliferator activated receptor (PPAR) γ are main targets of ...
Grimaldi, Marina +5 more
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The endometrial expression level of estrogen-α and VEGF-A in female rats administered with a low dose of estrogen in early clomiphene citrate therapy [PDF]
Iraqi Journal of Veterinary Sciences, 2023 The study was conducted to determine the effect of low-dose estrogen in the early cycle of clomiphene citrate therapy on the expression of level estrogen receptor α (ERα) and VEGF-A in the endometrium.
Rahmat L. Landahur +3 more
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Journal of Traditional and Complementary Medicine, 2018 The purpose of this study was to investigate the effect of genistein administration on the modulation of the estrogen receptor, inhibition of inflammation and angiogenesis in the murine model of peritoneal endometriosis.
Sutrisno Sutrisno +9 more
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Insights from the Structure of Estrogen Receptor into the Evolution of Estrogens: Implications for Endocrine Disruption [PDF]
, 2011 In the last decade, there has been important progress in understanding the origins and evolution of receptors for adrenal steroids (aldosterone, cortisol) and sex steroids (estradiol, progesterone, testosterone) due to the sequencing of genomes from ...
Michael E. Baker
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Immunoekspresi Reseptor α pada Poket Periodontal Lebih Banyak daripada Reseptor Estrogen β
Journal of Dentistry Indonesia, 2013 Studies have been reported on the association between menopause and periodontal disease related to estrogen deficiency. Although the estrogen receptor has been demonstrated on some oral tissues, the presence of estrogen receptors on periodontal pockets ...
Yuliana Mahdiyah Da’at Arina
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Xenoestrogens alter estrogen receptor (ER) α intracellular levels.
PLoS ONE, 2014 17β-estradiol (E2)-dependent estrogen receptor (ER) α intracellular concentration is a well recognized critical step in the pleiotropic effects elicited by E2 in several target tissues.
Piergiorgio La Rosa +4 more
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Estrogen: An Emerging Regulator of Insulin Action and Mitochondrial Function
Journal of Diabetes Research, 2015 Clinical trials and animal studies have revealed that loss of circulating estrogen induces rapid changes in whole body metabolism, fat distribution, and insulin action.
Anisha A. Gupte +2 more
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