Results 11 to 20 of about 484,096 (391)
Structural plasticity of the hippocampus in response to estrogens in female rodents
Molecular Brain, 2019 It is well established that estrogens affect neuroplasticity in a number of brain regions. In particular, estrogens modulate and mediate spine and synapse formation as well as neurogenesis in the hippocampal formation.
Paul A. S. Sheppard +2 more
doaj +2 more sources
Molecular mechanism of estrogen–estrogen receptor signaling [PDF]
Reproductive Medicine and Biology, 2016 Abstract17β‐Estradiol (E2), as the main circulating estrogen hormone, regulates many tissue and organ functions in physiology. The effects of E2 on cells are mediated by the transcription factors and estrogen receptor (ER)α and ERβ that are encoded by distinct genes.
Pelin Yaşar +4 more
openalex +4 more sources
Estrogen and estrogen receptors in kidney diseases [PDF]
Renal Failure, 2021 Acute kidney injury (AKI) and chronic kidney disease (CKD) are posing great threats to global health within this century. Studies have suggested that estrogen and estrogen receptors (ERs) play important roles in many physiological processes in the kidney.
Hao-Yang Ma, Shuang Chen, Yang Du
openaire +3 more sources
The Impact of Estrogens and Their Receptors on Immunity and Inflammation during Infection
Cancers, 2022 Simple Summary Human health is significantly affected by microbial infections. One of the largest determinants of the outcomes of such infections is the host immune response.
Alfred T. Harding, Nicholas S. Heaton
semanticscholar +1 more source
Role of Estrogens in Menstrual Migraine
Cells, 2022 Migraine is a major neurological disorder affecting one in nine adults worldwide with a significant impact on health care and socioeconomic systems. Migraine is more prevalent in women than in men, with 17% of all women meeting the diagnostic criteria ...
R. Nappi +5 more
semanticscholar +1 more source
International Journal of Molecular Sciences, 2021 Bone is a multi-skilled tissue, protecting major organs, regulating calcium phosphate balance and producing hormones. Its development during childhood determines height and stature as well as resistance against fracture in advanced age. Estrogens are key
N. Emmanuelle +6 more
semanticscholar +1 more source
Estrogens and the regulation of glucose metabolism
World Journal of Diabetes, 2021 The main estrogens: estradiol, estrone, and their acyl-esters have been studied essentially related to their classical estrogenic and pharmacologic functions.
M. Alemany
semanticscholar +1 more source
Estrogens and environmental estrogens
Biomedicine & Pharmacotherapy, 2002 The natural female sex hormone estrogens binds once inside the cell to a protein receptor to form a 'ligand-hormone receptor complex'. The binding activates the hormone receptor, which triggers specific cellular processes. The activated hormone receptor then turns on specific genes, causing cellular changes that lead to responses typical of a ligand ...
H, Tapiero, G Nguyen, Ba, K D, Tew
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The binding of estrogen and estrogen antagonists to the estrogen receptor
Archives of Biochemistry and Biophysics, 1992 The model of the estrogen receptor as a dimer of identical, interacting subunits and data obtained by Sasson and Notides (1988, Mol. Endocrinol. 2, 307-312) were used to find the standard free energy changes that describe the binding of estradiol and 4-hydroxytamoxifen to the estrogen receptor.
J P, Bond, S, Sasson, A C, Notides
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Estrogen-Independent Activation of Estrogen Receptors [PDF]
Hypertension, 2011 See related article, pp 1161–1166 Sex differences showing a lower prevalence and better outcome after ischemic stroke in women have been described, differences that are abrogated by natural or surgical menopause.1,2 High levels of endogenous estrogens in premenopausal women have been associated with reduced risk for a number of diseases, such as ...
Matthias, Barton +2 more
openaire +2 more sources