Results 271 to 280 of about 78,354 (303)

Alfa and beta estrogen receptors and the biliary tree

Molecular and Cellular Endocrinology, 2002
This manuscript summarizes recent data showing that estrogens and their receptors play an important role in modulating cholangiocyte proliferation. We have recently demonstrated that rat cholangiocytes express both estrogen receptors (ER)-alpha and -beta subtypes, while hepatocytes only express ER-alpha.
ALVARO, Domenico, G. Alpini, ONORI, PAOLO, FRANCHITTO, Antonio, S. S. Glaser, G. Le Sage, F. Folli, ATTILI, Adolfo Francesco, GAUDIO, EUGENIO   +8 more
openaire   +4 more sources

ESTROGEN RECEPTOR BETA TYPE IN THE RAT URINARY BLADDER

Archives of Andrology, 2006
This study was conducted to localize estrogen receptor beta (ERbeta) in the rat urinary bladder respect to gender. The bladder dome and trigone of 16 Sprague Dawley rats (Male: 8, Female: 8) were evaluated utilizing the reverse transcriptase-polymerase chain reaction technique (RT-PCR) to detect ERbeta signal.
Eliçevik, Mehmet, Horasanli, Sibel, Okaygün, Eda, Badur, Selim, Celayir, Sinan   +4 more
openaire   +3 more sources

Ontogeny of estrogen receptor-beta expression in rat testis.

Endocrinology, 1999
The recently discovered estrogen receptor-beta (ERbeta) is expressed in rodent and human testes. To obtain insight in the physiological role of ERbeta we have investigated the cell type-specific expression pattern of ERbeta messenger RNA (mRNA) and protein in the testis of rats of various ages by in situ hybridization and immunohistochemistry. In fetal
van Pelt, A. M., de rooij, D. G., van der Burg, B., van der Saag, P. T., Gustafsson, J. A., Kuiper, G. G.   +5 more
openaire   +3 more sources

Estrogen receptor β and breast cancer

European Journal of Surgical Oncology (EJSO), 2004
A second estrogen receptor, estrogen receptor-beta, was identified in 1996 and has led to an intensive re-evaluation of the role of estrogens in normal physiological and disease processes. While much has been learnt about this new receptor, there remain many outstanding questions, particularly regarding its prognostic significance and therapeutic ...
P J, Balfe, A H, McCann, H M, Welch, M J, Kerin   +3 more
openaire   +2 more sources

Estrogen receptor beta in breast cancer.

Endocrine-related cancer, 2002
Estrogen is essential for normal growth and differentiation in the mammary gland. It also supports growth of approximately 50% of primary breast cancers. For this reason, removal of estrogen or blocking of its action with the anti-estrogen, tamoxifen, is the main treatment for estrogen receptor alpha (ERalpha)-positive tumors. In 1996, when oncologists
C, Palmieri, G J, Cheng, S, Saji, M, Zelada-Hedman, A, Wärri, Z, Weihua, S, Van Noorden, T, Wahlstrom, R C, Coombes, M, Warner, J-A, Gustafsson   +10 more
openaire   +2 more sources

Challenging estrogen receptor β with phosphorylation

Trends in Endocrinology & Metabolism, 2010
From classical gland-based endocrinology to nuclear hormone receptor biology, tremendous progress has been made in our understanding of hormone responses underlying cellular communication. Estrogen elicits a myriad of biological processes in reproductive and peripheral target tissues through its interaction with the estrogen receptors ERalpha and ...
Mélanie, Sanchez, Nathalie, Picard, Karine, Sauvé, André, Tremblay   +3 more
openaire   +2 more sources

Photoperiod affects estrogen receptor alpha, estrogen receptor beta and aggressive behavior.

The European journal of neuroscience, 2007
Estrogens have important effects on male and female social behavior. Despite growing knowledge of the anatomy and behavioral effects of the two predominant estrogen receptor subtypes in mammals (ERalpha and ERbeta), relatively little is known about how these receptors respond to salient environmental stimuli. Many seasonally breeding species respond to
Brian C, Trainor, Michael R, Rowland, Randy J, Nelson   +2 more
openaire   +2 more sources

Estrogen receptor beta in the prostate

Molecular and Cellular Endocrinology, 2002
Zhang, Weihua, Margaret, Warner, Jan-Ake, Gustafsson   +2 more
openaire   +2 more sources

Estrogen receptor beta in health and disease.

Biology of reproduction, 2006
Estrogens, acting through its two receptors, ESR1 (hereafter designated ER alpha) and ESR2 (hereafter designated ER beta), have diverse physiological effects in the reproductive system, bone, cardiovascular system, hematopoiesis, and central and peripheral nervous systems.
Otabek, Imamov, Gil-Jin, Shim, Margaret, Warner, Jan-Ake, Gustafsson   +3 more
openaire   +1 more source

Estrogen receptor-beta: a new form of estrogen receptor in breast cancer

European Journal of Cancer, 1999
R. Cullen, T.M. Maguire, E. McDermott, N. O'Higgins, M.J. Duffy   +4 more
openaire   +1 more source