Results 11 to 20 of about 154,423 (349)

Pharmacological inhibition of KDM1A/LSD1 enhances estrogen receptor beta-mediated tumor suppression in ovarian cancer. [PDF]

Cancer Lett, 2023
Venkata PP, Jayamohan S, He Y, Alejo S, Johnson JD, Palacios BE, Pratap UP, Chen Y, Liu Z, Zou Y, Lai Z, Suzuki T, Viswanadhapalli S, Weintraub ST, Palakurthi S, Valente PT, Tekmal RR, Kost ER, Vadlamudi RK, Sareddy GR.   +19 more
europepmc   +3 more sources

SAT-299 Growth Suppression of Triple-negative Breast Cancer Cells By the Cholesterol Biosynthesis Inhibitor RO 48-8071 is Associated With Induction of Estrogen Receptor-Beta [PDF]

J Endocr Soc
Yayun Liang, Salman M. Hyder
europepmc   +3 more sources

Estrogen receptor beta in the central amygdala regulates the deleterious behavioral and neuronal consequences of repeated social stress in female rats. [PDF]

Neurobiol Stress, 2023
Smiley CE, Pate BS, Bouknight SJ, Francis MJ, Nowicki AV, Harrington EN, Wood SK.   +6 more
europepmc   +2 more sources

Coumestrol Alleviates Oxidative Stress, Apoptosis and Cognitive Impairments Through Hippocampal Estrogen Receptor-Beta in Male Mouse Model of Chronic Restraint Stress [PDF]

Pharmaceutical Sciences, 2022
Background: Coumestrol is well-known as a natural estrogen receptor-beta modulator. Since the role of estrogen receptors in controlling stressful situations has already been reported and their cognitive functions in hippocampus seem to be independent of ...
Kiarash Fekri, Javad Mahmoudi, Saeed Sadigh-Eteghad, Fereshteh Farajdokht, Alireza Mohajjel Nayebi   +4 more
doaj   +1 more source

Role of estrogen receptors in cancer: a special emphasis on the therapeutic potential of estrogen receptor β [PDF]

Pharmaceutical Sciences Asia, 2022
Estrogen receptors are nuclear receptors that play a major role in both physiology and pathology. Estrogen receptor subtypes are currently divided into three groups: estrogen receptor alpha (ERα), estrogen receptor beta (ERβ), and G protein-coupled ...
Emdormi Rymbai, Deepa Sugumar, Dhritiman Roy, Divakar Selvaraj   +3 more
doaj   +1 more source

Cyclopia extracts act as selective estrogen receptor subtype downregulators in estrogen receptor positive breast cancer cell lines: Comparison to standard of care breast cancer endocrine therapies and a selective estrogen receptor agonist and antagonist

Frontiers in Pharmacology, 2023
Breast cancer is the most diagnosed type of cancer amongst women in economically developing countries and globally. Most breast cancers express estrogen receptor alpha (ERα) and are categorized as positive (ER+) breast cancer. Endocrine therapies such as,
Folasade R. Olayoku, Nicolette J. D. Verhoog, Ann Louw   +2 more
doaj   +1 more source

Immunohistochemical Expression of Estrogen Receptor Beta in Urothelial Carcinoma of the Urinary Bladder

SVU - International Journal of Medical Sciences, 2023
Background: The tenth most prevalent cancer type in the world is bladder cancer. Males are four times more likely than females to have it. The most prevalent subtype is urothelial carcinoma. Development and progression of bladder cancer are influenced by
Omnia M.M. Badawy *, Sabah Ahmed Mohamed, Ahmed Mahmoud Hassan , Ghada Hosny Mohamed   +3 more
doaj   +1 more source

Estrogen Signaling via Estrogen Receptor β [PDF]

Journal of Biological Chemistry, 2010
Estrogens act by binding to and activating two estrogen receptors (ERs), ERα and ERβ. Transcriptional regulation by ERs is controlled by a complex array of factors such as ER-ligand binding, the DNA sequence bound by ERs, ER-interacting cofactors, and chromatin context.
Chunyan, Zhao, Karin, Dahlman-Wright, Jan-Åke, Gustafsson   +2 more
openaire   +2 more sources

Analysis of Four Polymorphisms Located at the Promoter of the Estrogen Receptor Alpha ESR1 Gene in a Population With Gender Incongruence [PDF]

, 2020
[Abstract] Introduction: Gender incongruence defines a state in which individuals feel discrepancy between the sex assigned at birth and their gender. Some of these people make a social transition from male to female (transwomen) or from female to male ...
Almaraz, Mari Cruz, Cortés-Cortés, Joselyn, Delgado-Zayas, Enrique, Esteva, Isabel, Fernández, Rosa, Guillamón, Antonio, Gómez-Gil, Esther, Pásaro, Eduardo, Ramírez, Karla   +8 more
core   +1 more source

Functional characteristics of a novel murine estrogen receptor-beta isoform, estrogen receptor-beta 2 [PDF]

Journal of Molecular Endocrinology, 2000
We have isolated a highly expressed splice variant mRNA of murine estrogen receptor-beta (ERbeta), mERbeta2, containing an in-frame 54 nucleotide insertion between exons 5 and 6 of wild-type mERbeta1. The predicted ERbeta2 protein contains 18 amino acids inserted in the ligand binding domain of mERbeta1.
Lu, B., Leygue, E., Dotzlaw, H., Murphy, L. J., Murphy, L. C.   +4 more
openaire   +2 more sources