Results 121 to 130 of about 115,949,529 (167)

Understanding the evolution and function of the mycobacterial Type VII ESX secretion systems (T7SSs) and their substrates [PDF]

, 2013
Thesis (PhD)--Stellenbosch University, 2013.ENGLISH ABSTRACT: Mycobacterium tuberculosis, the causative agent of tuberculosis disease, contains five copies of the ESAT-6 gene cluster, each encoding a dedicated ESX protein secretion system which has been
Newton-Foot, Mae
core  

Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts. [PDF]

Microb Genom, 2021
Orgeur M, Frigui W, Pawlik A, Clark S, Williams A, Ates LS, Ma L, Bouchier C, Parkhill J, Brodin P, Brosch R.   +10 more
europepmc   +1 more source

Conserved ESX-1 Substrates EspE and EspF Are Virulence Factors That Regulate Gene Expression. [PDF]

Infect Immun, 2020
Chirakos AE, Nicholson KR, Huffman A, Champion PA.   +3 more
europepmc   +1 more source

Improved immune responses and tuberculosis protection by aerosol vaccination with recombinant BCG expressing ESX-1 from Mycobacterium marinum. [PDF]

PLoS Pathog
Sayes F, Frigui W, Pawlik A, Tillier C, Tichit M, Hardy D, Brosch R.   +6 more
europepmc   +1 more source

The ESX-1 Virulence Factors Downregulate miR-147-3p in Mycobacterium marinum-Infected Macrophages. [PDF]

Infect Immun, 2020
Zuo X, Wang L, Bao Y, Sun J.
europepmc   +1 more source

In vivo regulation of the monocyte phenotype by Mycobacterium marinum and the ESX-1 type VII secretion system. [PDF]

Sci Rep
Munke K, Wulff L, Lienard J, Carlsson F, Agace WW.   +4 more
europepmc   +1 more source

Mucosal delivery of ESX-1-expressing BCG strains provides superior immunity against tuberculosis in murine type 2 diabetes. [PDF]

Proc Natl Acad Sci U S A, 2020
Sathkumara HD, Muruganandah V, Cooper MM, Field MA, Alim MA, Brosch R, Ketheesan N, Govan B, Rush CM, Henning L, Kupz A.   +10 more
europepmc   +1 more source

Uptake-independent killing of macrophages by extracellular aggregates of Mycobacterium tuberculosis is ESX-1 and PDIM-dependent

, 2023
Toniolo C, Dhar N, McKinney JD.
europepmc   +1 more source

Single-cell analysis reveals <i>Mycobacterium tuberculosis</i> ESX-1-mediated accumulation of permissive macrophages in infected mouse lungs. [PDF]

Sci Adv
Zheng W, Borja M, Dorman LC, Liu J, Zhou A, Seng A, Arjyal R, Sunshine S, Nalyvayko A, Pisco AO, Rosenberg OS, Neff N, Zha BS.   +12 more
europepmc   +1 more source

The SapM phosphatase can arrest phagosome maturation in an ESX-1 independent manner in Mycobacterium tuberculosis and BCG. [PDF]

Infect Immun
Xander C, Rajagopalan S, Jacobs WR, Braunstein M.   +3 more
europepmc   +1 more source