Results 51 to 60 of about 1,982 (172)

Gastrointestinal Pathobionts in Pediatric Crohn’s Disease Patients

International Journal of Microbiology, 2018
Crohn’s disease (CD) is an inflammatory disease of the gastrointestinal tract, with a rising incidence worldwide, particularly in children. CD is thought to arise due to an immune response to environmental factors. The role of bacteria in CD has recently
Rachel V. Purcell, Nadeem O. Kaakoush, Hazel M. Mitchell, John F. Pearson, Jacqueline I. Keenan   +4 more
doaj   +1 more source

Progress in the detection of gut microbiota based on microfluidic technology

Interdisciplinary Medicine, Volume 4, Issue 1, January 2026.
Abstract Gut microbiota, a complex microbial community in the human intestine, are vital for digestion, nutrient absorption, and immune regulation, maintaining gut micro‐ecological balance. Accurate detection of its composition, structure, and function is crucial for understanding the relationship between health and disease, early disease diagnosis ...
Yuan Tan, Jiayue Huang, Yi Liu, Xiaofei Lai   +3 more
wiley   +1 more source

KRAS mutations promote the intratumoral colonization of enterotoxigenic bacteroides fragilis in colorectal cancer through the regulation of the miRNA3655/SURF6/IRF7/IFNβ axis

Gut Microbes
KRAS mutations are associated with poor prognosis in colorectal cancer (CRC). Although the association between the gut microbiota and CRC has been extensively documented, it is unclear whether KRAS mutations can regulate the gut microbiota.
Yizhen Chen, Shaolin Liu, Song Tan, Yuanyuan Zheng, Yifan Chen, Changshun Yang, Shengtao Lin, Yulong Mi, Weihua Li   +8 more
doaj   +1 more source

Outer membrane vesicles secreted by pathogenic and nonpathogenic Bacteroides fragilis represent different metabolic activities

Scientific Reports, 2017
Numerous studies are devoted to the intestinal microbiota and intercellular communication maintaining homeostasis. In this regard, vesicles secreted by bacteria represent one of the most popular topics for research.
Natalya B. Zakharzhevskaya, Anna A. Vanyushkina, Ilya A. Altukhov, Aleksey L. Shavarda, Ivan O. Butenko, Daria V. Rakitina, Anastasia S. Nikitina, Aleksandr I. Manolov, Alina N. Egorova, Eugene E. Kulikov, Innokentii E. Vishnyakov, Gleb Y. Fisunov, Vadim M. Govorun   +12 more
doaj   +1 more source

Toxins and Antibiotic Resistance in Staphylococcus aureus Isolated from a Major Hospital in Lebanon [PDF]

, 2016
Molecular characterization of Staphylococcus aureus is of both clinical and infection control importance. Virulence determinants using PCR and multiple drug resistance profiles were studied in 130 S. aureus isolates. PCR-RFLP analysis of the 16S–23S DNA
Andraos, Rana, Araj, George, Haddad, Dominik, Hashwa, Fuad, Tokajian, Sima   +4 more
core   +1 more source

The interplay between tissue‐resident microbiome and host proteins by integrated multi‐omics during progression of colorectal adenoma to carcinoma

iMeta, Volume 4, Issue 6, December 2025.
This study integrated metagenomic and proteomic profiling of 185 colorectal tissue samples—spanning adenoma (A), tumor (T), and para‐tumor (P)—to characterize multi‐kingdom microbiome and host protein dynamics in colorectal cancer (CRC). In total, 4057 bacterial, 61 fungal, 108 archaeal, and 374 viral species were identified, revealing CRC‐specific ...
Di Wu, An‐Jun Wang, De‐Chao Bu, Yan‐Yan Sun, Chen‐Hao Li, Yue‐Mei Hong, Shan Zhang, Shi‐Yang Chen, Jin‐An Zhou, Tian‐Yi Zhang, Min‐Hao Yu, Yong‐Jing Ma, Xiu‐Li Wang, Jia Xu, Wei He, Christopher Heeschen, Jian‐Feng Chen, Wen‐Jun Mao, Hui Ding, Wen‐Juan Wu, Yi Zhao, Hui Wang, Ning‐Ning Liu   +22 more
wiley   +1 more source

MAD‐DDS: Memory‐efficient automatic discovery data distribution service for large‐scale distributed control network

IET Communications, 2023
The rampant deployment of data distribution service (DDS) as middle‐ware service providers for industrial network platforms has been widely investigated.
Williams‐Paul Nwadiugwu, Dong‐Seong Kim, Waleed Ejaz, Alagan Anpalagan   +3 more
doaj   +1 more source

Precision Antimicrobial Therapy Against Fusobacterium nucleatum Using Bioengineered Probiotics Expressing Guided Antimicrobial Peptides (gAMPs)

Microbial Biotechnology, Volume 18, Issue 12, December 2025.
We engineered a probiotic using Lactococcus lactis that targets Fusobacterium nucleatum, a cancer‐associated microbe, by secreting guided antimicrobial peptides (gAMPs) binding to the FomA porin protein. This approach inhibits biofilms, preserves microbial diversity and provides a precise, microbiome‐sparing alternative to broad‐spectrum antibiotics ...
Ankan Choudhury, Colin Scano, Allison Barton, Christopher M. Kearney, K. Leigh Greathouse   +4 more
wiley   +1 more source

The association between fecal enterotoxigenic B. fragilis with colorectal cancer

BMC Cancer, 2019
Background Enterotoxigenic Bacteroides fragilis (ETBF) is an enterotoxin-producing bacterium that possibily has a role in the occurrence and progression of colorectal cancer (CRC) by modulating the mucosal immune response and inducing epithelial cell ...
Fakhri Haghi, Elshan Goli, Bahman Mirzaei, Habib Zeighami   +3 more
doaj   +1 more source

Gut microbiota imbalance and colorectal cancer. [PDF]

, 2016
International audienceThe gut microbiota acts as a real organ. The symbiotic interactions between resident micro-organisms and the digestive tract highly contribute to maintain the gut homeostasis.
Barnich, Nicolas, Bonnet, Mathilde, Bonnet, Richard, Bringer, Marie-Agnès, Buc, Emmanuel, Gagnière, Johan, Pezet, Denis, Raisch, Jennifer, Veziant, Julie   +8 more
core   +5 more sources