Results 21 to 30 of about 510 (164)

Ethosomes: A novel drug carrier

Annals of Medicine & Surgery, 2022
Ethosomal systems are newer lipid vesicular carriers that have been around for 20 years, but over that period they have grown significantly as a means of transdermal drug delivery. They have a sizable amount of ethanol in them. These nanocarriers carry medicinal substances with various physicochemical qualities throughout the skin and deep skin layers.
Chauhan, Neha, Vasava, Parul, Khan, Sharuk L., Siddiqui, Falak A., Islam, Fahadul, Chopra, Hitesh, Emran, Talha Bin   +6 more
openaire   +2 more sources

Quality by Design for Development, Optimization and Characterization of Brucine Ethosomal Gel for Skin Cancer Delivery

Molecules, 2021
Natural products have been extensively used for treating a wide variety of disorders. In recent times, Brucine (BRU) as one of the natural medications extracted from seeds of nux vomica, was investigated for its anticancer activity.
Tamer A. Ismail, Tamer M. Shehata, Dalia I. Mohamed, Heba S. Elsewedy, Wafaa E. Soliman   +4 more
doaj   +1 more source

Design and Characterization of Ethosomes for Transdermal Delivery of Caffeic Acid

Pharmaceutics, 2020
The present investigation describes a formulative study aimed at designing ethosomes for caffeic acid transdermal administration. Since caffeic acid is characterized by antioxidant potential but also high instability, its encapsulation appears to be an ...
Supandeep Singh Hallan, Maddalena Sguizzato, Paolo Mariani, Rita Cortesi, Nicolas Huang, Fanny Simelière, Nicola Marchetti, Markus Drechsler, Tautgirdas Ruzgas, Elisabetta Esposito   +9 more
doaj   +1 more source

Ethosomes and Transethosomes as Cutaneous Delivery Systems for Quercetin: A Preliminary Study on Melanoma Cells

Pharmaceutics, 2022
The present study is aimed to design ethosomes and transethosomes for topical administration of quercetin. To overcome quercetin low bioavailability, scarce solubility and poor permeability that hamper its pharmaceutical use, the drug was loaded in ...
Francesca Ferrara, Mascia Benedusi, Maddalena Sguizzato, Rita Cortesi, Anna Baldisserotto, Raissa Buzzi, Giuseppe Valacchi, Elisabetta Esposito   +7 more
doaj   +1 more source

Ultraflexible Liposome Nanocargo as a Dermal and Transdermal Drug Delivery System

Nanomaterials, 2021
A selected active pharmaceutical ingredient must be incorporated into a cargo carrier in a particular manner so that it achieves its goal. An amalgamation of active pharmaceutical ingredients (APIs) should be conducted in such a manner that it is simple,
Kalvatala Sudhakar, Shivkanya Fuloria, Vetriselvan Subramaniyan, Kathiresan V. Sathasivam, Abul Kalam Azad, Shasank S. Swain, Mahendran Sekar, Sundram Karupiah, Omji Porwal, Alaka Sahoo, Dhanalekshmi Unnikrishnan Meenakshi, Vipin Kumar Sharma, Sanjay Jain, R. Narayana Charyulu, Neeraj Kumar Fuloria   +14 more
doaj   +1 more source

Ethosomal (−)-epigallocatechin-3-gallate as a novel approach to enhance antioxidant, anti-collagenase and anti-elastase effects

Beilstein Journal of Nanotechnology, 2022
Controlled release systems containing natural compounds have been successfully applied in cosmetics as antiaging products to enhance the penetration of active compounds through the skin.
Çiğdem Yücel, Gökçe Şeker Karatoprak, Sena Yalçıntaş, Tuğba Eren Böncü   +3 more
doaj   +1 more source

Trans ethosomal hybrid composites of naproxen-sulfapyridine in hydrogel carrier: anti-inflammatory response in complete Freund’s adjuvant induced arthritis rats

Artificial Cells, Nanomedicine, and Biotechnology, 2022
Current treatment for Rheumatoid arthritis (RA) utilizes Disease-modifying antirheumatic drugs, non-steroidal anti-inflammatory drugs or its combination, to decrease joint inflammation.
Sajeev Kumar Babasahib, Roaddy Well Born, Nulgumnalli Manjunathaiah Raghavendra   +2 more
doaj   +1 more source

“Plurethosome” as Vesicular System for Cutaneous Administration of Mangiferin: Formulative Study and 3D Skin Tissue Evaluation

Pharmaceutics, 2021
Human skin is dramatically exposed to toxic pollutants such as ozone. To counteract the skin disorders induced by the air pollution, natural antioxidants such as mangiferin could be employed.
Maddalena Sguizzato, Francesca Ferrara, Paolo Mariani, Alessia Pepe, Rita Cortesi, Nicolas Huang, Fanny Simelière, Paola Boldrini, Anna Baldisserotto, Giuseppe Valacchi, Elisabetta Esposito   +10 more
doaj   +1 more source

Formulation, characterization, and in vitro testing of azelaic acid ethosome-based cream against Propionibacterium acnes for the treatment of acne

Journal of Advanced Pharmaceutical Technology & Research, 2019
Azelaic acid is an antiacne drug by inhibiting thioredoxin reductase enzyme of Propionibacterium acnes (P. acnes) that affects the inhibition of bacterial DNA synthesis which occurs in the cytoplasm.
Elsa Fitria Apriani, Yeva Rosana, Iskandarsyah Iskandarsyah   +2 more
doaj   +1 more source

Improving the Antitumor Activity and Bioavailability of Sonidegib for the Treatment of Skin Cancer

Pharmaceutics, 2021
Throughout the United States and the world, skin cancer is the most frequent form of cancer. Sonidegib (SNG) is a hedgehog inhibitor that has been used for skin cancer treatment. However, SNG has low bioavailability and is associated with resistance. The
Amr Gamal, Haitham Saeed, Fatma I. Abo El-Ela, Heba F. Salem   +3 more
doaj   +1 more source