Results 51 to 60 of about 160,774 (316)
Estrogens regulate the hepatic effects of Growth Hormone, a hormonal interplay with multiple fates
Frontiers in Endocrinology, 2013 The liver responds to estrogens and GH which are critical regulators of body growth, gender-related hepatic functions, and intermediate metabolism. The effects of estrogens on liver can be direct, through the direct actions of hepatic ER, or indirect ...
Leandro eFernandez-Perez +3 more
doaj +1 more source
Clinical and Translational Science, 2020 This network meta‐analysis was conducted to compare the efficacy of six interventions, including anti‐blocking agents, intrauterine contraceptive devices (IUDs), estrogens, intrauterine balloon, Foley catheter, and amnion graft for the prevention of ...
Qian Xiong, Tiansong Zhang, Shujun Su
doaj +1 more source
Metabolomic profiling unravels DNA adducts in human breast that are formed from peroxidase mediated activation of estrogens to quinone methides. [PDF]
PLoS ONE, 2013 Currently there are three major hypotheses that have been proposed for estrogen induced carcinogenicity, however exact etiology remains unknown. Based on the chemical logic, studies were undertaken to investigate if estrogens could generate quinone ...
Nilesh W Gaikwad
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Matrix Tropism Influences Endometriotic Cell Attachment Patterns
Advanced Functional Materials, EarlyView.The influence of substrate stiffness and multicellular coculture on endometriotic cell attachment to extracellular matrix‐laden microarrayed islands is reported. This model investigates early endometriotic cell attachment, aiming to capture “lesion initiation events”.
Hannah S. Theriault +7 more
wiley +1 more source
Scientific ReportsFerroptosis is a form of regulated cell death, characterized by excessive iron-dependent lipid peroxidation. Biochemically, ferroptosis can be selectively induced by erastin through glutathione depletion or through inhibition of glutathione peroxidase 4 ...
Xuanqi Huang, Ming-Jie Hou, Bao Ting Zhu
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The Influence of Estrogens on the Biological and Therapeutic Actions of Growth Hormone in the Liver
Pharmaceuticals, 2012 GH is main regulator of body growth and composition, somatic development, intermediate metabolism and gender-dependent dimorphism in mammals. The liver is a direct target of estrogens because it expresses estrogen receptors which are connected with ...
Leandro Fernández-Pérez +6 more
doaj +1 more source
Metal Nanoclusters for Cancer Imaging and Treatment
Advanced Functional Materials, EarlyView.This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu +5 more
wiley +1 more source
Potassium, magnesium and pyridoxine in the context of the biological effects of estrogens [PDF]
Гинекология, 2017 Potassium and magnesium ions are essential for realizing the biological effects of estrogens. Magnesium ions promote the translocation of the estrogen receptors into the nucleus of the cell and regulate the potassium channels that are involved in the ...
O A Gromova +4 more
doaj
Advanced Functional Materials, EarlyView.Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao +8 more
wiley +1 more source
Integration of Bioengineered Tools in Assisted Reproductive Technologies
Advanced Healthcare Materials, EarlyView.A conceptual illustration depicting the collaboration between a medical professional (right) and a scientist (left). Their connection highlights the integration of scientific research and clinical practice. This representation underscores the role of emerging technologies in bridging fundamental research with applied reproductive healthcare.
Aslı Ak +3 more
wiley +1 more source