Results 21 to 30 of about 160,774 (316)

Estrogens in schizophrenia: What do we know?

open access: yesEuropean Psychiatry, 2021
Introduction Schizophrenia is a chronic disease that significantly impacts cognitive functioning. Sex differences in incidence, onset and course of schizophrenia suggest estrogens have a protective role.
L. Paulino Ferreira   +3 more
doaj   +1 more source

Estrogens and the kidney

open access: yesKidney International, 1974
This paper presents a review of the major anatomical, biochemical and physiological effects of estrogens upon the kidney. The field awaits a careful, systematic and comprehensive study.
Nicholas P. Christy, Joyce C. Shaver
openaire   +3 more sources

Estrogenic plant extracts reverse weight gain and fat accumulation without causing mammary gland or uterine proliferation. [PDF]

open access: yesPLoS ONE, 2011
Long-term estrogen deficiency increases the risk of obesity, diabetes and metabolic syndrome in postmenopausal women. Menopausal hormone therapy containing estrogens might prevent these conditions, but its prolonged use increases the risk of breast ...
Elise F Saunier   +11 more
doaj   +1 more source

Select estrogens within the complex formulation of conjugated equine estrogens (Premarin®) are protective against neurodegenerative insults: implications for a composition of estrogen therapy to promote neuronal function and prevent Alzheimer's disease

open access: yesBMC Neuroscience, 2006
Background Results of the Women's Health Initiative Memory Study (WHIMS) raised concerns regarding the timing and formulation of hormone interventions.
Brinton Roberta, Zhao Liqin
doaj   +1 more source

Estrogen-Independent Activation of Estrogen Receptors [PDF]

open access: yesHypertension, 2011
See related article, pp 1161–1166 Sex differences showing a lower prevalence and better outcome after ischemic stroke in women have been described, differences that are abrogated by natural or surgical menopause.1,2 High levels of endogenous estrogens in premenopausal women have been associated with reduced risk for a number of diseases, such as ...
Matthias R. Meyer   +2 more
openaire   +3 more sources

Molecular mechanism of estrogen–estrogen receptor signaling [PDF]

open access: yesReproductive Medicine and Biology, 2016
Abstract17β‐Estradiol (E2), as the main circulating estrogen hormone, regulates many tissue and organ functions in physiology. The effects of E2 on cells are mediated by the transcription factors and estrogen receptor (ER)α and ERβ that are encoded by distinct genes.
Yasar, Pelin   +4 more
openaire   +4 more sources

Inhibition of Androgen-Independent Prostate Cancer by Estrogenic Compounds Is Associated with Increased Expression of Immune-Related Genes

open access: yesNeoplasia: An International Journal for Oncology Research, 2006
The clinical utility of estrogens for treating prostate cancer (CaP) was established in the 1940s by Huggins. The classic model of the anti-CaP activity of estrogens postulates an indirect mechanism involving the suppression of androgen production ...
Ilsa M. Coleman   +7 more
doaj   +1 more source

Estrogen receptor cytochemistry by fluorescent estrogen. [PDF]

open access: yesJournal of Histochemistry & Cytochemistry, 1980
A recently synthesized fluorescein-labeled estrogen (17FE, 1-(N)-fluoresceinyl-estrone-thiosemicarbazone) interacts with estrogen-target cells like the native hormone and visualizes the uptake, transport, and distribution of estrogen in intact target cells.
G. Fabris   +5 more
openaire   +3 more sources

Signaling by estrogens [PDF]

open access: yesJournal of Cellular Physiology, 2007
AbstractBy regulating activities and expression levels of key signaling molecules, estrogens control mechanisms that are responsible for crucial cellular functions. Ligand binding to estrogen receptor (ER) leads to conformational changes that regulate the receptor activity, its interaction with other proteins and DNA.
Boris J. Cheskis   +3 more
openaire   +3 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

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