Results 41 to 50 of about 2,557,731 (353)

The steroid hormone estriol (E3) regulates epigenetic programming of fetal mouse brain and reproductive tract

open access: yesBMC Biology, 2022
Background Estriol (E3) is a steroid hormone formed only during pregnancy in primates including humans. Although E3 is synthesized at large amounts through a complex pathway involving the fetus and placenta, it is not required for the maintenance of ...
Yuping Zhou   +13 more
doaj   +1 more source

Molecular Imaging Provides Novel Insights on Estrogen Receptor Activity in Mouse Brain

open access: yesMolecular Imaging, 2008
Estrogen receptors have long been known to be expressed in several brain areas in addition to those directly involved in the control of reproductive functions.
Alessia Stell   +3 more
doaj   +1 more source

Estrogen stimulates adenosine receptor expression subtypes in human breast cancer MCF-7 cell line

open access: yesResearch in Pharmaceutical Sciences, 2018
Estrogen is a steroid hormone that plays a key role in the development and regulation of reproductive system. It has been shown that estrogen is related to breast cancer development through binding to its receptors.
Azam Mohamadi   +2 more
doaj   +1 more source

Estrogen modulation of pain perception with a novel 17β-estradiol pretreatment regime in ovariectomized rats

open access: yesBiology of Sex Differences, 2020
Estrogen plays substantial roles in pain modulation; however, studies concerning sex hormones and nociception often yield confusing results. The discrepancy could be a result of lack of consensus to regard estrogen as a variable when working with animal ...
Wenxin Zhang   +10 more
doaj   +1 more source

Estrogen metabolism: why it’s so crucial to keep the balance?

open access: yesГинекология, 2020
Aim. To analyze and systematize the available information on pathogenetic mechanisms of hormonal carcinogenesis. Materials and methods. The review includes data from foreign articles published in PubMed and Medline and national works posted on ...
Oksana V. Yakushevskaya   +2 more
doaj   +1 more source

Silibinin protects GLUTag cells from PA-induced injury via suppressing endoplasmic reticulum stress

open access: yesCyTA - Journal of Food, 2023
Silibinin is a natural flavonoid with anti-diabetic activity. Glucagon-like peptide−1 (GLP−1), an intestinal hormone mainly secreted from L cells, which regulates insulin production and sensitivity, appears to be a potential therapeutic strategy for T2DM.
Xinyi Shi   +9 more
doaj   +1 more source

Endocrine Disruptors Acting on Estrogen and Androgen Pathways Cause Reproductive Disorders through Multiple Mechanisms: A Review

open access: yesInternational Journal of Environmental Research and Public Health, 2021
Increasing contamination of the environment by toxic compounds such as endocrine disrupting chemicals (EDCs) is one of the major causes of reproductive defects in both sexes.
S. Amir   +10 more
semanticscholar   +1 more source

Estrogen Receptor β

open access: yesArchives of Pathology & Laboratory Medicine, 2011
Abstract Context—A new class of estrogen receptors was discovered in 1996 and named estrogen receptor β (ER-B); the traditional estrogen receptor, which until a little more than 10 years ago was thought of as the only estrogen receptor in existence, is now called estrogen receptor α. Estrogen receptor β has at least 5 isoforms, which may
Mamoun Younes, Naoko Honma
openaire   +3 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Estrogen and estrogen receptors in the modulation of gastrointestinal epithelial secretion

open access: yesOncoTarget, 2017
Gastrointestinal (GI) epithelial ion transport is physiologically important in many aspects of humans, such as in maintaining fluid balance of whole body, and also plays a role in the development and progression of common GI disease.
Xin Yang   +6 more
semanticscholar   +1 more source

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