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Estrogen receptor transcription and transactivation Estrogen receptor alpha and estrogen receptor beta: regulation by selective estrogen receptor modulators and importance in breast cancer [PDF]
Breast Cancer Research, 2000 Estrogens display intriguing tissue-selective action that is of great biomedical importance in the development of optimal therapeutics for the prevention and treatment of breast cancer, for menopausal hormone replacement, and for fertility regulation. Certain compounds that act through the estrogen receptor (ER), now referred to as selective estrogen ...
S Katzenellenbogen, Benita +1 more
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Mitochondrial localization of estrogen receptor β [PDF]
Proceedings of the National Academy of Sciences, 2004 Estrogen receptors (ERs) are believed to be ligand-activated transcription factors belonging to the nuclear receptor superfamily, which on ligand binding translocate into the nucleus and activate gene transcription. To date, two ERs have been identified: ERα and ERβ.
Shao-Hua, Yang +11 more
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Genistein as an Estrogen Receptor-Beta Selective Phytoestrogen: Molecular Docking Insights for Advanced Wound Healing Therapies [PDF]
BIO Web of ConferencesWound healing is highly hormonal based and is stepwise process involving inflammation, proliferation, and remodeling .Estrogen is a key regulator having two receptor subtypes having various functions.
Varma Greeshma +2 more
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Expression levels of sex hormone receptors in brains ofJapanese medaka, Oryzias latipes (Actinopterygii: Beloniformes: Adrianichthyidae) [PDF]
Acta Ichthyologica et Piscatoria, 2011 Background. In teleost fishes, the brain is the target organ for sex steroid hormones. The actions of sex steroid hormones are mediated by their receptors and play an important role in the regulation of endocrine function in the brain.
A. Ngamniyom, Y. Sasayama
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Synthesis and Evaluation of (1,4-Disubstituted)-1,2,3-triazoles as Estrogen Receptor Beta Agonists
Scientia Pharmaceutica, 2022 Estrogen receptors (ER) are nuclear hormone receptors which are responsible for sex hormone signaling in women. A series of (1,4-disubstituted)-1,2,3-triazoles 5–21 were prepared by reaction of azidophenols with terminal alkynes under Fokin reaction ...
Edward A. Wetzel +4 more
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ESR2 (Estrogen Receptor 2 (ER beta) ) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on ESR2 (Estrogen Receptor 2 (ER beta) ), with data on DNA, on the protein encoded, and where the gene is implicated.
Zhao, C +2 more
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Folia Histochemica et Cytobiologica, 2010 The biology of breast cancer is closely releted to sex steroid hormones. Estrogen receptor beta is overexpressed in around 70% breast cancer cases, referrd to as "ER positive".
Mariusz Kuźmicki +6 more
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Reproductive Biology and Endocrinology, 2009 Background Estrogen is known to play role in temporomandibular joint (TMJ) disorders and estrogen effects can be mediated by estrogen receptor (ER) alpha present in the TMJ.
Bellinger Larry L +3 more
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Role of estrogen receptors in health and disease
Frontiers in Endocrinology, 2022 Estrogen receptors (ERs) regulate multiple complex physiological processes in humans. Abnormal ER signaling may result in various disorders, including reproductive system-related disorders (endometriosis, and breast, ovarian, and prostate cancer), bone ...
Peng Chen, Bo Li, Ling Ou-Yang
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Frontiers in Cellular Neuroscience, 2021 Estrogens and estrogen-like molecules can modify the biology of several cell types. Estrogen receptors alpha (ERα) and beta (ERβ) belong to the so-called classical family of estrogen receptors, while the G protein-coupled estrogen receptor 1 (GPER-1 ...
Felipe A. Bustamante-Barrientos +14 more
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