Results 111 to 120 of about 34,162 (142)
Some of the next articles are maybe not open access.
Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova, 2023
Objective. To evaluate an effect of ethylmethylhydroxypyridine succinate and ethylmethylhydroxypyridine malate on changes in mitochondrial function under experimental focal cerebral ischemia. Material and methods. Focal cerebral ischemia was modeled in Wistar rats by thermocoagulation of the middle cerebral artery. Ethylmethylhydroxypyridine succinate (
Denis Zolotykh +2 more
exaly +3 more sources
Objective. To evaluate an effect of ethylmethylhydroxypyridine succinate and ethylmethylhydroxypyridine malate on changes in mitochondrial function under experimental focal cerebral ischemia. Material and methods. Focal cerebral ischemia was modeled in Wistar rats by thermocoagulation of the middle cerebral artery. Ethylmethylhydroxypyridine succinate (
Denis Zolotykh +2 more
exaly +3 more sources
Effectiveness of Ethylmethylhydroxypyridine Succinate in Alcohol Withdrawal
Psychopharmacology & biological narcologyBACKGROUND: Alcohol (ethanol) use disorder is a destructive condition with alterations in impaired energy and metabolic processes and activation of free radical oxidation processes. Therefore, the use of antioxidants in the complex therapy of this pathology is pathogenetically justified, one of which is the original domestic drug ...
Elena Yakusheva, Aleksey Shchulkin
exaly +2 more sources
S.S. Korsakov Journal of Neurology and Psychiatry, 2023
Objective. To investigate the therapeutic efficacy and tolerability of Mexicor as an adjuvant in the treatment of depression with SSRI antidepressants. Material and methods. The study included 100 patients, aged 18—50 years, with verified depression of mild (n=32) or moderate (n=68) severity.
V.E. Medvedev, V.I. Frolova, A.V. Palin
openaire +2 more sources
Objective. To investigate the therapeutic efficacy and tolerability of Mexicor as an adjuvant in the treatment of depression with SSRI antidepressants. Material and methods. The study included 100 patients, aged 18—50 years, with verified depression of mild (n=32) or moderate (n=68) severity.
V.E. Medvedev, V.I. Frolova, A.V. Palin
openaire +2 more sources
Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova, 2020
Chronic cerebral ischemia (CCI) is a common cerebrovascular syndrome, the development of which is associated with a high risk of increasing cognitive, behavioral, and motor disorders, and the formation of a patient's dependence on others. Timely start of treatment can slow down the course of the disease, make it more favorable. The review considers the
Alexei Prokofiev +2 more
exaly +3 more sources
Chronic cerebral ischemia (CCI) is a common cerebrovascular syndrome, the development of which is associated with a high risk of increasing cognitive, behavioral, and motor disorders, and the formation of a patient's dependence on others. Timely start of treatment can slow down the course of the disease, make it more favorable. The review considers the
Alexei Prokofiev +2 more
exaly +3 more sources
Efficacy and safety of ethylmethylhydroxypyridine succinate in patients with ischemic stroke
Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2020Stroke is still the most significant problem of the modern medicine and the leading cause of mortality and morbidity. There is the great experience of neuroprotection in patients with stroke in the Russian Federation. In clinical practice it's important to follow conditions, where neuroprotection will have maximum safety and effectiveness. The clinical
M V, Zhuravleva +7 more
openaire +2 more sources
Geroprotective effects of ethylmethylhydroxypyridine succinate in an experimental study
Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2020To study an effect of mexidol on the life expectancy, weight, seizure response thresholds, and impaired cognitive and motor functions during aging in male Wistar rats.In a long-term experiment, male Wistar rats, aged 3-26 months, were assessed for impaired cognitive functions (passive avoidance conditioned reflex test), convulsive threshold (test with ...
openaire +2 more sources
Mechanism of Myogenesis Stimulation by Ethylmethylhydroxypyridine Succinate
Pharmaceutical Chemistry JournalElena Yakusheva, Aleksey Shchulkin
exaly +2 more sources
The Study of the Effectiveness of Ethylmethylhydroxypyridine Succinate in Acute Alcohol Intoxication
Bulletin of Experimental Biology and MedicineThe effectiveness of ethylmethylhydroxypyridine succinate (EMHPS) in acute alcohol intoxication was tested in a study on SPF male outbred ICR mice. Ethanol (concentration 40%) was administered to animals once intraperitoneally at a dose of 4 g/kg. Control animals were injected with saline in an equivalent volume.
Aleksey Shchulkin
exaly +3 more sources
Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2016
To study the therapeutic action of ethylmethylhydroxypyridine succinate (mexidol) on the neurodegeneration in multiple sclerosis (MS).Fifty-two MS patients and 24 healthy controls were examined using DTI MRI with tractography.Ethylmethylhydroxypyridine succinate can prevent the progression of neurodegenerative processes in MS. However, further clinical
L N, Prakhova +6 more
openaire +2 more sources
To study the therapeutic action of ethylmethylhydroxypyridine succinate (mexidol) on the neurodegeneration in multiple sclerosis (MS).Fifty-two MS patients and 24 healthy controls were examined using DTI MRI with tractography.Ethylmethylhydroxypyridine succinate can prevent the progression of neurodegenerative processes in MS. However, further clinical
L N, Prakhova +6 more
openaire +2 more sources