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The Role of Estrogen Receptors in Cardiovascular Disease
International Journal of Molecular Sciences, 2020 Cardiovascular Diseases (CVDs) are the leading cause of death globally. More than 17 million people die worldwide from CVD per year. There is considerable evidence suggesting that estrogen modulates cardiovascular physiology and function in both health ...
Laila Aryan +9 more
semanticscholar +1 more source
The Role of Estrogen Receptors and Their Signaling across Psychiatric Disorders
International Journal of Molecular Sciences, 2020 Increasing evidence suggests estrogen and estrogen signaling pathway disturbances across psychiatric disorders. Estrogens are not only crucial in sexual maturation and reproduction but are also highly involved in a wide range of brain functions, such as ...
W. Hwang +3 more
semanticscholar +1 more source
Estrogen Receptors and Endothelium [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2010 Estrogens, and in particular 17β-estradiol (E2), play a pivotal role in sexual development and reproduction and are also implicated in a large number of physiological processes, including the cardiovascular system. Both acetylcholine-induced and flow-dependent vasodilation are preserved or potentiated by estrogen treatment in both animal models and ...
Arnal, Jean-François +6 more
openaire +4 more sources
Estrogens and the risk of breast cancer: A narrative review of literature
Heliyon, 2023 In female mammals, the development and regulation of the reproductive system and non-reproductive system are significantly influenced by estrogens (oestrogens). In addition, lipid metabolism is another physiological role of estrogens.
Khayry Al-Shami +10 more
doaj +1 more source
Regenerating Rat Liver: Correlations Between Estrogen Receptor Localization and Deoxyribonucleic Acid Synthesis [PDF]
, 1984 Estrogen receptor activity was quantitated in the cytosol and nucleus of normal rat liver and in regenerating rat liver at several time intervals after 75% hepatectomy. Cytosolic estradiol binding in regenerating liver decreases at 12, 24, and 48 h after
Di Leo, A +6 more
core +1 more source
The Role of G Protein-Coupled Estrogen Receptor (GPER) in Vascular Pathology and Physiology
Biomolecules, 2023 Objective: Estrogen is indispensable in health and disease and mainly functions through its receptors. The protection of the cardiovascular system by estrogen and its receptors has been recognized for decades.
Fujie Xu +7 more
doaj +1 more source
Estrogen, Estrogen Receptor and Lung Cancer [PDF]
International Journal of Molecular Sciences, 2017 Estrogen has been postulated as a contributor for lung cancer development and progression. We reviewed the current knowledge about the expression and prognostic implications of the estrogen receptors (ER) in lung cancer, the effect and signaling pathway of estrogen on lung cancer, the hormone replacement therapy and lung cancer risk and survival, the ...
Li-Han Hsu, Nei-Min Chu, Shu-Huei Kao
openaire +3 more sources
Estrogen, angiogenesis, immunity and cell metabolism: Solving the puzzle [PDF]
, 2018 Estrogen plays an important role in the regulation of cardiovascular physiology and the immune system by inducing direct effects on multiple cell types including immune and vascular cells. Sex steroid hormones are implicated in cardiovascular protection,
Bolego, Chiara +5 more
core +2 more sources
Immunohistochemical detection of estrogen and progesterone receptors in the human lacrimal gland [PDF]
Archives of Biological Sciences, 2011 The nature and extent of estrogen and progesterone action on the lacrimal gland is not known, and neither are the targets for their action. Immunohistochemical detection of estrogen and progesterone receptors in the human lacrimal glands in both sexes
Gligorijević Jasmina +2 more
doaj +1 more source
A Basic Review on Estrogen Receptor Signaling Pathways in Breast Cancer
International Journal of Molecular Sciences, 2023 Breast cancer is the most common cancer and the deadliest among women worldwide. Estrogen signaling is closely associated with hormone-dependent breast cancer (estrogen and progesterone receptor positive), which accounts for two-thirds of tumors. Hormone
Léa Clusan +3 more
semanticscholar +1 more source