Results 141 to 150 of about 2,557,731 (353)
Interfacial Stress Regulates Plasticity and Drug Resistance at the Breast Cancer‐Host Interface
Advanced Science, EarlyView.Drop‐on‐demand printing is used to replicate the spatial compartmentalization of the breast cancer‐host interface. Hydrogel confinement affects phenotypic changes in cells at the spheroid interface that drives a two‐fold increase in chemotherapeutic resistance compared to control unconfined spheroids.
Bram G. Soliman +4 more
wiley +1 more source
Advanced Science, EarlyView.In this study, it is found that osteoporosis leads to disturbances in the Extracellular Matrix (ECM)of tendons and thus causes a decrease in TSPC stemness, resulting in a rotator cuff that is easily damaged and prone to retearing after repair. Targeted intervention with si‐CD248‐loaded liposomes can restore TSPC stemness, promote tendon‐bone healing ...
Yinhua Qian +14 more
wiley +1 more source
Editorial: Estrogen receptors in endocrine disorders. [PDF]
Front Endocrinol (Lausanne), 2023 Filardi T +3 more
europepmc +1 more source
Comprehensive genetic analysis of poorly differentiated gastric cancer in young females
Annals of Gastroenterological Surgery, EarlyView.Although the involvement of female sex hormones in the development of poorly differentiated gastric cancer in young females is controversial, our detailed analysis using RNA‐seq suggested that the female sex hormone, β‐estradiol plays a role in the development of poorly differentiated gastric cancer in young females. Abstract Aim The reasons behind the
Nobuhiro Nakazawa +9 more
wiley +1 more source
Machine‐Learning‐Guided Analysis of Breast Tumor Malignancy Based on Nuclear Morphological Features
Advanced Intelligent Discovery, EarlyView.Through statistical and machine learning approaches, we evaluate a clinically relevant dataset comprising more than 500 instances of patient breast tumor nuclei with 10 size and shape features. Our study underscores the significance of nuclear morphological features as potential breast tumor malignancy biomarkers and their combined use with statistical
Aditi Birwadkar +3 more
wiley +1 more source
Advanced Intelligent Discovery, EarlyView.Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz +2 more
wiley +1 more source
Increased vascular catecholamine sensitivity and alpha-adrenergic receptor affinity in female and estrogen-treated male rats. [PDF]
, 1982 Wilson S. Colucci +4 more
openalex +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Cardiac rhabdomyomas are often the presenting sign of tuberous sclerosis complex (TSC). Prior reports have shown that maternal sirolimus treatment can reduce rhabdomyomas. We used maternal sirolimus to reverse hydrops fetalis due to a massive cardiac rhabdomyoma in a twin gestation.
David M. Ritter +6 more
wiley +1 more source