Differential ligand binding affinities of human estrogen receptor-α isoforms. [PDF]
PLoS ONE, 2013 Rapid non-genomic effects of 17β-estradiol are elicited by the activation of different estrogen receptor-α isoforms. Presence of surface binding sites for estrogen have been identified in cells transfected with full-length estrogen receptor-α66 (ER66 ...
Amanda H Y Lin +6 more
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Expression of Estrogen Receptor α by Decidual Macrophages in Preeclampsia
Biomedicines, 2021 Preeclampsia is a gestation-associated hypertensive syndrome that threatens the life and health of the mother and the child. The condition is presumably caused by systemic failure with a strong involvement of innate immunity.
Polina Vishnyakova +11 more
doaj +3 more sources
Receptor for activated C kinase 1 protein binds to and activates the human estrogen receptor α [PDF]
Journal of Medical Sciences, 2014 The classical concept of estrogen receptor (ER) activation is that steroid passes the cell membrane, binds to its specific protein receptor in the cell′s cytoplasm and the steroid-receptor complex travels to the nucleus where it activates responsive ...
Eric Adams +3 more
doaj +2 more sources
Acta Medica Indonesiana, 2014 Estrogen has an important role in regulation of fat metabolism. Recent studies indicated that this process occurred due to inhibition of lipolysis by external estrogen administration.
Harry F Luglio
doaj +6 more sources
Mitochondria-targeted triphenylphosphonium-based compounds do not affect estrogen receptor α [PDF]
PeerJ, 2020 Background Targeting negatively charged mitochondria is often achieved using triphenylphosphonium (TPP) cations. These cationic vehicles may possess biological activity, and a docking study indicates that TPP-moieties may act as modulators of signaling ...
Ludmila A. Zinovkina +4 more
doaj +2 more sources
The Effect of Sambiloto Extract on the Expression of β Estrogen Receptors in Ovaries and Lust Cycle in Mice Model PCOS - Insulin Resistance [PDF]
Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery), 2021 Infertility was a serious problem in the reproductive period, one of the caused of infertility were common in women of childbearing age group is Polycystic Ovary Syndrome (PCOS).Sambiloto (Andrographis paniculata Nees), had been already known contain flavonoid and lactones.
openaire +1 more source
Reporter cell lines to evaluate the selectivity of chemicals for human and zebrafish estrogen and peroxysome proliferator activated γ receptors [PDF]
Frontiers in Neuroscience, 2015 Zebrafish is increasingly used as an animal model to study the effects of environmental nuclear receptors (NRs) ligands. As most of these compounds have only been tested on human NRs, it is necessary to measure their effects on zebrafish NRs. Estrogen receptors (ER) α and β and peroxysome proliferator activated receptor (PPAR) γ are main targets of ...
Grimaldi, Marina +5 more
openaire +4 more sources
Immunoekspresi Reseptor α pada Poket Periodontal Lebih Banyak daripada Reseptor Estrogen β
Journal of Dentistry Indonesia, 2013 Studies have been reported on the association between menopause and periodontal disease related to estrogen deficiency. Although the estrogen receptor has been demonstrated on some oral tissues, the presence of estrogen receptors on periodontal pockets ...
Yuliana Mahdiyah Da’at Arina
doaj +1 more source
The endometrial expression level of estrogen-α and VEGF-A in female rats administered with a low dose of estrogen in early clomiphene citrate therapy [PDF]
Iraqi Journal of Veterinary Sciences, 2023 The study was conducted to determine the effect of low-dose estrogen in the early cycle of clomiphene citrate therapy on the expression of level estrogen receptor α (ERα) and VEGF-A in the endometrium.
Rahmat L. Landahur +3 more
doaj +1 more source
Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes. [PDF]
, 2012 BACKGROUND The intricate interactions between the immune, endocrine and central nervous systems shape the innate immune response of the brain. We have previously shown that estradiol suppresses expression of immune genes in the frontal cortex of ...
Nicole Berchtold +15 more
core +1 more source