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Estrogens in schizophrenia: What do we know?
Introduction Schizophrenia is a chronic disease that significantly impacts cognitive functioning. Sex differences in incidence, onset and course of schizophrenia suggest estrogens have a protective role.
L. Paulino Ferreira+3 more
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This paper presents a review of the major anatomical, biochemical and physiological effects of estrogens upon the kidney. The field awaits a careful, systematic and comprehensive study.
Nicholas P. Christy, Joyce C. Shaver
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Estrogenic plant extracts reverse weight gain and fat accumulation without causing mammary gland or uterine proliferation. [PDF]
Long-term estrogen deficiency increases the risk of obesity, diabetes and metabolic syndrome in postmenopausal women. Menopausal hormone therapy containing estrogens might prevent these conditions, but its prolonged use increases the risk of breast ...
Elise F Saunier+11 more
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Background Results of the Women's Health Initiative Memory Study (WHIMS) raised concerns regarding the timing and formulation of hormone interventions.
Brinton Roberta, Zhao Liqin
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Estrogen-Independent Activation of Estrogen Receptors [PDF]
See related article, pp 1161–1166 Sex differences showing a lower prevalence and better outcome after ischemic stroke in women have been described, differences that are abrogated by natural or surgical menopause.1,2 High levels of endogenous estrogens in premenopausal women have been associated with reduced risk for a number of diseases, such as ...
Matthias R. Meyer+2 more
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Molecular mechanism of estrogen–estrogen receptor signaling [PDF]
Abstract17β‐Estradiol (E2), as the main circulating estrogen hormone, regulates many tissue and organ functions in physiology. The effects of E2 on cells are mediated by the transcription factors and estrogen receptor (ER)α and ERβ that are encoded by distinct genes.
Yasar, Pelin+4 more
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The clinical utility of estrogens for treating prostate cancer (CaP) was established in the 1940s by Huggins. The classic model of the anti-CaP activity of estrogens postulates an indirect mechanism involving the suppression of androgen production ...
Ilsa M. Coleman+7 more
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Estrogen receptor cytochemistry by fluorescent estrogen. [PDF]
A recently synthesized fluorescein-labeled estrogen (17FE, 1-(N)-fluoresceinyl-estrone-thiosemicarbazone) interacts with estrogen-target cells like the native hormone and visualizes the uptake, transport, and distribution of estrogen in intact target cells.
G. Fabris+5 more
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AbstractBy regulating activities and expression levels of key signaling molecules, estrogens control mechanisms that are responsible for crucial cellular functions. Ligand binding to estrogen receptor (ER) leads to conformational changes that regulate the receptor activity, its interaction with other proteins and DNA.
Boris J. Cheskis+3 more
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There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes+20 more
wiley +1 more source