Results 11 to 20 of about 135,506 (195)

Estrogens promote misfolded proinsulin degradation to protect insulin production and delay diabetes [PDF]

, 2018
Summary: Conjugated estrogens (CE) delay the onset of type 2 diabetes (T2D) in postmenopausal women, but the mechanism is unclear. In T2D, the endoplasmic reticulum (ER) fails to promote proinsulin folding and, in failing to do so, promotes ER stress and
Allard, Camille, Alvarez-Mercado, Ana I, Arvan, Peter, Coons, Laurel A, Floyd, Z. Elizabeth, Fuselier, Taylor, Hewitt, Sylvia C, Kim, Jun Ho, Korach, Kenneth S, Levin, Ellis R, Mauvais-Jarvis, Franck, Urano, Fumihiko, Xu, Beibei   +12 more
core   +2 more sources

Influence of operating parameters on the biodegradation of steroid estrogens and nonylphenolic compounds during biological wastewater treatment processes [PDF]

, 2009
This document is the unedited author's version of a Submitted Work that was subsequently accepted for publication in Environmental Science & Technology, copyright © American Chemical Society after peer review.
Ahel M., Andersen H., Baronti C., Belfroid A. C., Birkett J. W., Burke M., Carballa M., Carballa M., Chiu T. Y., Clara M., Davenport R. J., D’Ascenzo G., Fürhacker M., Gaulk L. S., Giger W., Gomes R. L., Gomes R. L., Gomes R. L., Graham D. W., Holbrook R. D., Ifelebuegu A. O., Janex-Habibi M. L., Jobling S., Jobling S., Johnson A. C., Johnson A. C., Jones O. A. H., Joss A., Kirk L. A., Koh K., Koh Y. K. K., Koh Y. K. K., Koh Y. K. K., Kreuzinger N., Lagana A., Lai K. M., Lai K. M., Langford K., Langford K. H., Loyo-Rosales J. E., Nakada N., Obeng L. A., Onda K., Quinlivan P. A., Ren Y.-X., Renner R., Rosenfeldt E. J., Routledge E. J., Servos M. R., Snyder S. A., Stephenson T., Svenson A., Ternes T. A., Ternes T. A., Ternes T. A., Vader J. S.   +55 more
core   +1 more source

Estrogens and environmental estrogens

Biomedicine & Pharmacotherapy, 2002
The natural female sex hormone estrogens binds once inside the cell to a protein receptor to form a 'ligand-hormone receptor complex'. The binding activates the hormone receptor, which triggers specific cellular processes. The activated hormone receptor then turns on specific genes, causing cellular changes that lead to responses typical of a ligand ...
H, Tapiero, G Nguyen, Ba, K D, Tew
openaire   +2 more sources

Disruption of 3D MCF-12A breast cell cultures by estrogens - An in vitro model for ER-mediated changes indicative of hormonal carcinogenesis [PDF]

, 2012
Copyright @ 2012 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and 85 reproduction in any medium, provided the original author and source
Elisabete Silva, Irina Agoulnik, Stephanie Marchese   +2 more
core   +4 more sources

Potential role of the interaction between equine estrogens, low-density lipoprotein (LDL) and high-density lipoprotein (HDL) in the prevention of coronary heart and neurodegenerative diseases in postmenopausal women

Lipids in Health and Disease, 2003
Background An inverse relationship between the level of high-density lipoprotein (HDL) and coronary heart disease (CHD) has been reported. In contrast, oxidized HDL (oHDL) has been shown to induce neuronal death and may play an important role in the ...
Gerulath Alan, Cecutti Anthony, Berco Mauricio, Perrella Joel, Bhavnani Bhagu R   +4 more
doaj   +1 more source

Neuronal differentiation dictates estrogen-dependent survival and ERK1/2 kinetic by means of caveolin-1. [PDF]

PLoS ONE, 2014
Estrogens promote a plethora of effects in the CNS that profoundly affect both its development and mature functions and are able to influence proliferation, differentiation, survival and neurotransmission.
Floriana Volpicelli, Massimiliano Caiazzo, Bruno Moncharmont, Umberto di Porzio, Luca Colucci-D'Amato   +4 more
doaj   +1 more source

Estrogenic activity, race/ethnicity, and Indigenous American ancestry among San Francisco Bay Area women. [PDF]

, 2019
Estrogens play a significant role in breast cancer development and are not only produced endogenously, but are also mimicked by estrogen-like compounds from environmental exposures.
Fejerman, Laura, Gomez, Scarlett L, John, Esther M, Sanchez, Sylvia S, Smith, Martyn T, Stanczyk, Frank Z, Tachachartvanich, Phum   +6 more
core   +2 more sources

Oral contraceptives combined with interferon β in multiple sclerosis [PDF]

, 2015
Objective: To test the effect of oral contraceptives (OCs) in combination with interferon b (IFN-b) on disease activity in patients with relapsing-remitting multiple sclerosis (RRMS).
Barletta, Valeria T., De Angelis, Floriana, De Giglio, Laura, Gallo, Valentina, Marinelli, Fabiana, Marini, Stefano, Pagano, Veronica A., Pantano, Patrizia, Piattella, Maria C., Pozzilli, Carlo, Tomassini, Valentina   +10 more
core   +3 more sources

Effect of estrogens on boar sperm capacitation in vitro

Reproductive Biology and Endocrinology, 2010
Background Mammalian sperm must undergo a series of controlled molecular processes in the female reproductive tract called capacitation before they are capable of penetrating and fertilizing the egg.
Ded Lukas, Dostalova Pavla, Dorosh Andriy, Dvorakova-Hortova Katerina, Peknicova Jana   +4 more
doaj   +1 more source

Estrogens in Human Male Gonadotropin Secretion and Testicular Physiology From Infancy to Late Puberty

Frontiers in Endocrinology, 2020
Several reports in humans as well as transgenic mouse models have shown that estrogens play an important role in male reproduction and fertility. Estrogen receptor alpha (ERα) and beta (ERβ) are expressed in different male tissues including the brain ...
Gabriela Guercio, Gabriela Guercio, Nora Saraco, Nora Saraco, Mariana Costanzo, Roxana Marino, Pablo Ramirez, Esperanza Berensztein, Esperanza Berensztein, Marco A. Rivarola, Marco A. Rivarola, Alicia Belgorosky, Alicia Belgorosky   +12 more
doaj   +1 more source