Results 101 to 110 of about 121,912 (288)

Exploiting synthetic lethal vulnerabilities for cancer therapy [PDF]

arXiv, 2016
Synthetic lethality refers to a combination of two or more genetic events (typically affecting different genes) in which the co-occurrence of the events results in cell or organismal lethality, but the cell or organism remains viable when only one of the events occurs.
arxiv  

Increased vascular catecholamine sensitivity and alpha-adrenergic receptor affinity in female and estrogen-treated male rats. [PDF]

, 1982
Wilson S. Colucci, Michael A. Gimbrone, Margaret K. McLaughlin, W Halpern, R. Wayne Alexander   +4 more
openalex   +1 more source

Sugar‐sensing swodkoreceptors and swodkocrine signaling

Animal Models and Experimental Medicine, EarlyView.
Sugar‐sensing swodkoreceptors that trigger swodkocrine signaling. Abstract Sugars are one of the major metabolites and are essential for nucleic acid synthesis and energy production. In addition, sugars can act as signaling molecules. To study sugar signaling at the systemic level, there is an urgent need to systematically identify sugar‐sensing ...
Savani Anbalagan
wiley   +1 more source

Regulation of myocardial and vascular alpha-adrenergic receptor affinity. Effects of guanine nucleotides, cations, estrogen, and catecholamine depletion. [PDF]

, 1984
Wilson S. Colucci, Michael A. Gimbrone, R. Wayne Alexander   +2 more
openalex   +1 more source

Induction of Cell Death by Combined Treatment with Photosensitizer‐Chitosan Nanoparticles and the Ferroptosis Inducer RSL3 in Breast Cancer Cell Lines

Advanced NanoBiomed Research, EarlyView.
This study demonstrates that combination of phosphosensitizer‐conjugated chitosan nanoparticles and ferroptosis inducer RSL3 increases cell death in mesenchymal breast cancer cells. Data suggests that this is attributed to variations in ferroptosis‐related protein expression, lipid peroxydation and mitochondrial function.
Marek Feith, Saikat Das Sajib, Anne Grethe Myrann, Anders Høgset, Pablo Garrido, Alfredo Martinez, Erik Knutsen, Kirsten Sandvig, Tore Skotland, Gunhild Mari Mælandsmo, Tore‐Geir Iversen   +10 more
wiley   +1 more source

Genes Associated with the Immune System Affected by Ionizing Radiation and Estrogen in an Experimental Breast Cancer Model

Biology
Breast cancer is a global health issue that, when in the metastasis stage, is characterized by the lack of estrogen receptor-α, the progesterone receptor, and human epidermal growth receptor expressions.
Gloria M. Calaf, Debasish Roy, Lilian Jara, Carmen Romero, Leodan A. Crispin   +4 more
doaj   +1 more source

Detection of estrogen receptor alpha, carbonic anhydrase II and tartrate-resistant acid phosphatase mRNAs in putative mononuclear osteoclast precursor cells of neonatal rats by fluorescence in situ hybridization [PDF]

, 1998
WH Huang, AT Lau, LL Daniels, Hiroshi Fujii, Ulrich Seydel, DJ Wood, JM Papadimitriou, Minghao Zheng   +7 more
openalex   +1 more source

Positron emission tomography: Evolving modalities, radiopharmaceuticals and professional collaboration

Journal of Medical Radiation Sciences, Volume 69, Issue 4, Page 415-418, December 2022., 2022
PET has experienced exponential growth over the last few decades in terms of innovative technologies and novel radiopharmaceuticals. This has fostered increasing collaboration between radiographers and nuclear medicine technologists. Abstract Positron emission tomography (PET) as an imaging modality has undergone considerable innovation over the past ...
Sally L. Ayesa, Andrew Murphy
wiley   +1 more source

Expression profile and prognostic role of sex hormone receptors in gastric cancer

BMC Cancer, 2012
Background Increasing interest has been devoted to the expression and possible role of sex hormone receptors in gastric cancer, but most of these findings are controversial. In the present study, the expression profile of sex hormone receptors in gastric
Gan Lu, He Jian, Zhang Xia, Zhang Yong-Jie, Yu Guan-Zhen, Chen Ying, Pan Jun, Wang Jie-Jun, Wang Xi   +8 more
doaj   +1 more source

Estrogen Receptor Alpha (ER-α) and Beta (ER-β) mRNAs in Normal Ovary, Ovarian Serous Cystadenocarcinoma and Ovarian Cancer Cell Lines: Down-Regulation of ER-β in Neoplastic Tissues [PDF]

, 1998
A. W. Brandenberger, Meng Kian Tee, Roberts B. Jaffe   +2 more
openalex   +1 more source