Peripheral and central mechanisms involved in hormonal control of male and female reproduction [PDF]
, 2016 Reproduction involves the integration of hormonal signals acting across multiple systems togenerate a synchronized physiological output. A critical component of reproduction is the luteinizinghormone (LH) surge, which is mediated by estradiol (E2) and ...
Bentley, G. E. +6 more
core +1 more source
Proceedings, 2019 Estrogen receptor-beta (ER-beta) is a drug target for memory consolidation in postmenopausal [...]
Alicia M. Hanson +10 more
doaj +1 more source
Estrogen receptor beta in breast cancer
Molecular and Cellular Endocrinology, 2014 Estrogen is essential for growth and development of the mammary glands and has been associated with the promotion and growth of breast cancer and in line with this, most human breast cancers are initially estrogen-dependent and undergo regression when deprived of their supporting hormone.
Haldosén, Lars-Arne +2 more
openaire +2 more sources
Estrogen receptor transcription and transactivation Estrogen receptor alpha and estrogen receptor beta: regulation by selective estrogen receptor modulators and importance in breast cancer [PDF]
Breast Cancer Research, 2000 Estrogens display intriguing tissue-selective action that is of great biomedical importance in the development of optimal therapeutics for the prevention and treatment of breast cancer, for menopausal hormone replacement, and for fertility regulation. Certain compounds that act through the estrogen receptor (ER), now referred to as selective estrogen ...
S Katzenellenbogen, Benita +1 more
openaire +2 more sources
Roles of estrogen receptor-alpha in mediating life span: the hypothalamic deregulation hypothesis. [PDF]
, 2017 In several species caloric restriction (CR) extends life span. In this paper we integrate data from studies on CR and other sources to articulate the hypothalamic deregulation hypothesis by which estrogen receptor-alpha (ER-α) signaling in the ...
Barakat, Rita +6 more
core +1 more source
Estrogen/estrogen receptor alpha signaling in mouse posterofrontal cranial suture fusion. [PDF]
PLoS ONE, 2009 While premature suture fusion, or craniosynostosis, is a relatively common condition, the cause is often unknown. Estrogens are associated with growth plate fusion of endochondral bones.
Aaron W James +8 more
doaj +1 more source
Mitochondrial localization of estrogen receptor β [PDF]
Proceedings of the National Academy of Sciences, 2004 Estrogen receptors (ERs) are believed to be ligand-activated transcription factors belonging to the nuclear receptor superfamily, which on ligand binding translocate into the nucleus and activate gene transcription. To date, two ERs have been identified: ERα and ERβ.
Shao-Hua, Yang +11 more
openaire +2 more sources
Genistein as an Estrogen Receptor-Beta Selective Phytoestrogen: Molecular Docking Insights for Advanced Wound Healing Therapies [PDF]
BIO Web of ConferencesWound healing is highly hormonal based and is stepwise process involving inflammation, proliferation, and remodeling .Estrogen is a key regulator having two receptor subtypes having various functions.
Varma Greeshma +2 more
doaj +1 more source
Expression levels of sex hormone receptors in brains ofJapanese medaka, Oryzias latipes (Actinopterygii: Beloniformes: Adrianichthyidae) [PDF]
Acta Ichthyologica et Piscatoria, 2011 Background. In teleost fishes, the brain is the target organ for sex steroid hormones. The actions of sex steroid hormones are mediated by their receptors and play an important role in the regulation of endocrine function in the brain.
A. Ngamniyom, Y. Sasayama
doaj +3 more sources
Labor-associated gene expression in the human uterine fundus, lower segment, and cervix [PDF]
, 2006 Background Preterm labor, failure to progress, and postpartum hemorrhage are the common causes of maternal and neonatal mortality or morbidity. All result from defects in the complex mechanisms controlling labor, which coordinate changes in the ...
Aguan +37 more
core +3 more sources