Results 11 to 20 of about 121,912 (288)
In Silico Evaluation of Alpha Mangostin and its Derivatives as a potential Anti-Cancer Agents [PDF]
BIO Web of ConferencesAlpha-Mangostin, a natural xanthone from Garcinia mangostana, and its structurally optimized derivatives were evaluated as anticancer agents targeting estrogen receptor proteins linked to breast cancer: Estrogen Receptor Alpha(3ERT), Estrogen Receptor ...
V Harini Rakshitha +3 more
doaj +1 more source
Estrogen/estrogen receptor alpha signaling in mouse posterofrontal cranial suture fusion. [PDF]
PLoS ONE, 2009 While premature suture fusion, or craniosynostosis, is a relatively common condition, the cause is often unknown. Estrogens are associated with growth plate fusion of endochondral bones.
Aaron W James +8 more
doaj +1 more source
Estrogen alpha receptor antagonists for the treatment of breast cancer: a review
Chemistry Central Journal, 2018 Background Cancer is at present one of the leading causes of death in the world. It accounts for 13% of deaths occurred worldwide and is continuously rising, with an estimated million of deaths up to 2030.
Deepika Sharma +2 more
doaj +1 more source
Estrogen Receptor Expression in Glial Tumors of Iranian Patients: A Single Center Experience [PDF]
Iranian Journal of Pathology, 2020 Background & Objective:Gliomas are the most common type of primary intracranial tumors in adults. The expression of estrogen receptors varies in different grades of glial tumors, and some studies have suggested that this expression might have a ...
Masoumeh Shafiei +5 more
doaj +1 more source
BMC Cancer, 2009 Background Estrogen receptor-α (ERα) is essential for mammary gland development and is a major oncogene in breast cancer. Since ERα is not colocalized with the cell proliferation marker Ki-67 in the normal mammary glands and the majority of primary ...
Pan Zhongzong, Zhong Yili, Tan Huining
doaj +1 more source
Different approaches to unveil biomolecule configurations and their mutual interactions [PDF]
Analytical Letters 54, no.1-2, 40-56 (2020), 2020 A novel technique was demonstrated that overcome important drawbacks to crosslink cells by irradiation with ultrashort UV laser pulses (L-crosslinking). To use this technique coupled to Chromatin ImmunoPrecipitation (ChIP) in a high throughput context, a pre-screening fast method needs to be implemented to set up suitable irradiation conditions of the ...
arxiv +1 more source
European Journal of Medical Research, 2018 Background Although membrane-associated estrogen receptors (mERs) have been known to play important role in steroid-induced signal transmission, we still know little about their function in the estrogen-induced proliferation of breast cancer cells ...
Istvan Marczell +7 more
doaj +1 more source
Positive Regulation of Estrogen Receptor Alpha in Breast Tumorigenesis
Cells, 2021 Estrogen receptor alpha (ERα, NR3A1) contributes through its expression in different tissues to a spectrum of physiological processes, including reproductive system development and physiology, bone mass maintenance, as well as cardiovascular and central ...
Lucas Porras +2 more
doaj +1 more source
Nature Communications, 2022 Estrogen secreted by the ovary controls how the brain drives pulsatile reproductive hormone secretion. The authors show that in mice, estrogen receptor alpha within a specific population of hypothalamic kisspeptin neurons is the principal pathway through
H. James McQuillan +8 more
doaj +1 more source
Regulatory effect of gut microbes on blood pressure
Animal Models and Experimental Medicine, Volume 5, Issue 6, Page 513-531, December 2022., 2022 The interaction between gut microbiota and hypertension, the genera which affect the blood pressure in taxonomic level, and the commonly used treatments to hypertension based on the gut microbes were summarized in this review. The increases of Lactobacillus, etc.
Dong Yan +6 more
wiley +1 more source