Biotransformation and bioconcentration of steroid estrogens by Chlorella vulgaris [PDF]
The biotransformation and bioconcentration of natural and synthetic steroid estrogens by Chlorella vulgaris were investigated using batch shaking experiments with incubation for 48 hours in the light or dark.
Lai, KM, Lester, JN, Scrimshaw, MD
core +2 more sources
Sequential recruitment and combinatorial assembling of multiprotein complexes in transcriptional activation [PDF]
In human cells, estrogenic signals induce cyclical association and dissociation of specific proteins with the DNA in order to activate transcription of estrogen-responsive genes. These oscillations can be modeled by assuming a large number of sequential reactions represented by linear kinetics with random kinetic rates.
arxiv +1 more source
Different approaches to unveil biomolecule configurations and their mutual interactions [PDF]
A novel technique was demonstrated that overcome important drawbacks to crosslink cells by irradiation with ultrashort UV laser pulses (L-crosslinking). To use this technique coupled to Chromatin ImmunoPrecipitation (ChIP) in a high throughput context, a pre-screening fast method needs to be implemented to set up suitable irradiation conditions of the ...
arxiv +1 more source
Disruption of 3D MCF-12A breast cell cultures by estrogens - An in vitro model for ER-mediated changes indicative of hormonal carcinogenesis [PDF]
Copyright @ 2012 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and 85 reproduction in any medium, provided the original author and source
Elisabete Silva+2 more
core +2 more sources
Effect of estrogens on boar sperm capacitation
Background Mammalian sperm must undergo a series of controlled molecular processes in the female reproductive tract called capacitation before they are capable of penetrating and fertilizing the egg.
Ded Lukas+4 more
doaj +1 more source
Estrogens in personal care products are harmful to customers. Conventional methods such as HPLC and LC-MS require tedious sample pretreatment and long analytical time.
Dongning Song+5 more
doaj +1 more source
Treatment and removal strategies for estrogens from wastewater [PDF]
Natural and synthetic steroidal estrogens (estrone, 17β-estradiol and 17α-ethinylestradiol) are endocrine disrupters, that are discharged consistently from the sewage treatment works into surface waters, thereby causing endocrine disrupting effects to ...
Boobis, AR+5 more
core +1 more source
Estrogens and Development [PDF]
The normal development of the genital organs of mammals, including humans, is under hormonal control. A role for the female sex hormone estrogen in this process is still unclear. However, exposure of experimental animals or humans to the potent exogenous estrogen, diethylstilbestrol (DES), results in persistent differentiation effects.
John A. McLachlan, Retha R. Newbold
openaire +4 more sources
Background An inverse relationship between the level of high-density lipoprotein (HDL) and coronary heart disease (CHD) has been reported. In contrast, oxidized HDL (oHDL) has been shown to induce neuronal death and may play an important role in the ...
Gerulath Alan+4 more
doaj +1 more source
The significance of sample mass in the analysis of steroid estrogens in sewage sludges and the derivation of partition coefficients in wastewaters [PDF]
Optimization of an analytical method for determination of steroid estrogens, through minimizing sample size, resulted in recoveries >84%, with relative standard deviations
A.R. Boobis+34 more
core +1 more source