Results 41 to 50 of about 510 (164)

Development and Optimization of a Nanophytosomes‐Based Thermogel as a Topical Anti‐Psoriatic for Increased Solubility and Bioavailability

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
Schematic illustration of the development, optimization, and therapeutic evaluation of the Leucas aspera phytosome‐based thermogel for topical antipsoriatic therapy, highlighting its enhanced solubility, skin deposition, and in vivo efficacy in an imiquimod‐induced psoriasis model. Created with BioRender.com.
Ananda Kumar Chettupalli   +2 more
wiley   +1 more source

Preparation of curcumin ethosomes

open access: yesAfrican Journal of Pharmacy and Pharmacology, 2013
This study aims to prepare a novel curcumin ethosomes and investigate its properties as a drug delivery system of curcumin. A new modified method combining thin-film hydration and ultrasound was used to prepare ethosomes. Particle size was determined using Mastersizer 3000 laser diffraction analyzer.
openaire   +2 more sources

Microglial Activation Under Hypoxic Conditions in Early Alzheimer's Disease: Can Natural SIRT1 Activators Be Therapeutic Allies in the Inflammation–Energy Axis?

open access: yesPhytotherapy Research, Volume 40, Issue 6, Page 3354-3368, June 2026.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative condition characterized by a preclinical stage that typically lasts for decades. Early on during this time, microglia react to pathological changes and become protective and even transiently delay neurodegeneration.
Sara Merlo   +3 more
wiley   +1 more source

Formulation, Development and Characterization of Ethosomes of Atorvastatin

open access: yesInternational Journal of Pharmaceutical Investigation, 2019
Objectives: The main objective of the present investigation was to develop transdermal delivery of Atorvastatin, a HMG-CoAreductase inhibitor used in the treatment of congestive heart failure (CHF). Atorvastatin was formulated into ethosomal formulation to reduce the first pass metabolism and increase the systemic bioavailability.
S Agarwal, G Gautam
openaire   +2 more sources

EtoGel for Intra-Articular Drug Delivery: A New Challenge for Joint Diseases Treatment

open access: yesJournal of Functional Biomaterials, 2021
Ethosomes® have been proposed as potential intra-articular drug delivery devices, in order to obtain a longer residence time of the delivered drug in the knee joint.
Maria Chiara Cristiano   +5 more
doaj   +1 more source

Skin Boosters: 2026 Updated

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Skin boosters are increasingly used to improve dermal quality through injectable and device‐assisted approaches; however, definitions and clinical evidence remain heterogeneous. Aims To provide an updated overview and propose a practical classification of skin boosters, including mechanisms, delivery methods, clinical outcomes, and limitations.
Kyu‐ho Yi   +7 more
wiley   +1 more source

Nanovesicles and Human Skin Interaction: A Comparative Ex-Vivo Study

open access: yesNanomaterials
The topical administration of drugs on the skin by nanovesicular systems can represent a tool to treat skin pathologies. The study of nanovesicle biodistribution after skin administration is crucial to understanding their transdermal potential.
Elisabetta Esposito   +14 more
doaj   +1 more source

Curcumin Nanoformulations for Dermatological Applications: From Nutraceuticals to Nanocarriers

open access: yesFood Frontiers, Volume 7, Issue 3, May 2026.
Nanotechnology‐based delivery platforms enhance the cutaneous administration of curcumin. Loading free curcumin into polymeric micelles, metal‐based nanoparticles, nanogels/hydrogels, liposomes, polymeric nanoparticles, or nanoemulsions/nanocrystals helps address its low solubility, poor stability and limited skin permeation. As a result, these systems
Stephany Celeste Gutiérrez‐Ruiz   +13 more
wiley   +1 more source

Mechanism investigation of ethosomes transdermal permeation

open access: yesInternational Journal of Pharmaceutics: X, 2019
Ethosomes are widely used to promote transdermal permeation of both lipophilic and hydrophilic drugs, but the mechanism of interaction between the ethosomes and the skin remains unclear. In this work, it was exploded with several technologies and facilities.
Xiao-Qian Niu   +10 more
openaire   +3 more sources

Nanotechnology in Dermatology: A Comprehensive Narrative Review of Performance, Safety, and Clinical Translation

open access: yesHealth Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Nanotechnology has emerged as a transformative approach in dermatology, offering potential for enhanced drug delivery, targeted therapy, and improved bioavailability for various skin conditions. However, despite significant research output, translational barriers persist due to heterogeneous study designs, safety concerns, and ...
Mohammed Saleh Al‐Dhubaibi   +5 more
wiley   +1 more source

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